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All Journal World Psychology Research of Scientia Naturalis Journal of Biomedical and Techno Nanomaterials
Hamdan, Salma
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Physics Social Sciences Other

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Effectiveness of Anti-Bullying Program in Enhancing Positive School Climate in Middle Schools Imha, Ulia Arbarehan; Al-Momani, Ammar; Hamdan, Salma
World Psychology Vol. 4 No. 1 (2025)
Publisher : Sekolah Tinggi Agama Islam Al-Hikmah Pariangan Batusangkar, West Sumatra, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55849/wp.v4i1.803

Abstract

Bullying in schools is a pervasive issue that negatively impacts students’ mental health, academic performance, and overall school climate. A positive school climate is essential for fostering an environment conducive to learning, where students feel safe, respected, and supported. Anti-bullying programs have been implemented to address this problem; however, their effectiveness in enhancing school climate, particularly in middle schools, remains underexplored. This study aims to evaluate the effectiveness of an anti-bullying program in improving the school climate in middle schools. The research utilizes a quasi-experimental design, with 300 students from three middle schools participating in the study. Pre- and post-program surveys were administered to assess students’ perceptions of school climate, including safety, respect, and inclusiveness. The results indicate a significant improvement in the overall school climate, with increased perceptions of safety and respect, and a reduction in bullying behaviors. Students reported feeling more supported and engaged in the school community after the program. The study concludes that anti-bullying programs can be highly effective in fostering a positive school climate, providing a safer and more supportive environment for students. The findings suggest that implementing such programs in middle schools can significantly contribute to improving the educational experience and well-being of students.
The Role of Epigenetics in Plant Adaptation to Environmental Stress Hamdan, Salma; Al-Fayez, Mazen; Chahine, Alaa
Research of Scientia Naturalis Vol. 2 No. 1 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/scientia.v2i1.2003

Abstract

Epigenetics plays a crucial role in how plants adapt to environmental stressors such as drought, salinity, and extreme temperatures. Understanding the mechanisms behind epigenetic modifications can provide insights into plant resilience and survival strategies in changing environments. This study aims to investigate the role of epigenetic mechanisms in plant adaptation to various environmental stressors. By examining specific epigenetic modifications and their effects on gene expression, the research seeks to elucidate the pathways through which plants respond to stress. A combination of field experiments and laboratory analyses was employed to study epigenetic changes in selected plant species exposed to different environmental stress conditions. Techniques such as DNA methylation profiling and histone modification analysis were utilized to assess epigenetic alterations. Findings indicate that epigenetic modifications, including changes in DNA methylation and histone acetylation, play a significant role in regulating gene expression in response to stress. Certain stress-induced epigenetic changes were associated with enhanced tolerance to adverse conditions, suggesting a vital adaptive mechanism for plants. This research highlights the importance of epigenetics in understanding plant adaptation to environmental stress. The findings contribute to the growing body of knowledge regarding plant resilience mechanisms and may inform breeding programs aimed at developing stress-tolerant plant varieties
Immunomodulation Mechanism by Gold Nanoparticles for Cancer Therapy Hamdan, Salma; Al-Khouri, Bassam; Hariri, Rami
Journal of Biomedical and Techno Nanomaterials Vol. 2 No. 2 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v2i2.2024

Abstract

Conventional cancer treatment is often limited by side effects and resistance to therapy. Therefore, immunotherapy research, especially those involving gold nanoparticles (AuNPs), is growing as a more effective and specific therapeutic alternative. AuNPs have the potential to modulate the body's immune response, improving the recognition and destruction of cancer cells by the immune system. This study aims to investigate the immunomodulation mechanisms triggered by AuNPs and evaluate their potential as cancer therapeutic agents by increasing immune cell activity and cytokine production. This study used cell culture to test the effects of AuNPs on the activity of T cells, macrophages, and dendritic cells as well as the production of cytokines IL-2, TNF-?, and IL-12. Gold nanoparticles were applied at various concentrations (5, 10, 20 ?g/ml) and treatment times (24, 48, 72 hours), then measured using flow cytometry and ELISA. The results showed that AuNPs increased the activity of immune cells, especially dendritic cells, macrophages, and T cells, as well as the production of cytokines IL-2, TNF-?, and IL-12. This increase in immune cell and cytokine activity is directly related to the concentration and duration of AuNPs treatment. This study shows that AuNPs can modulate the body's immune system and increase the immune response to cancer. Gold nanoparticles have the potential as immunomodulatory agents in more effective and safe cancer therapy. More research is needed to confirm these findings in animal and human models.
Co-Authors Al-Fayez, Mazen Al-Khouri, Bassam Al-Momani, Ammar Chahine, Alaa Hariri, Rami Imha, Ulia Arbarehan