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Pengaruh Anemia dan Preeklampsia terhadap Kejadian Bayi Berat Lahir Rendah (BBLR) Cahyani, Pramesty Regita; Dahliah, Dahliah; Makmun, Armanto; Kamaluddin, Irna Diyana Kartika; Darma, Sidrah
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.131

Anemia and preeclampsia during pregnancy contribute significantly to the risk of low birth weight (LBW) in neonates. Anemia, characterized by hemoglobin levels below 11 g/dL in the first and third trimesters, and below 10 g/dL in the second trimester, and preeclampsia, which involves hypertension and organ dysfunction after 20 weeks of pregnancy, can interfere with the supply of oxygen and nutrients to the fetus, causing LBW. The study conducted a Literature Review of 840 articles, and found that anemia increased the risk of LBW by about 1.49 times, while preeclampsia also had a significant association with LBW. These findings suggest the importance of early detection and treatment of anemia and preeclampsia to improve neonatal health outcomes. Further research is needed to develop more effective interventions to address these conditions.

Hubungan Kehamilan Usia Dini Dengan Kejadian Bayi Lahir Prematur Bali, Andi Azizah Nabila Tenri; Arfah, Arni Isnaini; Kamaluddin, Irna Diyana Kartika; Nulanda, Mona; Darussalam, Andi Husni Esa
Journal of Telenursing (JOTING) Vol 6 No 2 (2024): Journal of Telenursing (JOTING)
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/joting.v6i2.13252

This study aims to determine the relationship between early pregnancy and the incidence of premature births and also the relationship between the incidence of premature births and LBW (Low Birth Weight Babies) in 2019-2023. The method used in this study is quantitative research with a descriptive research design conducted at RSIA Sitti Khadijah 1 Makassar in May 2024. This sample uses total sampling. The results of the study showed that out of 655 samples, 47 samples were taken that met the inclusion criteria, so that from the 47 samples, the prevalence of premature births from early mothers at RSIA Sitti Khadijah 1 Makassar in 2019-2023 was 21.3% for the extreme premature category, 29.8% for the very premature category, and 48.9% for the moderate to late premature category. The prevalence of BBLR (Low Birth Weight Babies) at RSIA Sitti Khadijah 1 Makassar in 2019-2023 was 61.7% for the low birth weight category and 38.3% for the very low birth weight category. The results of the bivariate test of early pregnancy with the incidence of premature birth obtained a p-value of 0.084 and the results of the bivariate test of the incidence of premature birth with BBLR (Low Birth Weight Babies) obtained a p-value of 0.003. The conclusion of this study is that there is no relationship between early pregnancy and the incidence of premature birth. There is a relationship between the incidence of premature birth and BBLR (Low Birth Weight Babies). Keywords: BBLR (Low Birth Weight Babies), Early Pregnancy, Incidence Of Premature Birth

The Relationship of Neoadjuvant Taxanes, Anthracyclines, Cyclophosphamide Chemotherapy on Nutritional Status Based on Body Mass Index (BMI) and Albumin Measurements in Locally Advanced Stage Breast Cancer Patients in Bahteramas Hospital Kendari S Limba, Afirah Khairunnisa; Royani, Ida; Muchsin, Achmad Harun; Kamaluddin, Irna Diyana Kartika; Irsandy, Febie
Indonesian Journal of Cancer Vol 18, No 4 (2024): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i4.1283

Background: Breast cancer is a disease caused by cancer cells in breast tissue. The most frequently found is locally advanced. The locally advanced stage refers to stages IIIA, IIIB, and IIIC. Neoadjuvant is the treatment for locally advanced. The Taxane, Anthracycline, and Cyclophosphamide (TAC) is a neoadjuvant chemotherapy regimen that can cause nausea and vomiting resulting in decreased appetite and lack of nutritional intake in patients. This study aims to determine the relationship between neoadjuvant TAC chemotherapy and nutritional status based on measurements of BMI and albumin in breast cancer patients at Bahteramas Kendari Hospital.Method: This study was conducted with a retrospective cross-sectional design. The sampling technique was consecutive sampling using 41 medical records of breast cancer patients from the years 2023 to 2024 in Bahteramas Kendari Hospital.Result: There were significant changes in the nutritional status of patients who received neoadjuvant TAC chemotherapy. Before chemotherapy, the patient’s BMI was found to be in the normal category of 34.1% and decreased to 31.7% after chemotherapy. Likewise, patients with obesity were 34.1% before chemotherapy and changed to 19.5% after chemotherapy. Furthermore, there were significant changes in the patient’s albumin levels. Before chemotherapy, 38 patients had normal albumin levels (92.7%), whereas after chemotherapy only 24 patients had normal albumin levels (58.5%).Conclusion: There was a relationship between TAC neoadjuvant chemotherapy and nutritional status based on BMI and Albumin measurements before and after chemotherapy in patients with locally advanced breast cancer.

Uji Efektivitas Ekstrak Etanol Serai (Cymbopogon Citratus) Terhadap Kadar Low Density Lipoprotein pada Tikus Putih Dengan Obesitas Assofi, A. Syarifah Balqis; Hidayati, Prema Hapsari; Irmayanti; Kamaluddin, Irna Diyana Kartika; Mulyadi, Farah Ekawati
Borneo Journal of Medical Laboratory Technology Vol. 7 No. 2 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v7i2.9398

Peningkatan kadar LDL (Low Density Lipoprotein) berperan signifikan dalam proses aterosklerosis yang mendasari PJK. Tujuan penelitian ini untuk mengetahui pengaruh dari pemberian ekstrak etanol serai (Cymbopogon citratus) terhadap penurunan kadar LDL pada tikus putih yang obesitas. Metode penelitian ini adalah eksperimental dengan pre and post test control group design dengan menggunakan tikus putih (Rattus novergicus) yang obesitas. Hasil pada uji normalitas pada penelitian ini didapatkan data tidak terdistribusi normal sehingga digunakan uji wilcoxon untuk menilai perbandingan kadar LDL sebelum dan sesudah perlakuan. Hasil uji wilcoxon menunjukkan nilai signifikan pada kelompok kontrol positif dengan nilai p 0,043, kelompok ekstrak 150 mg/dl dengan nilai p 0,043, dan kelompok ekstrak 200 mg/dl dengan nilai p 0,042. Pada uji pos hoc mann whitney didapatkan nilai yang signifikan pada perbandingan kelompok kontrol negatif dan ekstrak 200 mg/dl dengan nilai p 0,036. Kesimpulan penelitian ini adalah ekstrak etanol serai dapat dipertimbangkan sebagai alternatif terapi alami dalam mengurangi kadar LDL, terutama pada individu dengan obesitas.

Comparative Analysis of Antioxidants in Moringa Leaves and Soursop Leaves Kamaluddin, Irna Diyana Kartika; Ramadhani, Pratiwi Trisda; Bima, Irmayanti Haidir; Irwan, Andi Alamanda; Matoo, Rasfayanah F.
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.6760

Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so antioxidants function to neutralize free radicals. Antioxidants delay and inhibit cell damage through their properties that can neutralize free radicals. Several studies have reported that M.oleifera has antioxidant activity to various pharmacological effects such as anti-inflammatory and anti-cancer. Moringa oleifera or better known as Moringa is a plant that is widely used by the community to overcome various disease complaints. In addition to Moringa leaves, Soursop leaves (Annona muricata L) also have high antioxidant content in their leaves so that these plants can be divided into synthetic antioxidants and natural antioxidants. The use of synthetic antioxidants is currently decreasing due to consideration of the negative effects on health such as liver damage and can cause carcinogens so that their use is replaced by natural antioxidants. The natural antioxidants in question are compounds found in natural materials such as Moringa leaves and Soursop leaves. The type of research used in this study is experimental research by testing the comparison of antioxidant compound activity between Moringa leaves and Soursop leaves using the DPPH method. Moringa leaves had antioxidant activity of 141.34 ppm, while Soursop leaves had antioxidant activity of 82.39 ppm. There is no significant difference in antioxidant activity between Moringa leaves and Soursop leaves.

Relationship between Nutritional Status and Haemoglobin Level in Students of Senior High School 3 Bone Murfat, Zulfitriani; Rahman, Haryadi; Idrus, Hasta Handayani; Kamaluddin, Irna Diyana Kartika; B, Sri Wahyuni Gayatri
Journal of Aafiyah Health Research (JAHR) Vol. 5 No. 1 (2024): JANUARY-JUNE
Publisher : Postgraduate Program in Public Health, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52103/jahr.v5i1.1584

Abstrak Latar Belakang: Status gizi adalah suatu ukuran mengenai kondisi tubuh seseorang yang dapat dilihat dari makanan yang dikonsumsi dan penggunaan zat-zat gizi dalam tubuh. Ketidakseimbangan antara status gizi dengan kebutuhan tubuh menimbulkan kelainan patologis bagi tubuh. Seperti malnutrisi akibat kurangnya asupan zat gizi sehingga kebutuhan gizi dalam tubuh tidak terpenuhi terutama kebutuhan gizi seperti zat besi. Dimana zat besi adalah salah satu komponen penting dalam pembentukan hemoglobin. Mengacu pada latar belakang tersebut penulis tertarik untuk melakukan penelitian mengenai hubungan status gizi terhadap kadar hemoglobin pada siswa/siswi SMAN 3 Bone. Metode: Metode penelitian ini adalah Observasional analitik. Dengan menentukan status gizi melalui pemeriksaan antropometri IMT dan kadar hemoglobin dengan Easy Touch GCHB. Hasil: Hasil penelitian menunjukkan dari 80 siswa/siswi memiliki status gizi underweight 31,3%, normal 46,3%, overweight 13,8%, obesitas I 7,5%, obesitas II 1,3% sedangkan pada kadar hemoglobin sebanyak 27,5% mengalami anemia dan 72,5% normal. Terdapat hubungan yang bermakna antara status gizi terhadap kadar hemoglobin sebesar 0,003 (p<0,005). Kesimpulan: Terdapat hubungan yang signifikan antara status gizi terhadap kadar hemoglobin pada siswa/siswi SMAN 3 Bone. Abstract Background: Nutritional status is a measure of the condition of a person's body that can be seen from the food consumed and the use of nutrients in the body. The imbalance between nutritional status and body needs causes pathological disorders for the body. Such as malnutrition due to lack of nutrient intake so that nutritional needs in the body are not met, especially nutritional needs such as iron. Where iron is one of the important components in the formation of hemoglobin. Referring to this background, the author is interested in conducting research on the relationship between nutritional status and hemoglobin levels in students of SMAN 3 Bone. Methods: This research method is Observational analytic. By determining nutritional status through anthropometric examination of BMI and hemoglobin levels with Easy Touch GCHB. Results: The results showed that out of 80 students had a nutritional status of underweight 31.3%, normal 46.3%, overweight 13.8%, obesity I 7.5%, obesity II 1.3% while at hemoglobin levels as much as 27.5% were anemic and 72.5% were normal. There is a significant relationship between nutritional status and hemoglobin levels of 0.003 (p<0.005). Conclusion: There is a significant relationship between nutritional status and hemoglobin levels in students of Senior High School 3 Bone.

Identifikasi Morfologi dan Koloni Bakteri Probiotik Pada Makanan Tradisional Dangke: Morphological and Colony Identification of Probiotic Bacteria in Dangke Traditional Food Widyadhana, Narlhiandini Mitresna; Bamahry, Aryanti R.; Kamaluddin, Irna Diyana Kartika; Safitri, Asrini; Mangarengi, Yusriani
Journal of Aafiyah Health Research (JAHR) Vol. 5 No. 1 (2024): JANUARY-JUNE
Publisher : Postgraduate Program in Public Health, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52103/jahr.v5i1.1587

Abstrak Latar Belakang: Dangke merupakan produk olahan susu sapi atau susu kerbau dengan getah papaya yang dibungkus menggunakan daun pisang. Susu merupakan media yang baik untuk perkembangan mikroba karena kandungan nutrisinya yang tinggi dengan aktivitas air yang tinggi pada pH yang mendekati netral. Metode: Penelitian ini merupakan penelitian deskriptif dengan desain eksperimental. Dilakukan perhitungan koloni pada media isolasi dan persentase konsentrasi mikroorganisme serta mengidentifikasi morfologi bakteri Hasil: Dangke susu kerbau segar. Jumlah koloni bakteri pengenceran 10-1 paling banyak terdapat pada dangke 1, dangke 2, dan dangke 5, pengenceran 10-2 paling banyak pada dangke 1, pengenceran 10-3 paling banyak dangke 2, pengenceran 10-4 paling banyak pada dangke 3, pengenceran 10-5 paling banyak pada dangke 3. Persentase konsentrasi dangke 1 (33,3%), dangke 2 (25%), dangke 3 (20%), dangke 4 (20%), dangke 5 (25%). Morfologi bakteri basil dengan jenis bakteri gram positif. Dangke susu kerbau mengandung bakteri probiotik Genus Lactobacillus bermanfaat bagi kesehatan yang bisa membantu proses pencernaan, meningkatkan kekebalan tubuh, dan dapat menghasilkan bakteriosin untuk melawan bakteri patogen. Kesimpulan: Terdapat morfologi bakteri basil dengan koloni streptobasil termasuk jenis bakteri gram positif pada makanan tradisional dangke susu kerbau, yang tergolong bakteri probiotik Genus Lactobacillus. Abstract Background: Dangke is a processed product of cow's milk or buffalo milk with papaya sap wrapped using banana leaves. Milk is a good medium for microbial development due to its high nutritional content with high water activity at a pH close to neutral. Methods: This research is a descriptive study with an experimental design. Calculation of colonies on isolation media and percentage concentration of microorganisms and identifying bacterial morphology were carried out. Results: Fresh buffalo milk dangke. The number of bacterial colonies in dilution 10-1 is the most in dangke 1, dangke 2, and dangke 5, dilution 10-2 is the most in dangke 1, dilution 10-3 is the most in dangke 2, dilution 10-4 is the most in dangke 3, dilution 10-5 is the most in dangke 3. Percentage concentration of dangke 1 (33.3%), dangke 2 (25%), dangke 3 (20%), dangke 4 (20%), dangke 5 (25%). Morphology of bacilli bacteria with gram-positive bacteria type. Buffalo milk dangke contains probiotic bacteria Genus Lactobacillus beneficial for health that can help the digestive process, increase immunity, and can produce bacteriocins to fight pathogenic bacteria. Conclusion: There is a morphology of bacillus bacteria with streptobacillus colonies including gram-positive bacteria in traditional buffalo milk dangke food, which is classified as probiotic bacteria of the Lactobacillus genus.

Comparison of Antioxidants in Red Ginger Powder Preparations with the Addition of Sucrose and Red Ginger Powder Preparations Without the Addition of Sucrose Kamaluddin, Irna Diyana Kartika; Nawawi, Nurafni Maharani; Syamsu, Rachmat Faisal; Royani, Ida; Bima, Irmayanti Haidir
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3554

Antioxidants are compounds that can inhibit oxidation reactions in the human body. Antioxidants can be obtained from food intake. Intake containing antioxidant compounds can also be found in red ginger. Red ginger is available in the form of instant powder obtained through a crystallization process using sucrose as the main agent. Granulated sugar has a sucrose content of 99.95% and functions as a sweetener as well as a crystallization agent that affects the speed of crystallization. This study aims to determine the comparison of antioxidant levels contained in red ginger powder with the addition of sucrose and without the addition of sucrose. The research design used was experimental research design by testing the comparison of antioxidant compound activity between red ginger powder added sucrose and red ginger powder without added sucrose using DPPH reagent measured by spectrophotometer. The measurement of antioxidant content showed that red ginger powder without added sucrose has a very strong IC50 value of antioxidant activity with a value of 46.12 ppm while red ginger powder without added sucrose has a weak IC50 value of antioxidant activity with a value of 205.47 ppm. The results of antioxidant activity testing on both red ginger powders were then statistically tested using the unpaired T-Test test with a p-value <0.05 which means significant. It can be concluded that there is a significant difference in antioxidant activity values between red ginger powder without added sucrose and red ginger powder with added sucrose.

Pengaruh Anemia dan Preeklampsia terhadap Kejadian Bayi Berat Lahir Rendah (BBLR) Cahyani, Pramesty Regita; Dahliah, Dahliah; Makmun, Armanto; Kamaluddin, Irna Diyana Kartika; Darma, Sidrah
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.131

Anemia and preeclampsia during pregnancy contribute significantly to the risk of low birth weight (LBW) in neonates. Anemia, characterized by hemoglobin levels below 11 g/dL in the first and third trimesters, and below 10 g/dL in the second trimester, and preeclampsia, which involves hypertension and organ dysfunction after 20 weeks of pregnancy, can interfere with the supply of oxygen and nutrients to the fetus, causing LBW. The study conducted a Literature Review of 840 articles, and found that anemia increased the risk of LBW by about 1.49 times, while preeclampsia also had a significant association with LBW. These findings suggest the importance of early detection and treatment of anemia and preeclampsia to improve neonatal health outcomes. Further research is needed to develop more effective interventions to address these conditions.

Literatur Review : Analisis Faktor Pembekuan Darah dan Gambaran Radiologi pada Pasien Covid 19 Basri, Hasri Ainun; Syahril, Erlin; Damopolii, Suciati; Damopolii; Kamaluddin, Irna Diyana Kartika
Innovative: Journal Of Social Science Research Vol. 4 No. 5 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i5.14944

COVID-19 is a contagious illness caused by a newly identified coronavirus, Sars-Cov 2 (Severe Acute Respiratory Syndrome Coronavirus 2), which was identified in 2019. Thrombocytopenia, increased D-dimer, delayed prothrombin time, and disseminated intravascular coagulation were among the abnormalities of blood clotting factors seen in COVID-19 patients. Increased D-dimer concentrations, slightly reduced platelet counts, and delayed prothrombin time are typical findings in individuals with coagulopathy who are infected with COVID-19. To confirm a diagnosis of COVID-19 in individuals infected with SARS-CoV-2, radiographic tests such CT scans and thoracic photographs are required. Radiological examinations and CT-Scan and thoracic photo which is often found ground glass opacities, crazy-paving, pleural effusion, sub-pleural bands, pulmonary edema, consolidation, reticular opacities and paracardiac atelectasis, traction bronchiectasis and vacuolar signs. This study aims to analyse blood coagulation factors and radiological features in covid 19 patients. A Literature Review with a Narrative Review is the methodology used in this research. Secondary data sourced from electronic sites such as Pubmed, Clinical Key, and Springer Link provide the bulk of this study's data set. Articles were found using the following keywords: COVID-19, radiological imaging, blood clotting factors. In order to address the research issue statement, 20 research papers were chosen from the scope literature. Radiological imaging and blood clotting factors in COVID-19 patients were reported in 20 separate investigations. The review's findings suggest that radiographic exams for coagulation abnormalities and ground glass opacities are common in individuals with severe COVID-19 infection.

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