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All Journal Indonesian Journal of Cancer Chemoprevention Jurnal Bioteknologi & Biosains Indonesia (JBBI) Pharmasipha JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Mandala Pharmacon Indonesia Jurnal Ners Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Farmasi dan Sains Indonesia (JFSI) Indonesian Journal of Pharmaceutical Education International Journal of Science and Society (IJSOC) Jurnal Multidisiplin Madani (MUDIMA) East Asian Journal of Multidisciplinary Research (EAJMR) Formosa Journal of Multidisciplinary Research (FJMR) Jurnal Farmasi Sains dan Praktis Jurnal Kesehatan Tropis Indonesia Calakan: Jurnal Sastra, Bahasa, dan Budaya Fundamental : Jurnal Ilmiah Hukum
Ismi Rahmawati
Faculty of Pharmacy, Setia Budi University  
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Antioxidant Activity Test of 2,6-bis-(2’-furilidyn)-Cyclohexanone, ; 2,5-bis-(2’-furilidyn)-Cyclopentanone; 1,5-Difuryl-1,4-pentadien-3-one Rahmawati, Ismi; Rejeki, Endang Sri; Sardjiman, .
Indonesian Journal of Cancer Chemoprevention Vol 1, No 1 (2010)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4.399 KB)

Abstract

Antioxidant is an essential compound to keep man’s health due to its function as radical scavenging. Curcumin analog  compounds can function as antioxidant (Sardjiman, 2000). The aim of the experiment was to find out the antioxidant activity of 2,.6-bis-(2’-furilidin)-cyclohexanone, 2,.5-bis-(2’furilidin)-cyclopentanone, and 1,.5-difuril-1.4-pentadien-3-one compounds, and the antioxidant activity of each compound against DPPH  radical with IC50 parameter as well as the correlation of compounds structure’s activities against antioxidant.  The antioxidant activity of curcumin analog compounds wereas tested against DPPH free  radical. The test was conducted in 5 series of concentrations by adding 4.0  ml test solutions with 1.0 ml DPPH. The antioxidant activity against free radical was measured usingwith spectrophotometer at 517 nm wavelength and determined for the IC50 value. The experiment employed rutin as positive control. The result of the experiment showed that curcumin analog compounds have antioxidant  activity with IC50 of rutin, 2,.6-bis-(2’-furilidin)-cyclohexanone, 2,.5-bis-(2’furilidin)-cyclopentanone, and 1,.5-difuril-1.4-pentadien-3-one as follows: 4.93 ppm, 22.73 ppm, 20.67 ppm, and 18.80 ppm  respectively. The highest antioxidant activity belonged to  1,.5-difuril-1.4-pentadien-3-one compound which is 18.80 ppm . Correlation of activity structure of the 3 compounds can be seen from the log p parameter and energy space of HOMO-LUMO. 
UJI AKTIVITAS ANTIJAMUR BEBERAPA SENYAWA MONOKARBONIL ANALOG CURCUMIN HASIL SINTESIS Rahmawati, Ismi; Purwaningsih, Desi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol 5, No 2 (2018): December 2018
Publisher : Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1138.101 KB) | DOI: 10.29122/jbbi.v5i2.2835

Abstract

Antifungal Activity of Some Synthesized Mono-Carbonyl Analogue Compounds of CurcuminABSTRACTFungal resistance can pose a threat to future fungal infections, therefore studies to find other compounds that have antifungal activity need to be done. The aim of this study was to examine antifungal activity of synthesized curcumin analogue compounds i.e. 2,6-Bis-(2'-furilidin)-cyclohexanone (26FuH); 2,5-Bis-(2'-furilidine)-cyclopentanone (25FuP) and 1,5-Difuril-1,4-pentadien-3-on (15FuA). The curcumin analogue compound was successfully synthesized with Aldol condensation using KOH 7.5% as the catalyst. The compound was purified and characterized by melting point, thin layer chromatography, gas chromatography with mass spectrometry, FTIR spectrophotometry, spectrophotometry 1H-NMR. The results showed pure compounds and have a structure that corresponds to the target compounds. All compound were assayed as antifungal against Candida albicans, Pityrosporum ovale, Aspergillus niger, and Trichophyton mentagrophytes. The activity of each compound represented by inhibitory diameter was analyzed by one-way ANOVA followed by post hoc Tukey (p<0.05). All three compounds showed antifungal activity against Candida albicans, Pityrosporum ovale, and Aspergillus niger. The best antifungal activity was shown by 26FuH against Pityrosporum ovale.Keywords: antifungal activity, curcumin, monocarbonyl, Pityrosporum ovale, synthesis ABSTRAKResistensi jamur dapat menjadi ancaman pada kasus infeksi jamur di masa mendatang, oleh sebab itu penelitian untuk menemukan senyawa lain yang memiliki aktivitas antijamur perlu dilakukan. Penelitian ini bertujuan untuk menguji aktivitas antijamur senyawa analog curcumin hasil sintesis yaitu senyawa 2,6-Bis-(2’-furilidin)-sikloheksanon (26FuH); 2,5-Bis-(2’-furilidin)-siklopentanon (25FuP) dan 1,5-Difuril-1,4-pentadien-3-on (15FuA). Senyawa analog curcumin sudah berhasil disintesis dengan metode kondensasi Aldol menggunakan katalis KOH 7,5%. Senyawa hasil sintesis dimurnikan dan dikarakterisasi dengan menggunakan pemeriksaan organoleptis, titik lebur, kromatografi lapis tipis, kromatografi gas dengan spektrometri massa, spektrofotometri FTIR, spektrofotometri 1H-NMR. Hasil menunjukkan senyawa murni dan struktur sesuai senyawa target. Hasil sintesis diuji aktivitas antijamur terhadap Candida albicans, Pityrosporum ovale, Aspergillus niger dan Trichophyton mentagrophytes. Hasil diameter daya hambat dianalisis dengan ANOVA satu arah dilanjutkan post hoc Tukey (p<0,05). Ketiga senyawa memiliki aktivitas antijamur terhadap jamur Candida albicans, Pityrosporum ovale, dan Aspergillus niger. Aktivitas antijamur terbaik adalah senyawa 26FuH terhadap jamur Pityrosporum ovale.Kata Kunci: aktivitas antijamur, curcumin, monokarbonil, Pityrosporum ovale, sintesis
UJI AKTIVITAS ANTIJAMUR BEBERAPA SENYAWA MONOKARBONIL ANALOG CURCUMIN HASIL SINTESIS Rahmawati, Ismi; Purwaningsih, Desi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 5 No. 2 (2018): December 2018
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1138.101 KB) | DOI: 10.29122/jbbi.v5i2.2835

Abstract

Antifungal Activity of Some Synthesized Mono-Carbonyl Analogue Compounds of CurcuminABSTRACTFungal resistance can pose a threat to future fungal infections, therefore studies to find other compounds that have antifungal activity need to be done. The aim of this study was to examine antifungal activity of synthesized curcumin analogue compounds i.e. 2,6-Bis-(2'-furilidin)-cyclohexanone (26FuH); 2,5-Bis-(2'-furilidine)-cyclopentanone (25FuP) and 1,5-Difuril-1,4-pentadien-3-on (15FuA). The curcumin analogue compound was successfully synthesized with Aldol condensation using KOH 7.5% as the catalyst. The compound was purified and characterized by melting point, thin layer chromatography, gas chromatography with mass spectrometry, FTIR spectrophotometry, spectrophotometry 1H-NMR. The results showed pure compounds and have a structure that corresponds to the target compounds. All compound were assayed as antifungal against Candida albicans, Pityrosporum ovale, Aspergillus niger, and Trichophyton mentagrophytes. The activity of each compound represented by inhibitory diameter was analyzed by one-way ANOVA followed by post hoc Tukey (p&lt;0.05). All three compounds showed antifungal activity against Candida albicans, Pityrosporum ovale, and Aspergillus niger. The best antifungal activity was shown by 26FuH against Pityrosporum ovale.Keywords: antifungal activity, curcumin, monocarbonyl, Pityrosporum ovale, synthesis ABSTRAKResistensi jamur dapat menjadi ancaman pada kasus infeksi jamur di masa mendatang, oleh sebab itu penelitian untuk menemukan senyawa lain yang memiliki aktivitas antijamur perlu dilakukan. Penelitian ini bertujuan untuk menguji aktivitas antijamur senyawa analog curcumin hasil sintesis yaitu senyawa 2,6-Bis-(2’-furilidin)-sikloheksanon (26FuH); 2,5-Bis-(2’-furilidin)-siklopentanon (25FuP) dan 1,5-Difuril-1,4-pentadien-3-on (15FuA). Senyawa analog curcumin sudah berhasil disintesis dengan metode kondensasi Aldol menggunakan katalis KOH 7,5%. Senyawa hasil sintesis dimurnikan dan dikarakterisasi dengan menggunakan pemeriksaan organoleptis, titik lebur, kromatografi lapis tipis, kromatografi gas dengan spektrometri massa, spektrofotometri FTIR, spektrofotometri 1H-NMR. Hasil menunjukkan senyawa murni dan struktur sesuai senyawa target. Hasil sintesis diuji aktivitas antijamur terhadap Candida albicans, Pityrosporum ovale, Aspergillus niger dan Trichophyton mentagrophytes. Hasil diameter daya hambat dianalisis dengan ANOVA satu arah dilanjutkan post hoc Tukey (p&lt;0,05). Ketiga senyawa memiliki aktivitas antijamur terhadap jamur Candida albicans, Pityrosporum ovale, dan Aspergillus niger. Aktivitas antijamur terbaik adalah senyawa 26FuH terhadap jamur Pityrosporum ovale.Kata Kunci: aktivitas antijamur, curcumin, monokarbonil, Pityrosporum ovale, sintesis
Aktivitas Antibiofilm Ekstrak dan Fraksi-Fraksi Biji Pinang (Areca catechu L.) Terhadap Staphylococcus aureus ATCC 25923 Tobi, Claudius Hendraman B.; Saptarini, Opstaria; Rahmawati, Ismi
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 7, No 1 (2022)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v7i1.43698

Abstract

Biofilm merupakan kumpulan dari sel-sel mikrobial yang melekat secara ireversibel pada suatu permukaan dan terbungkus dalam matriks EPS (Extracellular PolymericSubstances). Salah satu bakteri infeksius yang memproduksi biofilm adalah S. aureus. Biji pinang diketahui mengandung flavonoid, alkaloid dan tanin yang memiliki mekanisme antibiofilm dan antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antibiofilm ekstrak dan fraksi biji pinang terhadap bakteri S. aureus. Ekstraksi biji pinang dilakukan dengan metode maserasi, fraksinasi dilakukan dengan metode ekstraksi cair-cair menggunakan pelarut air, etil asetat dan n-heksan. Aktivitas penghambatan dan degradasi biofilm dilakukan dengan metode pewarnaan kristal violet yang dibaca pada panjang gelombang 595 nm. Persen peghambatan dan degradasi yang diperoleh dianalisis menggunakan uji statistik ANAVA dua arah. Persen penghambatan dan degradasi tertinggi ditunjukkan oleh ekstrak etanolyaitu secara berturut-turut 70,17% dan 54%dengan nilai IC50 secara berturut-turut yaitu -0,4 mg/ml dan 5,9 mg/ml. Hasil uji statistik menunjukkan setiap kelompok sampel dan konsentrasi memberikan pengaruh yang signifikan pada persen penghambatan dan degradasi biofilm.
Efek kombinasi ekstrak etanol daun kelor (Moringa oleifera L.) dan daun kemangi (Ocimum basilicum L.) terhadap bakteri Staphylococcus aureus Sari, Dewi Arum; Rahmawati, Ismi; Puspitasari, Ismi
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 7 No. 2 (2023): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v7i2.10037

Abstract

ABSTRACT Resistance of bacteria oftenly occur to Staphylococcus aureus bacteria. Bacterial resistance to antibiotics causes the increase of death rate. Moringa and basil leaves contain active compounds i.e flavonoids, alkaloids, saponins, and tannins that have the potential as antibacterial against Staphylococcus aureus. This study aims to determine the activity of the combination of ethanol extract of moringa and basil leaves against Staphylococcus aureus. They were extracted by maceration method using 96% ethanol solvent and then identified the group of compounds. Preliminary tests were carried out using the liquid dilution method to obtain the MIC value of each extract. The combination of moringa leaf extract and basil leaf extract was carried out in concentration with a ratio of 1:1; 1:2; and 2:1. The antibacterial activity test was carried out using disc diffusion method, to determine the best results, statistical tests were carried out with Shapiro Wilk and Levene homogenity continued by one way ANOVA, post-hoc tukey. Determination of combination effect between two extract were done by paper tape method. The results showed that the combination of ethanol extracts of moringa and basil leaves had antibacterial activity against Staphylococcus aureus. The combination concentration of 1:2 was the most effective combination with an average inhibition zone diameter of 15.46 ± 0.003 mm and provided a synergistic combination effect against Staphlococcus aureus. Keywords:  antibacterial, moringan leaf, basil leaf, Staphylococcus aureus   ABSTRAK Resistensi bakteri sering terjadi pada bakteri Staphylococcus aureus. Kekebalan bakteri terhadap antibiotik menyebabkan angka kematian semakin meningkat. Daun kelor dan daun kemangi mengandung senyawa aktif flavonoid, alkaloid, saponin, dan tanin yang berpotensi sebagai antibakteri terhadap Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri kombinasi ekstrak etanol daun kelor dan daun kemangi terhadap Staphylococcus aureus. Daun kelor dan daun kemangi di ekstraksi dengan metode maserasi menggunakan pelarut etanol 96% lalu dilakukan identifikasi golongan senyawa. Dilakukan uji pendahuluan dengan metode dilusi cair untuk memperoleh nilai KHM masing- masing ekstrak. Kombinasi ekstrak daun kelor dan daun kemangi dilakukan variasi konsentrasi dengan perbandingan 1:1; 1:2; dan 2:1. Pengujian aktivitas antibakteri dilakukan dengan metode difusi cakram, untuk menentukan hasil terbaik dilakukan uji statistik dengan Shapiro wilk dan homogenitas Levene dilanjutkan one way ANOVA, post-hoc Tukey. Penentuan efek kombinasi kedua ekstrak dengan dilakukan dengan metode pita kertas. Hasil penelitian menunjukkan bahwa kombinasi ekstrak etanol daun kelor dan kemangi mempunyai aktivitas antibakteri terhadap Staphylococcus aureus. Konsentrasi kombinasi 1:2 merupakan kombinasi yang paling efektif dengan rata-rata diameter zona hambat 15,46 ± 0,003 mm dan memberikan efek kombinasi sinergis terhadap Staphlococcus aureus.  Kata Kunci: antibakteri, daun kelor, daun kemangi, Staphylococcus aureus
Analisis Kepribadian Tokoh Utama Dalam Cerita Pendek Lamb to the Slauher Karya Roald Dahl Rahmawati, Ismi
Calakan : Jurnal Sastra, Bahasa, dan Budaya Vol. 3 No. 1 (2025): Maret
Publisher : PT. Alahyan Publisher Sukabumi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61492/calakan.v3i1.192

Abstract

This study aims to explain the main character in the short story Lamb to the Slaughter by Roald Dahl. The attitude and characteristics of the main character Mrs. Mary Maloney and how the main character's personality is described in the story. The research uses several theories, such as character and characterization theory. personality theory. Character is a habit of the process of action that is carried out by individuals repeatedly, and characterization refers to the description of the author and the development of the character (Griffith, 1982: 29). There are three categories of characters according to William Kenney (1966:27), based on their function: characters are divided into several types, namely: main characters, secondary characters, and supporting characters. Characterization is the way a writer displays the personality of a character. Both direct and indirect characterizations are used to express characteristics. There are two types of characterization methods: direct and indirect which refer to research results. Keywords: Characteristics; Main Figures; Short Story.  
Pendekatan Lean Hospital untuk Mengidentifikasi Waste Kritis di Pelayanan Instalasi Farmasi Rawat Jalan RSUD Soehadi Prijonegoro Sragen Prayitno, Krisdita Sundari Putri; Peranginangin, Jason Merari; Rahmawati, Ismi
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.40982

Abstract

Pendekatan lean adalah metode pendekatan sistemik yang digunakan untuk menghilangkan waste yang terjadi dalam pelayanan dan meningkatkan efesiensi pelayanan di suatu instalasi. Proses pelayanan kesehatan disuatu rumah sakit terdapat banyak sekali pemborosan terjadi, contohnya mengulangi kegiatan untuk perbaikan diakibatkan adanya kesalahan, meminta pasien untuk menginformasikan data pasien secara berulangkali untuk memastikan ketetapan informasi, dan sebagainya. Tujuan penelitian ini untuk mengidentifikasi waste dan akar penyebab waste yang terjadi di dalam Instalasi Farmasi Rawat Jalan RSUD Soehadi Prijonegoro Sragen. Metode penelitian ini adalah penelitian studi kasus dengan pendekatan kualitatif. Penelitian ini dilakukan di RSUD Soehadi Prijonegoro Sragen pada bulan Juni-juli 2022 dengan tahapan penelitian yaitu observasi dibuat dalam bentuk VSM, penyebaran kuisioner value pasien dan waste, melakukan wawancara dengan metode 5 why untuk mengetahui akar penyebab dan waste kritis, serta usulan perbaikan. Hasil penelitian menunjukan waste defect 21,1%. Transportation 18,1%, overproduction 16,3%,. Akar penyebab dari waste defect adalah kurang fokusnya petugas dan kurangnya sumber daya manusia, waste transportation adalah kekosongan obat dan tata letak yang kurang rapi, waste waiting adalah pasien harus mengantri di kasir dan pengambilan obat. Usulan perbaikan waste defect adalah penambahan SDM, waste transportation adalah mengatur tata letak rak obat yang lebih rapi, waste overproduction adalah tidak membuat racikan sebelum resep masuk.
Clay Mask Formulation with Moringa oleifera Leaf Extract and Antibacterial Activity Against Staphylococcus aureus Dewi, Nila Audri Risdiana; Rahmawati, Ismi; Purnamasari, Nur Aini Dewi
Indonesian Journal of Pharmaceutical Education Vol 5, No 1 (2025): January–April 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i1.26870

Abstract

Moringa leaves contain tannins, flavonoids, phenols, alkaloids and steroids as antibacterials. One of the causes of acne is Staphylococcus aureus infection. Cosmetic clay mask that can be used for acne skin care. Variations in kaolin concentration can affect the drying time of clay mask preparations. This research aims to determine the clay mask formula for Moringa leaf extract with a variety of kaolin which has physical quality, good stability and antibacterial activity against S. aureus. This research uses 10% Moringa leaf active ingredient which is extracted using the maceration method with 70% ethanol. The clay mask formula consists of kaolin, bentonite, glycerin, DMDM hydantoin, xanthan gum, rose oil and distilled water. The clay mask formula made has varying kaolin concentrations of 30% (F1), 35% (F2) and 40% (F3). The results of formulations F1, F2, and F3 were tested for physical quality and stability and tested for antibacterial activity against S. aureus ATCC 25923. The statistical test for the activity of clay masks F1, F2, and F3 was not significantly different (Sig0.05), but F2 had the highest inhibitory power.  The statistical results of the stability of F1, F2, and F3 are not significantly different (Sig0.05). The results of research on Moringa leaf extract clay masks with variations in kaolin concentration. F1 did not meet the adhesion and viscosity test requirements, while F2 and F3 have physical quality and stability tests that meet the requirements. Moringa leaf extract clay mask has strong antibacterial activity against S. aureus in all three formulas. F1, F2 and F3 with a diameter resistance of 17.44 respectively; 18.56 and 17.67 mm. F2 is the best Moringa leaf extract clay mask formula based on physical quality, stability and antibacterial activity against S. aureus.
The Evaluasi Perencanaan dan Pengadaan Obat e-Catalogue Strategi Perbaikan dengan Metode Hanlon Tahun 2018 di RSUD X Sulawesi Tenggara Irwandi, Irwandi; Rahmawati, Ismi; Wijayanti, Tri
JURNAL KESEHATAN TROPIS INDONESIA Vol. 1 No. 3 (2023): Juni
Publisher : PT. LARPA JAYA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63265/jkti.v1i3.25

Abstract

Instalasi Farmasi Rumah Sakit RSUD X memiliki permasalahan perbedaan antara perencanaan dan pengadaan obat. Hal ini menyebabkan pengelolaan perbekalan farmasi yang tidak efektif. Penelitian ini bertujuan mengetahui proses perencanaan dan pengadaan obat serta mengetahui rencana strategi perbaikan perencanaan dan pengadaan obat e-catalogue di RSUD X. Penelitian dilakukan dengan rancangan penelitian menggunakan data retrospektif dan data concurrent. Data retrospektif diperoleh dengan penelusuran terhadap dokumen tahun 2018 berupa data laporan keuangan, laporan perencanaan, pengadaan dan pemakaian sedian farmasi, alat kesehatan dan bahan medis habis pakai. Hasil penelitian menunjukkan bahwa proses perencanaan dan pengadaan obat e-catalogue belum baik, dikarenakan masih banyaknya hasil yang didapat belum sesuai dengan standar yang telah ditentukan. Rencana strategi yang dapat dilakukan perlu adanya pengusulan kenaikan anggaran pengadaan obat, mencari akar masalah ketidaksesuaian item sediaan farmasi antara perencanaan dan pengadaan, memperpendek proses administrasi pencairan dana, memperbaiki regulasi dalam sistem internal perencanaan dan pengadaan, perbaikan stok sediaan farmasi, pelatihan mengenai Inventory Control Management serta meninjau kembali rekanan pengadaan yang memenuhi aspek mutu produk terjamin, legal dan harga murah.
IMPROVEMENT STRATEGY OF DRUG MANAGEMENT AT PHARMACY INSTALLATION OF HARAPAN INSAN SENDAWAR HOSPITAL BY REVIEWING SUPPORTING MANAGEMENT THROUGH SWOT APPROACH Al-Mubarak, AgustiQori; Rahmawati, Ismi; Oetari, Oetari
Jurnal Farmasi Sains dan Praktis Vol 11 No 1 (January-April 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i1.11258

Abstract

Optimal drug management and drug inventory control can minimize costs and the number of orders in the next planning period. The purpose of this study was to evaluate drug management in the Pharmacy Installation of Harapan Insan Sendawar Hospital with SWOT analysis improvement strategies. The research design was descriptive based on retrospective and concurrent data. All quantitative data were compared with the indicators of The Department of Health (2008), WHO (1993), Minister of Health Regulation (2013), and Pudjaningsih in Satibi (2022). Furthermore, qualitative analysis was carried out with a SWOT approach as an alternative improvement strategy in the Pharmacy Installation based on quantitative data output and internal capital and external influences. The results of the study that meet the standards are: the level of drug availability (15,6 months) and the average prescription service time (non-compounded prescription 23,37 minutes & prescription 39,8 minutes). Results that did not meet the standard were: percentage of stock card matches with drugs (94,73%), inventory turnover ratio (2,22 times), percentage of expired drugs (4,7%), percentage of dead stock (8,97%), number of drug items per prescription sheet (3,57 items), percentage of generic drug prescriptions (76,25%). SWOT analysis of the pharmacy installation falls within the first quadrant, namely focusing on development, improving services and establishing cooperation. The conclusion drawn is that pharmacy installations can adopt aggressive strategies by enhancing the development of management information systems to optimize inventory control.
Co-Authors . Sardjiman Akune, Nadia Ayuwanda S Al-Mubarak, AgustiQori Ana Indrayati Arvian, Dias Wahyu Aryani, Norsarida Bambang Hartono Claudius Hendraman B. Tobi Desi Purwaningsih Dewi Arum Sari Dewi, Lucia VIta Inandha Dewi, Nila Audri Risdiana Endang Diyah Ikasari Endang Sri Rejeki Ika Purwidyaningrum Ilham Kuncahyo, Ilham Irwandi Irwandi Jason Merari Peranginangin Niva, Oktiva Cheria Kairul Oetari, Oetari Opstaria saptarini Prayitno, Krisdita Sundari Putri Purnamasari, Nur Aini Dewi Puspitasari, Ismi Setyaningrum, Dewi Anggraheni Sulaiman, Saifullah Sutrisno, Sahya Rania Tongkonoo, Mutiah Tri Wijayanti Youpita, Nyoman Yovi Pranata Zainudin Hasan