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Journal : Open Access DRIVERset

Determine the Background Characteristics of Abattoir Butchers in Sishiagu, Tamale Metropolis Asare, Solomon Ossom; Bulama, Ahmed Abdu; Udoh, Mary Athanasius; Tahidu, Issifu
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 2 No 1 (2025): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v2i1.5025

Abstract

This study aimed to determine the background characteristics of abattoir butchers in Sishiagu, Tamale Metropolis. A total of two hundred structured questionnaires were used to collect data on participants' background characteristics of abattoir butchers, and data analysis was performed using SPSS version 21. The results showed that all butchers (95.5%) in this study were male, while 4.5% with 20.7% aged less than 20yrs 43.7% between 20yrs and 30 yrs, 25.9% 31yrs to 40yrs, 7.4% 41yrs to 50yrs and 2.2% 51yrs to 60yrs, less than half (43.7%) of the butchers were older than 29yrs. Additionally, 61.9% of butchers were married, while 36.6% were single and Divorced was 1.5%. The study found that 46% had less than 10 years of work experience, while 24% had 11 to 20 years of experience. Notably, 20.7% of butchers were uneducated, with only 0.7% with postgraduate, 5.9% holding a university degree, 26.7% with SSS/SHS and 20.7% with JHS. Furthermore, tenure of years in the business was found to be 30.4% at the age of 1yrs to 5yrs, 35.6% at 6yrs to 10yrs and 34.1 % at 11yrs. There was a clear understanding that younger generation at the age of 20yrs to 40yrs is taking over the Abattoir Butchers. In conclusion, the study indicates that the work force in the abattoir are younger generation based on the background characteristics and as such a moderate awareness regarding meat hygiene among butchers and meat workers in Sishiagu, Tamale Metropolis should be obtainable.
Estimation of Kidney Function and Haematological Parameters of Methanol Leaf Extract of Annona senegalensis on Diethyl Nitrosamine-Induced Hepatocellular Carcinoma in Rats Umaru, Isaac John; Absalom, Augustine; Udoh, Mary Athanasius; Omolara, Mosugu Ovayoza; Okang, Ogar Fonne; Akem, Ingwu Joseph; Tansaba, Akafa Andes; Frank, Otashu Kenneth; Philip, Shadrach
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 2 No 3 (2025): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v2i3.7359

Abstract

Hepatocellular carcinoma (HCC) is a major cause of liver-related mortality worldwide, often linked to oxidative stress and hepatotoxicity induced by carcinogens such as diethylnitrosamine (DEN). This study investigates the biochemical and hematological effects of methanol leaf extract of Annona senegalensis on DEN-induced HCC in male albino rats. Thirty rats were divided into six groups: normal control, negative control (DEN-induced), positive control (DEN + silymarin), and three treatment groups receiving A. senegalensis extract at 200 mg/kg, 400 mg/kg, and a combined regimen. DEN exposure significantly elevated serum biomarkers of liver damage, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and bilirubin. Treatment with A. senegalensis extract at 400 mg/kg markedly reduced ALT, AST, and ALP levels compared to the negative control, demonstrating hepatoprotective potential. Hematological analysis revealed a decline in white blood cell (WBC) count across treatment groups, suggesting possible immunosuppressive effects. Red blood cell (RBC) count and hemoglobin (HGB) levels decreased at 200 mg/kg but increased at 400 mg/kg, indicating a dose-dependent erythropoietic effect. Platelet (PLT) counts, elevated in the DEN-induced group, were normalized by the extract. These results suggest that A. senegalensis contains bioactive compounds with hepatoprotective and hematomodulatory activities. While higher doses improved liver function and hematological balance, the observed immunosuppressive tendencies highlight the need for further mechanistic studies. The findings support the therapeutic potential of A. senegalensis in hepatocellular carcinoma management, warranting future preclinical and clinical evaluation.