Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal JPBIO (Jurnal Pendidikan Biologi) Proceeding Biology Education Conference
Soendoess, Khadizah
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Education Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
In silico analysis: Activity of active compounds in passiflora foetida to diabetes Soendoess, Khadizah; Hernawati, Diana; Putra, Rinaldi Rizal
JPBIO (Jurnal Pendidikan Biologi) Vol 9, No 1 (2024): April 2024
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v9i1.2974

Abstract

Plants contain good compounds that are simple to complex including medicinal plants. Herbs are all plant species that are around settlements, cultivated, wild plants that are known to have medicinal properties. An example is the rambusa plant (Passiflora foetida L.). Rambusa leaves are efficacious in relieving fever, insomnia, colds, headaches, diabetes, and asthma. The purpose of this study is to find out physicochemical & pharmacokinetic predictions, toxicity levels, and the affinity of active compounds and a comparison of toxicity levels and affinity of rambusa plants or Passiflora foetida L. with metformin. The method used in this study is qualitative descriptive. Molecular docking with in silico  approach between active compound Passiflora foetida L. with target protein Alpha-glucosidase subunit B to inhibit blood sugar levels (diabetes). The compound that has the best pharmacokinetic profile compared to metformin is Passifloricin A. 5-Hydroxy-7,4'-dimethoxyflavone, Deidaclin, Linamarin, Volkenin, (1S,4S)-Tetraphyllin B (S)-Tetraphyllin A and Passifloricin A compounds are relatively safer, not mutagen and not toxic to the liver, except Passifloricin A is toxic to the liver, because the compound has a safer level of toxicity compared to the comparison medicine, metformin.
Morfologi dan Distribusi Anaphalis javanica (Astreacea) Di Gunung Galunggung Kabupaten Tasikmalaya Soendoess, Khadizah; Izmiati, Indri Izni; Hendrawan, Al Maidah; Sofia, Ismi Daru; Gina, Salwa Alya; Putra, Rinaldi Rizal
Proceeding Biology Education Conference: Biology, Science, Enviromental, and Learning Vol 19, No 1 (2022): Proceeding Biology Education Conference
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mount Galunggung is one of the icons of natural tourism located in Tasikmalaya Regency. The natural beauty that stores various flora and fauna is one of the attractions for people visiting Mount Galunggung. One type of flora found on Mount Galunggung is the edelweiss flower (Anaphalis javanica), which can still be found relatively in the canyon area or the crater rim of Mount Galunggung. Along with the increasing number of tourists visiting Mount Galunggung, A. javanica has been significantly exploited because of the factors taken by tourists. Therefore, this study aimed to determine the morphological characteristics and distribution of edelweiss (A. javanica) in Mount Galunggung, Tasikmalaya Regency. The method used in this research is the descriptive quantitative survey technique. The variables in this study include the morphology and distribution of edelweiss (A. javanica). The study location was in the canyon area of Mount Galunggung, at an altitude of 1,000 – 1,150 meters above sea level. The sampling technique used is purposive sampling with the consideration of locations that are overgrown by edelweiss (A. javanica). The line transect method measuring 2 x 2 m with a transect length of 50 meters was used to obtain distribution data. To obtain morphological data, the key to determining and identifying plant parts was used to van Steenis. The distribution pattern data was processed using the Morisita Index. The results showed that the morphological character of edelweiss in Mount Galunggung refers to the character of Anaphalis javanica, so it is inevitable that the species is Anaphalis javanica. Next, the distribution pattern of A. javanica found in Mount Galunggung is included in the random category, with the Morisita distribution index value of 0.36.
Co-Authors Gina, Salwa Alya Hendrawan, Al Maidah Hernawati, Diana Izmiati, Indri Izni Rinaldi Rizal Putra, Rinaldi Rizal Sofia, Ismi Daru