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All Journal Jurnal Kedokteran Meditek Holistik Jurnal Kesehatan
Langi, Fima Lanra Fredrik Gerarld
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Faktor- faktor yang Berhubungan dengan Kadar 25 Hidroksi Vitamin D Serum pada Anak dengan Lupus Eritematosus Sistemik wibawa, Valerie viola; Takumansang, Raynald O; Mandei, Jose M; Langi, Fima Lanra Fredrik Gerarld
Jurnal Kedokteran Meditek Vol 31 No 4 (2025): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i4.3708

Abstract

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organ systems. Pediatric-onset SLE (pSLE) often presents with more severe organ involvement and a more aggressive course than adult-onset cases. Vitamin D, known for its immunomodulatory effects, has been implicated in SLE pathogenesis, yet data on serum 25-hydroxy vitamin D [25(OH)D] levels in pediatric patients remain limited. Objective:  This study aimed to assess serum 25(OH)D levels in children with SLE and identify related factors. Methods: A cross-sectional observational study was conducted on 22 pediatric SLE patients aged 5–18 years treated at Prof. Dr. R. D. Kandou General Hospital, Manado. Patients with chronic kidney disease, nephrotic syndrome, chronic liver disease, congenital skeletal disorders, or parathyroid dysfunction were excluded. Serum 25(OH)D levels were measured via ELISA, along with other laboratory parameters. Results: Results showed all patients had vitamin D deficiency, with a mean level of 11.93 ± 5.25 ng/mL. Multivariate regression analysis revealed significant associations between vitamin D levels and complement C3, disease duration, SLEDAI scores, and dsDNA levels.  Conclusion: Vitamin D deficiency is prominent among pSLE patients and is linked to disease activity and severity, suggesting its potential role in disease management and the need for further research
Analisis faktor lama kerja dan kebiasaan merokok terhadap kapasitas vital paru pekerja industri mebel Mingkid, Jessica Gladys; Kalesaran, Angela Fitriani Clementine; Langi, Fima Lanra Fredrik Gerarld
Holistik Jurnal Kesehatan Vol. 19 No. 12 (2026): Volume 19 Nomor 12
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i12.1871

Abstract

Background: The furniture industry is known to pose a high risk for respiratory health problems due to exposure to wood dust and behavioral factors such as smoking. Lung vital capacity may decline with increased exposure to respiratory irritants, and smoking can further impair pulmonary function. This condition is important to examine among furniture workers, who are frequently exposed to long-term occupational hazards. Purpose: To analyze the factors of length of work and smoking habits on the vital lung capacity of furniture industry workers. Method: A descriptive analytic design with a cross-sectional approach. A total of 62 furniture workers were included using total sampling. Lung vital capacity was measured using spirometry. Data on length of employment and smoking habits were collected through structured questionnaires. The chi-square test was used to analyze the relationships between variables. Results: Of the 62 workers, 52 workers (83.9%) had impaired lung vital capacity, while 10 workers (16.1%) had normal lung vital capacity. The analysis showed no significant relationship between length of employment and lung vital capacity (p > 0.05). However, a significant association was found between smoking habits and lung vital capacity (p < 0.05). Conclusion: Most furniture industry workers in Touliang Oki Village experienced impaired lung vital capacity. Length of employment was not associated with lung vital capacity, whereas smoking habits were significantly related to decreased lung vital capacity. Efforts such as controlling risk factors, promoting smoking cessation, and conducting regular pulmonary health monitoring are recommended to protect workers’ health.   Keywords: Furniture Industry Workers; Length of Employment; Lung Vital Capacity; Respiratory Function; Smoking Habits.   Pendahuluan: Industri mebel merupakan salah satu sektor kerja yang memiliki risiko tinggi terhadap gangguan kesehatan pernapasan akibat paparan debu kayu serta faktor perilaku seperti merokok. Kapasitas vital paru dapat menurun seiring meningkatnya paparan iritan pernapasan dan kebiasaan merokok yang memperburuk fungsi paru. Kondisi ini penting untuk dikaji pada pekerja industri mebel yang memiliki paparan kerja jangka panjang. Tujuan: Untuk menganalisis faktor lama kerja dan kebiasaan merokok terhadap kapasitas vital paru pekerja industri mebel. Metode: Penelitian deskriptif analitik dengan pendekatan cross-sectional. Sampel berjumlah 62 pekerja industri mebel yang dipilih secara total sampling. Pengukuran kapasitas vital paru dilakukan menggunakan spirometri. Variabel lama kerja dan kebiasaan merokok dikumpulkan melalui wawancara dengan kuesioner terstruktur. Analisis hubungan dilakukan menggunakan uji statistik chi-square. Hasil: Dari 62 pekerja, sebanyak 52 pekerja (83.9%) mengalami gangguan kapasitas vital paru dan 10 pekerja (16.1%) memiliki kapasitas vital paru normal. Hasil analisis menunjukkan tidak terdapat hubungan antara lama kerja dengan kapasitas vital paru (p > 0.05). Namun, terdapat hubungan signifikan antara kebiasaan merokok dengan kapasitas vital paru (p < 0.05). Simpulan: Kapasitas vital paru pekerja industri mebel sebagian besar berada dalam kategori terganggu. Lama kerja tidak berhubungan dengan kapasitas vital paru, sedangkan kebiasaan merokok terbukti berhubungan dengan penurunan kapasitas vital paru. Upaya pengendalian faktor risiko, edukasi berhenti merokok, dan pemantauan kesehatan paru secara berkala perlu dilakukan untuk melindungi kesehatan pekerja.   Kata Kunci: Kapasitas Vital Paru-paru; Kebiasaan Merokok; Lama Kerja; Pekerja Industri Mebel.
Hubungan antara perilaku sedentari dengan status gizi pada pelajar Therianto, Febrina Melly Chriesanty; Musa, Ester Candrawati; Langi, Fima Lanra Fredrik Gerarld
Holistik Jurnal Kesehatan Vol. 19 No. 12 (2026): Volume 19 Nomor 12
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i12.2052

Abstract

Background: Sedentary behavior, or a lack of movement, can have negative health consequences if allowed to persist over time. One impact of sedentary behavior is nutritional status. Teenagers who are sedentary are also at higher risk of obesity and non-communicable diseases (chronic illnesses). Purpose: To analyze the relationship between sedentary behavior and nutritional status. Method: This quantitative research used a cross-sectional approach. The population studied were students at State Senior High School 2 Tondano in July-September 2025. The sample used was 88 respondents selected through a total sampling technique. The instruments used were the Physical Activity Questionnaire of Adolescents (PAQ-A) questionnaire to observe physical activity and assess sedentary behavior of students in adolescence, and a height and weight measuring instrument to measure nutritional status. Results: The average physical activity questionnaire of adolescents (PAQ-A) score of students was quite low, with results around 1.80 with a standard deviation of 0.40. The average sample student had a body mass index (BMI) in the good category (mean 22.09 ± 5.14 kg/m2). However, 14 (16%) of the sample students were in the obese category (BMI/U Z score above +2 SD). The results of the bivariate analysis obtained a p value of 0.65 (p>0.05), meaning that H0 was accepted and the hypothesis was rejected. This indicates that there is no relationship between sedentary behavior and nutritional status in students. Conclusion: The association between sedentary behavior and nutritional status was not statistically significant, but the direction of the association suggests that lower physical activity may be associated with an increased risk of overnutrition. Suggestion: Further research with longitudinal designs and more objective measures of sedentary behavior is recommended to strengthen the causal evidence.   Keywords: Nutritional Status; Sedentary Behavior; Students.   Pendahuluan: Perilaku sedentari merupakan perilaku menetap atau kurang bergerak, perilaku ini memiliki dampak buruk untuk kesehatan jika dibiarkan dalam waktu yang lama. Salah satu dampak yang dapat dipengaruhi oleh perilaku sedentari yaitu status gizi. Remaja yang kurang bergerak juga dapat berisiko lebih tinggi mengalami kegemukan, hingga berisiko mengalami penyakit tidak menular (penyakit kronis). Tujuan: Untuk menganalisis hubungan antara perilaku sedentari dengan status gizi. Metode: Penelitian kuantitatif dengan pendekatan cross-sectional. Populasi yang diteliti adalah pelajar di SMA Negeri 2 Tondano pada bulan Juli-September 2025. Sampel yang digunakan sebanyak 88 responden yang dipilih melalui teknik total sampling. Instrumen yang digunakan yaitu kuesioner physical activity questionnaire of adolescents (PAQ-A) untuk melihat aktivitas fisik dan menilai perilaku sedentari pelajar diusia remaja, alat ukur tinggi badan dan berat badan untuk mengukur status gizi. Hasil: Rata-rata skor PAQ-A pelajar cukup rendah dengan hasil di sekitar 1.80 dengan standar deviasi 0.40. Rata-rata pelajar sampel memiliki indeks massa tubuh (IMT) dalam kategori baik (mean 22.09 ± 5.14 kg/m2). Namun, sebanyak 14 responden (16%) telah berada di kategori obese (skor Z IMT/U di atas +2 SD). Hasil analisis bivariat diperoleh p value sebesar 0.65 (p>0.05), artinya H0 diterima, maka hipotesis ditolak. Hal ini menunjukkan tidak terdapat hubungan perilaku sedentaridengan status gizi pada pelajar. Simpulan: Hubungan antara perilaku sedentari dan status gizi tidak signifikan secara statistik, namun arah hubungan menunjukkan bahwa aktivitas fisik yang lebih rendah mungkin berkaitan dengan peningkatan risiko gizi lebih. Saran: Penelitian lanjutan dengan desain longitudinal dan pengukuran perilaku sedentari yang lebih objektif disarankan untuk memperkuat bukti kausal.   Kata Kunci: Pelajar; Perilaku Sedentari; Status Gizi.
Co-Authors Kalesaran, Angela Fitriani Clementine Mandei, Jose M Mingkid, Jessica Gladys Musa, Ester Candrawati Takumansang, Raynald O Therianto, Febrina Melly Chriesanty wibawa, Valerie viola