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All Journal Pharmaqueous Jurnal Laboratorium Khatulistiwa
Wijayanti, Faulia Triana
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Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Formulasi Dan Evaluasi Nanoemulsi Minyak Ikan Sidat Menggunakan Metode Sonikasi Az-Zahra, Adilla Putri; Wijayanti, Faulia Triana; Ramadhanti, Lailiya
Pharmaqueous: Jurnal Ilmiah Kefarmasian Vol. 4 No. 2 (2022): Volume 4, Nomor 2, November 2022
Publisher : Universitas Al-Irsyad Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v4i2.302

Abstract

Nanoemulsi merupakan salah satu bentuk sediaan yang stabil, transparan dan memiliki ukuran droplet yang sangat kecil biasanya di kisaran 20-200 nm. Nanoemulsi dibuat dengan mencampur fase minyak dan fase air dengan bantuan surfaktan dan kosurfaktan untuk menurunkan tegangan antarmuka. bermanfaat bagi kesehatan. Omega-3 merupakan salah satu asam lemak tak jenuh yang esensial bagi tubuh dan dibutuhkan terutama bagi penderita kolesterol tinggi, EPA dan DHA merupakan jenis omega-3 yang paling dominan pada minyak ikan. Bahwa Ikan sidat dari hasil budidaya yang berasal dari daerah Cilacap (Indonesia) dengan berat rata- rata 300 g/ekor mengandung protein 17,51 %, lemak 17,72 %, kadar air 62,36 % dan kadarabu 1,33 %.
In Vitro Anti-Biofilm Activity of Nutmeg (Myristica fragrans) Leaf Infusion Extract Wijayanti, Faulia Triana; Nugroho, Yusuf Eko; Pangesti, Ira
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2097

Abstract

Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium commonly associated with severe infections, particularly in immunocompromised individuals. One of its major virulence factors is biofilm formation, which contributes to increased antimicrobial resistance. This study aimed to evaluate the inhibitory activity of nutmeg (Myristica fragrans) leaf infusion extract against P. aeruginosa biofilm formation in vitro. The experiment was conducted using a 96-well microtiter plate assay, and biofilm intensity was quantified at 595 nm following crystal violet staining. The results demonstrated that the nutmeg leaf infusion extract significantly inhibited biofilm formation, with varying levels of effectiveness depending on incubation time. These findings indicate the potential of nutmeg leaf infusion extract as an antibiofilm agent against P. aeruginosa.
Co-Authors Az-Zahra, Adilla Putri Nugroho, Yusuf Eko Pangesti, Ira Ramadhanti, Lailiya