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All Journal JOURNAL LA MEDIHEALTICO Innovative: Journal Of Social Science Research
Damopolii, Suciati
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Humanities Computer Science & IT Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary Other

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Literatur Review : Analisis Faktor Pembekuan Darah dan Gambaran Radiologi pada Pasien Covid 19 Basri, Hasri Ainun; Syahril, Erlin; Damopolii, Suciati; Damopolii; Kamaluddin, Irna Diyana Kartika
Innovative: Journal Of Social Science Research Vol. 4 No. 5 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i5.14944

Abstract

COVID-19 is a contagious illness caused by a newly identified coronavirus, Sars-Cov 2 (Severe Acute Respiratory Syndrome Coronavirus 2), which was identified in 2019. Thrombocytopenia, increased D-dimer, delayed prothrombin time, and disseminated intravascular coagulation were among the abnormalities of blood clotting factors seen in COVID-19 patients. Increased D-dimer concentrations, slightly reduced platelet counts, and delayed prothrombin time are typical findings in individuals with coagulopathy who are infected with COVID-19. To confirm a diagnosis of COVID-19 in individuals infected with SARS-CoV-2, radiographic tests such CT scans and thoracic photographs are required. Radiological examinations and CT-Scan and thoracic photo which is often found ground glass opacities, crazy-paving, pleural effusion, sub-pleural bands, pulmonary edema, consolidation, reticular opacities and paracardiac atelectasis, traction bronchiectasis and vacuolar signs. This study aims to analyse blood coagulation factors and radiological features in covid 19 patients. A Literature Review with a Narrative Review is the methodology used in this research. Secondary data sourced from electronic sites such as Pubmed, Clinical Key, and Springer Link provide the bulk of this study's data set. Articles were found using the following keywords: COVID-19, radiological imaging, blood clotting factors. In order to address the research issue statement, 20 research papers were chosen from the scope literature. Radiological imaging and blood clotting factors in COVID-19 patients were reported in 20 separate investigations. The review's findings suggest that radiographic exams for coagulation abnormalities and ground glass opacities are common in individuals with severe COVID-19 infection.
Vitamin E Supplementation and Its Impact on Pulmonary Tuberculosis Treatment Outcomes: A Systematic Review Basir, Adhelia Zalsabilah; Wiriansya, Edward Pandu; Damopolii, Suciati; Hasan, Hasan; Kanang, Indah Lestari Daeng
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2776

Abstract

Pulmonary tuberculosis remains a global health problem, and antioxidant deficiencies such as vitamin E contribute to increased oxidative stress in patients. The aim of this study was to assess the effect of vitamin E supplementation on the effectiveness of pulmonary tuberculosis treatment through a systematic review based on PRISMA 2020 guidelines. This systematic review included clinical and observational studies investigating the relationship between vitamin E and pulmonary tuberculosis. Literature searches were conducted in PubMed and Google Scholar (2008–2021) using the keywords “Vitamin E,” “Tuberculosis,” and “Lung.” Methodological quality was assessed using the JBI Checklist and Cochrane RoB2. The process was carried out at the Faculty of Medicine, Muslim University of Indonesia, Makassar, from March to August 2024. Secondary data from published studies were used; therefore, ethical approval was not required. Six studies met the inclusion criteria, consisting of two randomized controlled trials, two in vitro studies, one case–control study, and one cross-sectional study. The synthesis results showed that vitamin E supplementation consistently reduced oxidative stress, as indicated by a significant decrease in malondialdehyde (MDA) levels and an increase in enzyme activity. In addition, vitamin E improved inflammatory status through reduced C-reactive protein (CRP) levels and increased serum leptin, as well as enhanced cellular immune responses through elevated IL-2 and IFN-γ levels. Overall, vitamin E supplementation contributed to improved treatment effectiveness and quality of life in patients with pulmonary tuberculosis.Vitamin E supplementation has potential as an adjuvant therapy that enhances the effectiveness of pulmonary tuberculosis treatment through antioxidant and immunomodulatory mechanisms.
Co-Authors Basir, Adhelia Zalsabilah Basri, Hasri Ainun Damopolii Hasan Hasan Kamaluddin, Irna Diyana Kartika Kanang, Indah Lestari Daeng Syahril, Erlin Wiriansya, Edward Pandu