Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
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All Journal Indonesian Journal of Global Health research
Sutiajaya, Nikita Lestari
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Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health

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The Role of Vitamin D in Type 1 and Type 2 Diabetes Mellitus Sutiajaya, Nikita Lestari
Indonesian Journal of Global Health Research Vol 6 No S5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS5.4718

Abstract

Vitamin D deficiency has been associated with decreased insulin release, insulin resistance, and type 2 diabetes in experimental and epidemiological studies. Animal studies have shown that 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) stimulates pancreatic cells to secrete insulin. Genetic polymorphisms of vitamin D-related genes may predispose to impaired glycemic control and type 2 diabetes. The aim of this study was to determine the causality of vitamin D to type 2 diabetes. The method used was to search for articles and theories related to vitamin D and diabetes mellitus. Epidemiological studies have shown an association between low serum 25-hydroxyvitamin D3 (25(OH)D3) concentrations and an increased risk of metabolic syndrome and type 2 diabetes. This may be partly explained by increased fat mass. The results of the search for theories and articles indicate that a possible causal relationship between vitamin D deficiency and type 2 diabetes must be proven by randomized clinical trials showing that type 2 diabetes can be prevented or that insulin release and insulin sensitivity can be improved by vitamin D supplementation.
The Role of Vitamins, Minerals, and Nutrition in Leprosy Patients: A Review Wijaya, Edward; Sutiajaya, Nikita Lestari; Rusyati, Luh Made Mas
Indonesian Journal of Global Health Research Vol 6 No S5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS5.4720

Abstract

Leprosy, is a chronic infectious disease caused by Mycobacterium leprae, an airborne intracellular bacillus and is considered a disease of poverty. Leprosy, with its associated physical and social morbidity, results in economic conditions that lead to malnutrition. The purpose of this study was to explore the role of vitamins, minerals, and nutrition in leprosy patients. The method used in this study was to explore articles and theories related to vitamins, minerals, nutrition and leprosy patients. The results of this study are that decreased antioxidant levels can lead to increased oxidative stress and complications of infectious diseases and leprosy. Because these nutrients have regulatory effects on innate and adaptive immune responses, a perfect balance in their concentrations is important to improve the immune response to pathogens.
Co-Authors Edward Wijaya, Edward Luh Made Mas Rusyati