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Hubungan Dislipidemia Terhadap Terjadinya Keluhan Neuropati Diabetik pada Pasien Diabetes mellitus di Rumah Sakit Ibnu Sina Makassar Tahun 2023: The Relationship between Dyslipidemia and the Occurrence of Diabetic Neuropathy Complaints in Diabetes mellitus Patients at Ibnu Sina Hospital Makassar Year 2023 Taufiqurrahman, Muhammad; Hidayati, Prema Hapsari; Mulyadi, Farah Ekawati; Kanang, Indah Lestari Daeng; Nur, M. Jabal
Journal of Aafiyah Health Research (JAHR) Vol. 5 No. 2 (2024): JULY-DECEMBER
Publisher : Postgraduate Program in Public Health, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52103/jahr.v5i2.1835

Abstract

ABSTRAK Latar Belakang: Diabetes mellitus adalah gangguan/penyakit metabolik yang ditandai dengan kadar glukosa darah tinggi (hiperglikemia) akibat gangguan pada kerja insulin, sekresi insulin atau keduanya. Pada pasien diabetes mellitus resiko kelainan lipid plasma jauh lebih tinggi. Dislipidemia didefinisikan sebagai kelainan metabolisme lipid yang ditandai dengan penurunan atau peningkatan kadar fraksi lipid dalam plasma. Neuropati diabetik adalah salah satu komplikasi yang sangat sering terjadi pada penderita diabetes mellitus. Tujuan: Untuk Mengetahui hubungan dislipidemia terhadap terjadiya keluhan neuropati diabetik pada pasien diabetes mellitus. Metode: Penelitian ini merupakan studi analitik observasional dengan pendekatan cross sectional menggunakan data rekam medis pasien di rs ibnu sina tahun 2023 sampai 2024. Hasil: Dari total 58 sampel penelitian didapatkan hasil bahwa sebanyak 70,5 % pasien diabetes mellitus mengalami dislipidemia dan 56,9 % penderita diabetes mellitus dengan dislipidemia mengalami keluhan neuropati diabetik. Dislipidemia memiliki hubungan yang signifikan (nilai p 0,006) dengan kejadian keluhan neuropati diabetik pada pasien diabetes mellitus. Kesimpulan: Terdapat hubungan dislipidemia dengan kejadian neuropati diabetik pada pasien diabetes mellitus di Rumah Sakit Ibnu Sina Makassar. ABSTRACT Background: Diabetes mellitus is a metabolic disorder/disease characterized by high blood glucose levels (hyperglycemia) due to disturbances in insulin work, insulin secretion or both. In diabetes mellitus patients, the risk of plasma lipid abnormalities is much higher. Dyslipidemia is defined as a lipid metabolism disorder characterized by decreased or increased levels of lipid fractions in plasma. Diabetic neuropathy is a complication that often occurs in diabetes mellitus sufferers. In Indonesia, 60% of diabetic neuropathy complications occur in diabetes mellitus. Objective: To determine the relationship between dyslipidemia and the occurrence of diabetic neuropathy complaints in diabetes mellitus patients. Method: This research is an observational analytical study with a cross sectional approach using patient medical record data at Ibnu Sina Hospital from 2023 to 2024. Results: From a total of 58 research samples, the results showed that 70.5% of diabetes mellitus patients experienced dyslipidemia and 56.9% of diabetes mellitus patients with dyslipidemia experienced complaints of diabetic neuropathy. Dyslipidemia has a significant relationship (p value 0.006) with the incidence of diabetic neuropathy complaints in diabetes mellitus patients. Conclusion: There is a relationship between dyslipidemia and the incidence of diabetic neuropathy in diabetes mellitus patients at Ibnu Sina Hospital Makassar.
Efikasi Herba Timi (Thymus Vulgaris L.) Sebagai Antibiotik Terhadap Klebsiella Pneumoniae Nasrun, Muhammad Fikri; Wiriansya , Edward Pandu; Musa, Inna Mutmainnah; Kanang, Indah Lestari Daeng; Muchtar, Amrizal
Innovative: Journal Of Social Science Research Vol. 3 No. 6 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i6.8338

Abstract

Thymus vulgaris dianggap sebagai antiseptik, antimikroba, disenfektan dan obat-obatan bersifat tonik. Thymus vulgaris L. dapat digunakan sebagai bahan makanan dan bahan pengobatan karena komposisinya dengan turunan monoterpen termasuk p-cymene, thymol dan carvacrol. T. vulgaris L. memiliki sifat hepatoprotektif serta memiliki efektivitas sebagai agen ekspektoran, agen anti-jerawat, dan menjadi obat fungisida serta antivirus. Tujuan dari penelitian ini adalah untuk menilai kemampuan Thymus vulgaris L. sebagai antiobiotik terhadap Klebsiella pneumoniae dengan mengambil serbuk dari daun tanaman ini. Penelitian yang digunakan adalah penelitian experimental post test dengan menggunakan metode disc diffusion (metode Kirby Bauer) untuk melihat efektivitas dari ekstrak Herba timi (Thymus vulgaris) pada pertumbuhan bakteri Klebsiella pneumoniae. Hasil penelitian menunjukkan bahwa ekstrak daun Herba timi (Thymus vulgaris L.) tidak memiliki aktivitas sebagai antibakteri sehingga tidak dilakukan pengukuran zona hambat pertumbuhan bakteri dan mengkategorikan daya hambat bakteri Klebsiella pneumoniae, walaupun terdapat senyawa kimia aktif dalam daun Herba timi (Thymus vulgaris L.) yaitu alkaloid, saponin, flavonoid, terpenoid, steroid dan tanin.
FAKTOR RISIKO YANG MEMENGARUHI KEJADIAN HIV (Human Immunodeficiency Virus) PADA LAKI-LAKI DI RSUP DR. WAHIDIN SUDIROHUSODO MAKASSAR TAHUN 2020-2021 Mokhtar, Shulhana; Wahid, Syarifuddin; Kanang, Indah Lestari Daeng; Iskandar, Darariani; Yuniarizka, Sekila
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 7 No. 3 (2023): DESEMBER 2023
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v7i3.22245

Abstract

Penyakit Human Immunodeficiency Virus (HIV) menyebabkan penurunan sistem kekebalan tubuh dan dapat berakibat fatal. Pada tahun 2017, terdapat 35 juta penderita HIV dengan 940.000 jiwa meninggal dunia. Kasus HIV telah mencapai 50.282 pada tahun 2019. Faktor risiko meliputi perilaku seksual berisiko, penggunaan jarum suntik terkontaminasi, dan tingkat pendidikan rendah. Oleh karena banyaknya faktor risiko HIV, peneliti tertarik untuk meneliti faktor risiko yang memengaruhi kejadian HIV pada laki-laki di RSUP Dr. Wahidin Sudirohusodo Makassar Tahun 2020-2021. Tujuan penelitian adalah mengetahui faktor risiko kejadian pada laki-laki di RSUP Dr. Wahidin Sudirohusodo Makassar tahun 2020-2021. Metode penelitian yaitu deskriptif dilakukan pendekatan retrospektif. Penelitian ini dilakukan pada bulan September sampai dengan November Tahun 2023 di RSUP Dr. Wahidin Sudirohusodo Makassar. Sampel merupakan pasien laki-laki yang terdiagnosa HIV di RSUP Dr. Wahidin Sudirohusodo Makassar Tahun 2020-2021. Variabel dalam penelitian ini adalah faktor-faktor risiko HIV dan angka kejadian HIV pada laki-laki. Pengumpulan data diperoleh dari data sekunder yaitu rekam medik. Analisis data menggunakan uji univariat. Hasil penelitian diperoleh 39 pasien laki-laki yang menderita HIV dengan faktor risiko utama yaitu penggunaan jarum tidak steril (33,3%), homoseksual (51,3%), heteroseksual (berganti-ganti pasangan) (41%), tingkat pendidikan rendah (66,7%), serta kombinasi faktor risiko yang paling memengaruhi kejadian HIV yaitu kombinasi homoseksual dan tingkat pendidikan rendah (28,20%). Faktor risiko utama yang memengaruhi kejadian HIV pada laki-laki adalah homoseksual dan tingkat pendidikan yang rendah.  
The Effect of Mango Leaf Extract Administration on Fasting Blood Sugar Levels in Deksametason-Induced Mice Tola, Aqilah Faizah; Wahid, Syarifuddin; Kanang, Indah Lestari Daeng; Hidayati, Prema Hapsari; Dirgahayu L, Andi Millaty
Jurnal Kesehatan Vol 18, No 2 (2025): Jurnal Kesehatan
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jk.v18i2.7244

Abstract

Latar Belakang: Daun mangga memiliki efek anti-diabetes karena kandungan mangiferin yang tinggi. Mangiferin memberikan efek anti-diabetes dengan meningkatkan ekspresi GLUT4 dan translokasinya di dalam sel otot. Tujuannya adalah untuk mengetahui pengaruh ekstrak daun mangga (Mangifera foetida) terhadap kadar gula darah puasa pada mencit yang sebelumnya diinduksi deksametason untuk meningkatkan kadar gula darah puasa. Metode: Penelitian eksperimental dengan rancangan pre-test dan post-test group control design. Besar sampel ditentukan menggunakan pendekatan resource equation, dengan total 25 ekor mencit yang dibagi menjadi lima kelompok. Hiperglikemia diinduksi menggunakan deksametason dosis 1 mg/kgBB per hari selama 7 hari, kemudian dilanjutkan dengan pemberian ekstrak daun mangga per oral (dosis 150, 250, dan 350 mg/kgBB per hari) selama 10 hari. Kadar gula darah puasa diukur sebelum dan sesudah induksi, serta pada hari ke-3, ke-7, dan ke-10 setelah pemberian perlakuan. Analisis statistik dilakukan menggunakan metode multivariat. Data dianalisis dengan ANOVA, Post Hoc LSD, dan Paired Sample T-Test. Hasil: Terdapat penurunan signifikan kadar gula darah puasa pada mencit sebelum dan sesudah pemberian ekstrak daun mangga pada kelompok 2 (ekstrak daun mangga 150 mg/kgBB) dengan p = 0,002, kelompok 4 (deksametason 1 mg/kgBB + ekstrak daun mangga 250 mg/kgBB) dengan p = 0,001, dan kelompok 5 (deksametason 1 mg/kgBB + ekstrak daun mangga 350 mg/kgBB) dengan p < 0,001. Kesimpulan: Ekstrak daun mangga (Mangifera foetida) dapat menurunkan kadar gula darah puasa pada mencit yang telah diinduksi.   Background: Mango leaves have anti-diabetic effects due to their high content of mangiferin. Mangiferin exerts its anti-diabetic effects by increasing the expression of GLUT4 and its translocation within muscle cells. The aim is to determine the effect of mango leaf extract (Mangifera foetida) on fasting blood glucose levels in mice previously induced with dexamethasone to elevate fasting blood glucose levels. Method: An experimental method with a pre-test and post-test group control design. The sample size was determined using the resource equation approach, with a total of 25 mice divided into five groups. Hyperglycemia was induced with dexamethasone at 1 mg/kg body weight per day for 7 days, followed by oral administration of mango leaf extract (150, 250, 350 mg/kg body weight per day) for 10 days. Fasting blood glucose levels were measured before and after induction, as well as on days 3, 7, and 10 of treatment. Statistical analysis was performed using multivariate methods. Data were analyzed using ANOVA, Post Hoc LSD, and Paired Sample T-Test. Results: There was a significant decrease in fasting blood glucose levels in mice before and after administration of mango leaf extract in group 2 (Mango leaf extract 150 mg/kg BW) with a p-value of 0.002, group 4 (Dexamethasone 1 mg/kg BW + Mango leaf extract 250 mg/kg BW) with a p-value of 0.001, and group 5 (Dexamethasone 1 mg/kg BW + Mango leaf extract 350 mg/kg BW) with a p-value of <0.001. Conclusion: Mango leaf extract (Mangifera foetida) can reduce fasting blood sugar levels in mice that have been induced.
The Relationship Between White Blood Cell Count and Fever Duration in Typhoid Fever Patients at Ibn Sina Hospital, Makassar City, in 2023 Zulhijjah, A. Nurul Aimmah; Hadi, Santriani; Safei, Imran; Julyani, Sri; Kanang, Indah Lestari Daeng
Jurnal Kesehatan Vol 18, No 2 (2025): Jurnal Kesehatan
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jk.v18i2.8287

Abstract

Pendahuluan: Demam tifoid merupakan penyakit infeksi sistemik yang disebabkan oleh Salmonella Typhi, di mana endotoksin yang dihasilkan oleh bakteri tersebut dapat memengaruhi jumlah leukosit dan durasi demam. Penelitian ini bertujuan untuk mengetahui hubungan jumlah leukosit dengan durasi demam pada pasien demam tifoid di Rumah Sakit Umum Ibnu Sina, Makassar, tahun 2023. Metode: Penelitian ini merupakan penelitian observasional analitik dengan rancangan potong lintang dan pendekatan retrospektif. Data diperoleh dari 506 rekam medis pasien demam tifoid dengan menggunakan teknik total sampling. Analisis data menggunakan uji Chi-Square dengan uji Fisher Exact sebagai alternatif dan uji Spearman Rho. Hasil: Hasil penelitian menunjukkan bahwa mayoritas subjek berjenis kelamin perempuan (54,9%) dengan kelompok usia terbanyak adalah 11–20 tahun (32%). Sebagian besar memiliki jumlah leukosit normal (62,3%) dan mengalami demam akut (86%). Uji Spearman Rho menunjukkan hubungan yang signifikan secara statistik antara jumlah leukosit dan durasi demam (p= 0,049) dengan kekuatan korelasi negatif yang sangat lemah (r = -0,098). Kesimpulan: Dengan demikian, dapat disimpulkan bahwa terdapat hubungan yang signifikan secara statistik antara jumlah leukosit dan durasi demam pada pasien demam tifoid di Rumah Sakit Umum Ibnu Sina Kota Makassar tahun 2023, dengan korelasi terbalik yang sangat lemah.     Introduction: Typhoid fever is a systemic infectious disease caused by Salmonella Typhi, where the endotoxin produced by the bacteria can affect leukocyte counts and fever duration. This study aimed to determine the relationship between leukocyte counts and fever duration in typhoid fever patients at Ibnu Sina General Hospital, Makassar, in 2023. Method: This study is an analytical observational study with a cross-sectional design and a retrospective approach. Data were obtained from 506 medical records of typhoid fever patients using total sampling technique. Data analysis used the Chi-Square test with the Fisher Exact test as an alternative and the Spearman Rho test. Results: The results showed that the majority of subjects were female (54.9%) with the most common age group being 11–20 years (32%). Most had normal leukocyte counts (62.3%) and experienced acute fever (86%). The Spearman Rho test indicated a statistically significant relationship between leukocyte count and fever duration (p= 0.049) with a very weak negative correlation strength (r = -0.098). Conclusion: Therefore, it can be concluded that there is a statistically significant relationship between leukocyte count and fever duration in typhoid fever patients at Ibnu Sina General Hospital in Makassar City in 2023, with a very weak inverse correlation.
Risk Factors for the Incidence of Cholelithiasis at Ibnu Sina Makassar Hospital for the 2021-2023 Period Yusuf, Awalia Rezeki S; Bamahry, Aryanti R; Yanti, Andi Kartini Eka; Gani, Aziz Beru; Kanang, Indah Lestari Daeng
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1721

Abstract

Background: Cholelithiasis is an important health problem with severity and septic complications related to the type of gallstone. Several risk factors also influence the incidence of cholelithiasis. Objective: This study aims to determine the distribution of cholelithiasis patients based on gender, Body Mass Index (BMI), age, childbearing age in women, triglyceride levels, and total cholesterol levels at Ibnu Sina Hospital Makassar in the period 2021 to 2023. Method: This type of research is descriptive using a Cross Sectional Study approach, namely explaining the risk factors for the incidence of cholelithiasis at Ibnu Sina Hospital Makassar. Results: The distribution of cholelithiasis patients at Ibnu Sina Hospital Makassar in 2021-2023 shows that the risk factors are mostly female, overweight/obesity, age >40 years, hypertriglyceridemia, and hypercholesterolemia. However, women of childbearing age suffer less from cholelithiasis than older women. Conclusion: Cholelithiasis at Ibnu Sina Hospital Makassar in 2021-2023 is more common in women, >40 years of age, overweight/obesity, hypertriglyceridemia, and hypercholesterolemia, with a lower incidence in women of childbearing age compared to old age.
PERAN POLA MAKAN DAN AKTIVITAS FISIK DALAM PENGENDALIAN DIABETES MELITUS TIPE 2 DI PUSKESMAS BARA BARAYA MAKASSAR Subhan, Waode Aqilla Putri Pratama; Harahap, Muhammad Wirawan; Masdipa, Andi; Kanang, Indah Lestari Daeng; Karim, Abdul Mubdi Ardiansar Arifuddin
Jurnal Kedokteran Mulawarman Vol 12, No 2 (2025): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v12i2.20091

Abstract

Diabetes mellitus tipe 2 (DM Tipe 2) semakin meningkat secara global, termasuk di Indonesia. Pola makan dan aktivitas fisik yang buruk berperan dalam pengembangan dan pengelolaan DM Tipe 2. Penelitian ini bertujuan untuk mengetahui hubungan antara pola makan dan aktivitas fisik dalam pengendalian DM Tipe 2 di Puskesmas Bara Baraya Makassar. Metode penelitian ini menggunakan teknik observasional dengan desain cross-sectional dilakukan pada 36 pasien diabetes tipe 2. Data dikumpulkan melalui kuesioner pola makan (FFQ), aktivitas fisik (IPAQ), dan pengukuran kadar glukosa darah puasa serta HbA1c. Analisis bivariat dilakukan dengan uji Chi-square menggunakan SPSS. Hasil analisis menunjukkan hubungan signifikan antara pola makan dengan indeks glikemik sedang dan tinggi terhadap kadar gula darah puasa dan HbA1c (p-value
The Effect of Nutritional Status and Diet on Hipertension Disesase in Tabaringan Health Care Murfat, Zulfitriani; Wahyuni, Arifah Ayu Tri; Bamahry R., Aryanti; Kanang, Indah Lestari Daeng
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6674

Abstract

Hypertension is a disease that is defined as a persistent increase in blood pressure. According to WHO, the increase in hypertension is mainly driven by several factors the main risks are unhealthy eating and living patterns, lack of physical activity, etc. For example, the diet that is thought to be the main cause contains high energy, high carbohydrates, high fat, high cholesterol, high sugar, high salt, instant food and smoking habits. This can also cause fat accumulation which over time will result in weight gain and manifest in hypertension. To determine the effect of nutritional status and diet on the incidence of hypertension at the Tabaringan Community Health Center In this research, the case control method was used with the type of analytical observational research. Data collection techniques use primary data. The collected data was analyzed using the Chi-Square Test. Respondents were taken using techniques consecutive sampling. Respondents were 64 people consisting of 32 people each with hypertension and non-hypertension groups. The results of the study showed that there was a significant relationship between nutritional status and hypertension p=0.000, animal protein diet to hypertension p=0.000, vegetable protein diet to hypertension p=0.000, vegetables diet to hypertension p=0.000, fruits diet on hypertension p=0.000. However, there was no significant relationship between carbohydrate diet and hypertension, p=0.217. There is a significant relationship between overweight/obesity nutritional status and a diet of animal protein, vegetable protein, fruits and vegetables on the incidence of hypertension at the Tabaringan Community Health Center, Makassar City.
Characteristics of Hypertension Patients with Chonic Kidney Disease at Ibnu Sina Hospital, Makassar City Year 2022-2023 Aulia, Nabila; Kanang, Indah Lestari Daeng; Fattah, Nurfachanti; Hamsah, Pratiwi Nasir; Hasbi, Berry Erida
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6676

Abstract

Hypertension is a condition where the systole is more than or equal to 140  and the diastole is more than or equal to 90 mmHg. In Indonesia the number of hypertension sufferers reaches 70 million people. The prevalence of hypertension in adults is 6-15%. Hypertension that has been going on for a long time and is not controlled, impacts the blood vessels in the kidneys and causes sclerosis of the blood vessels resulting in glomerular damage and tubular atrophy leading to kidney damage. methods: This is a descriptive study with a cross design sectional Results : Hypertension sufferers with the highest incidence of chronic kidney disease are aged 55-64 years (32.9%), the gender is mostly male (57.6%) while female (424%), with a long history of suffering from hypertension is ≥5 year (63,5%), the highest blood pressure control was found in uncontrolled blood pressure (56.5%), and the use of antihypertensive drugs in the form of CCB drugs (51.8%).Conclusion: Hypertensive patients with the incidence of chronic kidney disease at Ibnu Sina Hospital, Makassar City in 2022-23 are mostly at the age of 55-64 years, male with a long history of suffering from hypertension of 5-10 years and control of uncontrolled blood pressure and use of other types of antihypertensive medication, namely Calcium Channel Blocker (CCB).
The Effect of Honey on Lowering Blood Pressure in Hypertension Elderly at Werdha Theodora Nursing Home, Makassar Ngutro, Rania Hairunnisa; Mokhtar, Shulhana; Khalid, Nur Fadhillah; Royani, Ida; Kanang, Indah Lestari Daeng
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.6713

Abstract

Hypertension is a risk factor that contributes to the development of stroke, heart failure, myocardial infarction and kidney failure. Even though in some cases the symptoms can be found, there are quite a few who think of it as just an ordinary disorder so they realize too late that hypertension is affected. This study aims to determine the effectiveness of giving honey in reducing blood pressure in elderly people with hypertension at the Theodora Makassar Nursing Home. This type of research is experimental with a cross-sectional design. The sampling technique was purposive sampling for 7 research subjects. Data was collected through primary data measuring blood pressure before and after administering forest honey with and/or without antihypertensive medication. The statistical test used is the paired T test. The results showed that the average systolic blood pressure before giving honey was 143.28 mmHg and after giving honey 134.14 mmHg. Then the diastolic blood pressure before honey was 82.14 mmHg and after honey 71.85 mmHg. The average systolic and diastolic blood pressure after administering honey was 134.14 mmHg and 71.85 mmHg. The statistical test results obtained a p-value of 0.018 for systolic blood pressure and a p-value of 0.011 for diastolic blood pressure (p<0.05). The conclusion is that giving honey is effective in reducing blood pressure in elderly people suffering from hypertension at the Theodora Makassar Nursing Home.