Sasotya, RM Sonny
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Comparison of Clinical Characteristics between Pregnant Women Confirmed with Covid-19 with and Without Severe Preeclampsia Pangaribuan, Roma Berlian; Anwar, Anita Deborah; Sasotya, RM Sonny
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 3 November 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i3.701

Abstract

Background:Several clinical studies have reported that COVID-19 was associated with an increased risk of preeclampsia and preeclampsia-like syndrome in infected pregnant women, but the results are still controversial. This study aims to compare the clinical characteristics of pregnant women with confirmed COVID-19 with and without severe preeclampsia.Methods:This retrospective study of pregnant women confirmed for COVID-19 was carried out at RSUP Dr. Hasan Sadikin from April 1st, 2020 to April 30th, 2022. Epidemiological data, clinical features, and laboratory results of subjects with and without severe preeclampsia in pregnant COVID-19 patients were collected and analyzedResults: Eighty-six subjects were in our study, with 42 subjects with severe preeclampsia and 44 subjects without severe preeclampsia. The average age of mothers in this study was 26 years, with a more significant proportion at term. The proportion of primigravida with severe preeclampsia was significantly more than those without severe preeclampsia (71.42% vs 29.54%, p=0.02). There was no significant difference in clinical severity between patients with or without severe preeclampsia (p>0.05). Comparing laboratory parameters showed significant differences in the laboratory characteristics of hemoglobin (28.57% vs 2.2%, p=0.03) and platelets (33.33% vs 4.54%, p=0.02).Conclusion: Our study showed that the clinical characteristics and disease severity were not significantly different. Laboratory markers correlate significantly with the severity of maternal disease, so they can be used as prognostic indicators.Perbandingan Karakteristik Klinis Ibu Hamil Terkonfirmasi Covid- 19 dengan dan Tanpa Preeklamsia BeratAbstrakLatar Belakang: Beberapa studi klinis telah melaporkan bahwa Infeksi COVID-19 dikaitkan dengan peningkatan risiko preeklamsia dan sindroma yang mirip preeklamsia pada wanita hamil yang terinfeksi, tetapi hasilnya masih kontroversial. Penelitian ini bertujuan untuk mengetahui perbandingan karakteristik klinis ibu hamil yang terkonfirmasi COVID-19 dengan dan tanpa preeklamsia berat.Metode: Penelitian secara retrospektif pada ibu hamil positif COVID-19 ini dilakukan di RSUP Dr. Hasan Sadikin dari tanggal 1 April 2020 sampai dengan 30 April 2022. Data berupa epidemiologi, gambaran klinis, hasil laboratorium subjek dengan dan tanpa preeklamsia berat pasien hamil COVID-19 dikumpulkan dan dianalisisHasil: Data yang berhasil dikumpulkan dalam penelitian ini adalah delapan puluh enam subjek yang terbagi atas 42 subjek dengan preeklamsia berat dan 44 subjek tanpa preeklamsia berat. Usia rata-rata ibu dalam penelitian ini 26 tahun, dengan proporsi yang lebih signifikan pada usia kehamilan cukup bulan. Proporsi primigravida dengan preeklamsia berat lebih signifikan dibandingkan dengan tanpa preeklamsia berat (71.42% vs 29.54%, p=0.02). Tidak ditemukan perbedaan signifikan pada keparahan klinis di antara pasien dengan atau tanpa preeklamsia berat (p>0.05). Perbandingan parameter laboratorium didapatkan perbedaan signifikan pada karakteristik laboratorium hemoglobin (28,57% vs 2.2%, p=0.03) dan trombosit (33.33% vs 4,54%, p=0.02).Kesimpulan: Penelitian ini menunjukkan bahwa karakteristik klinis dan keparahan penyakit tidak berbeda secara signifikan pada kedua pasien. Penanda laboratorium berkorelasi signifikan dengan tingkat keparahan penyakit ibu sehingga dapat digunakan sebagai indikator prognostik.Kata kunci: COVID-19, Karakteristik Klinis , Kehamilan, Preeklamsia Berat
Vaginoplasty and Fimbrioplasty on Vaginal Agenesis with Hematocolpos, Hematometra, and Hematosalpinx Reswari, Arnova; Putri, Delima Istio Prawiradhani; Sasotya, RM Sonny
Jurnal Kesehatan Andalas Vol. 14 No. 3 (2025): November 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v14i3.2645

Abstract

Congenital vaginal agenesis is a rare abnormality of the female genital tract caused by abnormal embryological development of the Müllerian ducts. Clinical manifestations vary depending on the extent of the anomaly, severity, and the patient's age at presentation. It has been reported that a 16-year-old presented to the Urogynecology Clinic at Dr. Hasan Sadikin General Hospital, Bandung, with a chief complaint of cyclic abdominal pain that had been intermittent for the past 2 years and no history of menstruation. The patient was referred from several private hospitals with a history of previous exploratory laparotomies. The girl had normal secondary sexual development. No vaginal sac was found on pelvic examination. A hematocolpos measuring 10.08 x 6.80 x 6.02 cm and a hematometra measuring 14.41 x 12.92 x 10.62 cm were found on ultrasound. An exploratory laparotomy revealed bilateral hematosalpinx with a normal uterus. Vaginoplasty, bilateral partial salpingectomy, and bilateral fimbrioplasty were performed. In this case report, the authors successfully performed vaginoplasty and fimbrioplasty to evacuate the hematocolpos, hematometra, and hematosalpinx. Vaginal molding was then inserted into the neovaginal to prevent spontaneous vaginal collapse and maintained in situ for 2 weeks after surgery. Keywords:  hematocolpos, hematometra, hematosalpinx, vaginal agenesis
Comparison of Quality of Life and Sexual Function between Pelvic Organ Prolapse Patients Using Pessary and Surgical Intervention Nurtanio, Setyawan; Sasotya, RM Sonny; Sukarsa, M. Rizkar Aref; Achmad, Eppy Darmadi; Rinaldi, Andi; Ma'soem, Aria Prasetya; Praharsini, Kania
Indonesian Journal of Obstetrics & Gynecology Science Volume 9 Number 1 March 2026
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v9i1.1035

Abstract

Objective: This study aims to compare the improvement in QoL (measured by PFDI-20) and sexual function (measured by FSFI) in POP patients (stage II-IV) treated with either surgical intervention or pessary insertion.Methods: The study employed a quasi-experimental pre–posttest design involving 60 patients with stage II–IV pelvic organ prolapse (POP), consisting of 30 patients in the surgical group and 30 patients in the pessary group, conducted at two tertiary referral hospitals in Bandung. Quality of life and sexual function were assessed using the Pelvic Floor Distress Inventory-20 (PFDI-20) and the Female Sexual Function Index (FSFI) before and three months after the intervention. Statistical analyses included paired t-tests to evaluate within-group changes before and after the intervention and independent t-tests to compare post-intervention outcomes between the two groups.Results: The results demonstrated that both the surgical group and the pessary group showed significant improvements in quality of life and sexual function (p<0.001). In the surgical group, the FSFI score increased from 16.46 ± 6.88 to 27.68 ± 3.17, surpassing the threshold for normal sexual function, while the PFDI-20 score decreased from 114.34 ± 57.44 to 14.93 ± 7.37. The pessary group also showed significant improvement, with the FSFI score increasing from 18.69 ± 4.76 to 24.80 ± 3.83 and the PFDI-20 score decreasing from 130.24 ± 48.80 to 36.98 ± 21.37. Post-intervention comparative analysis showed statistically better outcomes in the surgical group for both the FSFI score (p=0.002) and the PFDI-20 score (p<0.001).Conclusion: Both surgical and pessary interventions are effective in improving the quality of life and sexual function in women with pelvic organ prolapse. Surgical intervention, however, offers superior and lasting outcomes. Pessary usage remains an important non-surgical option for patients seeking conservative management. AbstrakTujuan: Penelitian ini bertujuan membandingkan perubahan kualitas hidup dan fungsi seksual pada pasien POP stadium II–IV yang menjalani terapi bedah dan penggunaan pessarium.Metode: Metode penelitian yang digunakan yaitu kuasi-eksperimental dengan desain pre–posttest yang dilakukan pada 60 pasien POP stadium II–IV, terdiri atas 30 pasien kelompok bedah dan 30 pasien kelompok pessarium, di dua rumah sakit rujukan tersier di Bandung. Penilaian kualitas hidup dan fungsi seksual dilakukan menggunakan kuesioner Pelvic Floor Distress Inventory-20 (PFDI-20) dan Female Sexual Function Index (FSFI) sebelum dan tiga bulan setelah intervensi. Analisis statistik menggunakan uji t berpasangan untuk menilai perubahan sebelum dan sesudah intervensi pada tiap-tiap kelompok serta uji t tidak berpasangan untuk membandingkan luaran pascaintervensi antar kelompok.Hasil: Hasil penelitian menunjukkan bahwa kelompok dengan terapi bedah dan kelompok dengan pessarium menunjukkan peningkatan bermakna pada kualitas hidup dan fungsi seksual (p<0,001). Pada kelompok bedah, skor FSFI meningkat dari 16,46 ± 6,88 menjadi 27,68 ± 3,17, melewati ambang fungsi seksual normal, sedangkan skor PFDI-20 menurun dari 114,34 ± 57,44 menjadi 14,93 ± 7,37. Kelompok pessarium juga menunjukkan perbaikan yang bermakna, dengan peningkatan skor FSFI dari 18,69 ± 4,76 menjadi 24,80 ± 3,83 dan penurunan skor PFDI-20 dari 130,24 ± 48,80 menjadi 36,98 ± 21,37. Analisis perbandingan pascaintervensi menunjukkan hasil yang secara statistik lebih baik pada kelompok bedah baik untuk skor FSFI (p=0,002) maupun PFDI-20 (p<0,001).Kesimpulan:Terapi bedah dan penggunaan pessarium secara bermakna meningkatkan kualitas hidup dan fungsi seksual pada pasien prolaps organ panggul. Terapi bedah memberikan perbaikan yang lebih besar dan lebih menyeluruh, sedangkan penggunaan pessarium tetap merupakan pilihan nonbedah yang efektif dan aman pada pasien terpilih.