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All Journal Ophthalmologica Indonesiana Cermin Dunia Kedokteran
Gunanegara, Abdi Sastra
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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CORRELATION BETWEEN PLATELET PARAMETERS AND THE SEVERITY OF PRIMARY OPEN ANGLE GLAUCOMA Gunanegara, Abdi Sastra; Yuliawati, Putu; Kusumadjaja, I Made Agus
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/x2jvs545

Abstract

Introduction & ObjectivesPrimary open angle glaucoma (POAG) is a chronic optic neuropathy characterized by slowlyprogressive visual function loss. Platelet activation as well as its interaction with vascularendothelium and plasma components, play an important role in the vascular pathophysiology ofPOAG. Platelet aggregation in glaucoma tends to increase. This change has negative impact on smallvessel circulation in the eye, such as branches of short ciliary arteries supplying the optic nerve. Inthis study, we will assess the correlation between platelet parameters and the severity of POAG. MethodsThis study is an analytical observational study. Data were obtained retrospectively and prospectivelywith a cross sectional study approach conducted at Sanglah Hospital, Denpasar. The study samplewas 62 eyes selected consecutively. Data was analyzed using SPSS. Descriptive data presentednumerically or categorically, bivariate analysis using Pearson and Spearman correlation tests andmultivariate analysis using logistic regression. ResultsResults showed that the mean age of the research subjects was 66.71 ± 9.795 years, with themajority was male (70.6%). Bivariate analysis, showed no significant correlation between plateletparameters (PLT, PDW, MPV) and the severity of POAG. Multivariate analysis found that age ? 68years, 9,850 times more likely to develop moderate to severe glaucoma, compared to patients < 68years old (OR 9,850, 95% CI, p = 0.009). ConclusionPlatelet parameters showed no significant correlation with the severity of POAG, meanwhile olderage is more at risk of developing moderate to severe POAG.
Komplikasi Endoftalmitis Pasca-operasi Katarak Elvira; Gunanegara, Abdi Sastra
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.793

Abstract

The most common intraocular surgery is cataract surgery. Endophthalmitis is a rare complication of intraocular surgery, but very threatening to sight. Intravitreal injection and vitrectomy pars plana are recommended especially in patients with poor visual acuity. Early follow up and appropriate therapies are very important. Late management can change the prognosis of eyesight.
Sindrom Marcus Gunn Kongenital Mengedipkan Rahang: Tinjauan Pustaka Elvira; Gunanegara, Abdi Sastra
Cermin Dunia Kedokteran Vol 51 No 12 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i12.846

Abstract

Marcus-Gunn Jaw-winking syndrome is a rare congenital or acquired condition. This condition is characterized by upper eye lid elevation while opening or moving the jaw. In addition, it is accompanied by ptosis in the affected eye. Treatment options range from observation to surgery. Observation should be routinely done to evaluate any worsening symptoms. Surgery was performed for ocular misalignment and moderatesevere ptosis affecting visual function.
Co-Authors Elvira Kusumadjaja, I Made Agus Yuliawati, Putu