Nydia Hanan
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Oral Manifestation of Papillon-Lefevre in Two Siblings Nydia Hanan; Satiti Kuntari; Els Sunarsih Budipramana
Denta Journal Kedokteran Gigi Vol 17 No 2 (2023): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v17i2.6

Abstract

Background: Papillon-Lefèvre Syndrome (PLS) is a very rare genetic disorder (autosomal recessive) that usually affects infants between the ages of one and five years. PLS is characterized by palmar-plantar hyperkeratosis and premature loss of primary and permanent teeth with extensive, severe, and rapid destruction of the alveolar bone, leading to the premature loss of both teeth. Objective: To report on the management of PLS patients. Case: A 9-year-old girl and a 2.5-year-old boy from Nganjukto General Hospital, Pediatric Dentistry Division, RSGM Airlangga University with the main complaints of upper left tooth pain, rocking, difficulty eating, erythematous hyperkeratosis hands and feet, periodontal inflammation, mobility. bad teeth. Case Management: Nine-year-old girl: Teeth #26 and #46 could not be retained and extracted due to buccoversion and severe mobility. Periodontal supportive therapy was periodontal debridement, scaling and root planing and oral hygiene counseling with 0.20% chlorhexidine gluconate. Two-and-a-half-year-old boy: Too young, he is observed every 3 months. It is recommended to take vitamin B complex in appropriate doses and fruit juice as an additional supplement. Conclusion: Intensive periodontal treatment and administration of antibiotics only delays the progression of periodontal disease and cannot be used to prevent primary and permanent teeth. Extensive and repeated prosthodontic treatment is required to provide functional teeth to children during their period of jaw growth.
Karakteristik Pasien Leukemia Dengan Manifestasi Oral di RSUD Abdoel Wahab Sjahrani Samarinda Nydia Hanan; Annisa Muhyi; Muhammad Buchori; Amalia Aswin; Aulya Rahma Fadilah; Ranya Olivia
Denta Journal Kedokteran Gigi Vol 18 No 2 (2024): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v18i2.2

Abstract

Background: Leukemia is a common malignancy in children and occurs when changes in normal cell regulatory processes lead to proliferation of hematopoietic stem cells. Leukemic patients have a higher susceptibility to dental and oral diseases such as mucositis and xerostomia due to damage by chemotherapeutic agents to oral mucosal cells which have a high mitotic index. Objective: To determine the characteristics of leukemia in children with oral manifestations at the Abdoel Wahab Sjahranie Hospital Samarinda which is the main referral hospital in the province of East Kalimantan. Materials and Methods: This research is descriptive with cross-sectional method using medical record data as the subject based on the specified criteria. Data were grouped by type of leukemia, age, gender, nutritional status and oral manifestations. Results: A total of 1,330 cases of Leukemia in 2017-2021 with 12 suitable respondents. There were cases with male gender (58.3%) and 0-5 years of age which were comparable to those of 6-18 years (50%). The type of acute lymphoblastic leukemia was the most common in this study with a frequency of 83.3%. Mucositis (58.3%) was the most common manifestation of people with normal nutritional status (41.7%) and laboratory results stated the average of leukocytes was 45,700/uL, hemoglobin was 10.4 g/dl, and platelets was 117,600/mm3. A total of 66.6% of respondents had received chemotherapy. Conclusion: Oral manifestations can occur due to leukemia or side effects of chemotherapy, the importance of multidisciplinary and comprehensive treatment between pediatricians and pediatric dentists in managing the dental health of leukemia patients.