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The Effect Of Topical Robusta Coffee Extract (Coffea Robusta) In Accelerating The Healing Process Of Cuts In The Backs Of White Wistar Rats (Rattus Norvegicus) Aditya Wardhana; Xavier Ongko, Nicolas; Samin, Buter; Diana Putri, Lenni
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Abstract

The purpose of this study was to test the research hypothesis, namely whether topical administration of coffee extract affects the acceleration of the healing process of cuts on the backs of rats. Based on the results of the research that has been done, it can be concluded that the administration of the Robusta coffee extract (Coffea Robusta) can accelerate the healing of cuts in white Wistar rats, which is characterized by an average difference in the percentage of the recovery. However, after the T-test, the results obtained for H0 were rejected, meaning there was no significant difference between the control group, which was only given 0.9% NaCl and the treatment group, which was given Robusta coffee extract. Topical can accelerate wound healing. The results of this study are expected to be suggestions and references for other researchers who wish to study the use of Robusta coffee extract in understanding the healing process of cuts.
THE RELATIONSHIP OF THE NUMBER OF NEUTROFIL LYMPHOCYTE RATIO WITH THE PICTURE OF COLITIS Br Tarigan, Agita Angela; Xavier Ongko, Nicolas; Edlin, Edlin
Jurnal Impresi Indonesia Vol. 3 No. 2 (2024)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v2i12.4037

Abstract

Colitis is an acute or chronic inflammation of the colon. The gold standard for diagnosis and monitoring of disease activity in colitis patients is endoscopy combined with pathology biopsy. However, endoscopy has disadvantages related to invasiveness, cost, and feasibility of use for long-term follow-up. The neutrophil-lymphocyte ratio is a simple biomarker that can serve as a useful biomarker for diagnosing and predicting mucosal inflammation in colitis. This study aims to determine whether there is an influence between the number of neutrophil-lymphocyte ratios and the appearance of colitis. This research is a cross-sectional observational analytical research. In this study, 44 medical record data were used. A total of 44 colitis medical record data for the 2022-2023 period were collected. The largest age group is 61-70 years with 11 people (25%), based on the gender group the largest is male with 30 people (68.2%), and based on histopathology the largest is 25 (56.8%) patients. who suffers from chronic colitis. However, in the study, there was no relationship between the neutrophil-lymphocyte ratio and the appearance of colitis, P = 0.22 (P value> 0.05) and the Prevalence Ratio 95% CI 1,436 (0,832-2,476). Based on the results of this study, the majority of patients are male, based on the patient's age, the majority is between 61-70 years, and based on the histopathology picture, the majority is chronic colitis. However, in the study, there was no relationship between the neutrophil-lymphocyte ratio and the appearance of colitis, P = 0.22 (P value > 0.05), and the 95% Prevalence Ratio was 1,436 (0,832-2,476).