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All Journal Journal of Agropharmacy
Syafika, Devina Sarah
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Biochemistry, Genetics & Molecular Biology

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Baricitinib for the treatment of COVID-19 Firdha Aprillia Wardhani; Syafika, Devina Sarah; Kusumaningrum, Yunita Dyah; Adelia Firandi
Journal of Agropharmacy Vol. 1 No. 2 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/joa.v1i2.1422

Abstract

Baricitinib which is one of the therapies for rheumatoid arthritis is a JAK inhibitor. WHO recommended therapy with the combination of baricitinib and corticosteroids in COVID-19 patients with severe or critical condition. Effectivity and safety assessment of Baricitinib use were carried out by reviewing the literature published between December 2019 – February 2022, and showed that the use of Baricitinib in COVID-19 patients resulted in an improvement of lung function, improvement of oxygen saturation, higher recovery rate, and lower mortality, with similar adverse event incidence. A loading dose or a higher dose can be recommended for patient with caution and consideration of higher possibility in the incidence of adverse events
Co-Authors Adelia Firandi Wardhani, Firdha Aprillia