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KARAKTERISTIK PASIEN TUMOR SINONASAL DENGAN PERLUASAN ORBITA DI RSUP PROF NGOERAH PERIODE JANUARI – MEI 2022 Yuliawati, Putu; mahadewi, wistya eka; Utari, made laksmi
E-Jurnal Medika Udayana Vol 13 No 9 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i09.P08

Tumor sinonasal merupakan tumor yang berlokasi kavum nasi dan sinus paranasal yang dekat dengan struktur neurovaskular. Tumor sinonasal memiliki kemungkinan perluasan dan invasi yang tinggi, salah satunya ke orbita. Struktur anatomi yang sulit dan gejala klinis yang tidak khas membuat diagnosis tumor sinonasal seringkali terlambat. Pemahaman lebih dalam mengenai penyakit ini diperlukan. Studi deskriptif dengan pendeketan retrospektif ini dilakukan pada pasien tumor sinonasal dengan perluasan ke mata yang berkunjung ke Poliklinik Mata RSUP Prof Ngoerah Denpasar pada Januari 2020 – Desember 2021. Data penelitian yang dikumpulkan meliputi usia, jenis kelamin, gejala klinis seperti proptosis dan gerak bola mata, lateralisasi, derajat invasi orbita, tipe histologi, dan terapi yang didapatkan. Data kemudian dianalisis secara bivariat. Total sebanyak 22 pasien diinklusi dalam penelitian ini. Tumor sinonasal jinak dilaporkan sebanyak 4 (18,2%) pasien dan sisanya 18 (81,8%) pasien adalah tumor ganas. Rerata usia subyek adalah 58,05 (±12,5) tahun, sebagian besar dalam rentang usia 51-60 tahun (36,4%) dan laki-laki (59,1%). Rerata usia secara signifikan lebih tinggi pada pasien dengan tumor ganas (61,22 vs 43,75 tahun; p=0,008). Sebanyak 86,4% pasien mengalami proptosis dan 18,2% pasien mengalami perluasan mata unilateral. Derajat perluasan orbita terbanyak adalah grade 3 (50%). Masing-masing dua (9,1%) pasien tumor jinak menunjukkan inflamasi kronik dan kista jinak. Pada tipe tumor ganas, mayoritas memiliki tipe adenokarsinoma (27,3%). Tidak terdapat hubungan yang signifikan antara variabel jenis kelamin, lateralisasi, derajat perluasan, dan terapi dengan tipe histologi tumor (p>0,05). Penelitian ini menunjukkan bahwa subyek tumor ganas sinonasal berusia lebih tua dibandingkan dengan tumor jinak sinonasal.

Congenital Orbital Teratoma of the Newborn: A Rare Case Report Yuliawati, Putu; Wetarini, Krisnhaliani; Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Utari, Ni Made Laksmi; Sunariasih, Ni Nyoman
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.19

Congenital orbital teratoma is a rare and complex congenital anomaly due to abnormal tissue growth within the orbit. This case report aims to highlight the significance of early prenatal screening in identifying congenital orbital teratoma and its potential complications. A 6-day-old male newborn presented with macrocephaly and a unilateral massive protrusion of the left eye. Prenatal ultrasonography performed at 36 weeks gestation showed a suspicion of fetal craniofacial mass. Further brain CT scan revealed an orbital heterogeneous mass, with calcified components dominantly in the anterior and middle cranial fossa into the left orbit, which was subsequently diagnosed as congenital orbital teratoma associated with non-communicating hydrocephalus. This finding prompted an urgent ventriculoperitoneal (VP) shunt. Unfortunately, despite prompt intervention, the patient passed away after the procedure. Pathological examination was compatible with an immature teratoma. Multidisciplinary management is warranted to improve diagnostic screening and refine management strategies for better outcomes in such cases.

CHARACTERISTICS TRAUMATIC OPTIC NEUROPATHY PATIENTS AT RSUP PROF. DR. I.G.N.G. NGOERAH DENPASAR YEAR 2022 - 2023 Priwinandari, Ni Made; Triningrat, Anak Agung Mas Putrawati; Yuliawati, Putu; Utari, Ni Made Laksmi
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.40649

Traumatic optic neuropathy (TON) adalah kondisi langka yang dapat mengancam fungsi penglihatan hingga menyebabkan kebutaan. sering kali akibat cedera pada mata atau kepala. Kondisi ini berhubungan erat dengan cedera kraniofasial yang dapat merusak saraf optik secara langsung maupun tidak langsung. Penanganan TON masih kontroversial dan memerlukan pemahaman lebih lanjut mengenai karakteristik pasien untuk mengoptimalkan perawatan dan pengobatan. Penelitian ini bertujuan untuk mengetahui karakteristik pasien dengan traumatic optic neuropathy di RSUP Prof. Dr. I.G.N.G. Ngoerah Denpasar selama tahun 2022-2023. dengan fokus pada faktor-faktor seperti jenis kelamin. usia. domisili. visus awal dan akhir. jenis cedera. jenis trauma. mekanisme trauma. dan tatalaksana. Penelitian ini menggunakan desain studi potong lintang (cross-sectional). Data dikumpulkan dari rekam medis pasien yang memenuhi kriteria inklusi di RSUP Prof. Dr. I.G.N.G. Ngoerah Denpasar pada periode 2022-2023. Pengolahan data dilakukan secara deskriptif dengan total sampling untuk memperoleh gambaran yang representatif. Mayoritas pasien adalah laki-laki (94.7%) dengan rentang usia terbanyak 19-59 tahun (73.7%). Sebagian besar pasien berasal dari daerah Tabanan (31.6%). Visus awal dan akhir pasien lebih banyak terdeteksi pada rentang 6/60 hingga 1/60 (31.6%). Cedera kepala disertai trauma maksilofasial dan fraktur dasar tengkorak merupakan jenis cedera yang paling umum. dengan kecelakaan lalu lintas sebagai mekanisme trauma utama (68.4%). Penggunaan steroid menjadi tatalaksana yang paling umum (47.4%). Traumatic optic neuropathy lebih sering terjadi pada laki-laki dengan usia produktif dan sering kali disebabkan oleh kecelakaan lalu lintas. Penurunan visus yang signifikan terjadi pada sebagian besar pasien. dan tatalaksana menggunakan steroid masih menjadi pilihan utama meskipun pengobatan lebih lanjut masih membutuhkan penelitian lebih mendalam.

Differences of Retinal Nerve Fiber Layer and Ganglion Cell Layer-Inner Plexiform Layer Thickness in Patients without Diabetes Mellitus, with Diabetes Mellitus Type 2 without Diabetic Retinopathy and with Diabetic Retinopathy Sukmawati, Nurindah; Suryathi, Ni Made Ari; Andayani, Ari; Pantjawati, Ni Luh Diah; Widiana, I Gde Raka; Yuliawati, Putu; Juliari, IGAM
International Journal of Retina Vol 8 No 1 (2025): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2025.vol008.iss001.314

Introduction : Prevention of Diabetic Retinopathy (DR) require an examination method that can identify earliest damage before clinical symptoms observed. This study aimed to determine the novel and objective way to detect those damage through RNFL and GCL-IPL thickness. Method : This analytical cross sectional study research conducted at the eye polyclinic and the Diabetic Center of IGNG Ngoerah Hospital, Denpasar. This study comparing the difference in thickness of RNFL and GCL-IPL in patients without DM, with Type 2 DM without DR and with DR in average and each quadrant thickness through Kruskal Wallis and One Way Anova test. Result : The sample was 59 people which then divided into three groups, namely 20 samples in the group without DM, 19 samples in the DM group without DR and 20 samples with DR. The samples were then examined for RNFL and GCL-IPL and the results were compared between groups. The mean age of the subjects were 58.80±9.65 years old. In the RNFL measurement, it was found that there were differences in values between groups in all quadrants except the temporal quadrant (p=0.518). After covariate analysis by variables of age, HbA1c, blood pressure, visual acuity, IOP and axial length, the results change with the nasal and inferior quadrants as the only found significant. In the GCL-IPL analysis there were significant differences between groups, especially in the superotemporal, temporal and inferotemporal quadrants (p<0.005). These results remained after being controlled by covariate analysis. Conclusion : This study proved a neurodegeneration process that occured focally in certain areas that can be detected through the RNFL and GCL-IPL measurement modalities. These examinations were expected to be useful in terms of screening both primary and secondary in patients with type 2 DM.

CORRELATION BETWEEN PLATELET PARAMETERS AND THE SEVERITY OF PRIMARY OPEN ANGLE GLAUCOMA Gunanegara, Abdi Sastra; Yuliawati, Putu; Kusumadjaja, I Made Agus
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/x2jvs545

Introduction & ObjectivesPrimary open angle glaucoma (POAG) is a chronic optic neuropathy characterized by slowlyprogressive visual function loss. Platelet activation as well as its interaction with vascularendothelium and plasma components, play an important role in the vascular pathophysiology ofPOAG. Platelet aggregation in glaucoma tends to increase. This change has negative impact on smallvessel circulation in the eye, such as branches of short ciliary arteries supplying the optic nerve. Inthis study, we will assess the correlation between platelet parameters and the severity of POAG. MethodsThis study is an analytical observational study. Data were obtained retrospectively and prospectivelywith a cross sectional study approach conducted at Sanglah Hospital, Denpasar. The study samplewas 62 eyes selected consecutively. Data was analyzed using SPSS. Descriptive data presentednumerically or categorically, bivariate analysis using Pearson and Spearman correlation tests andmultivariate analysis using logistic regression. ResultsResults showed that the mean age of the research subjects was 66.71 ± 9.795 years, with themajority was male (70.6%). Bivariate analysis, showed no significant correlation between plateletparameters (PLT, PDW, MPV) and the severity of POAG. Multivariate analysis found that age ? 68years, 9,850 times more likely to develop moderate to severe glaucoma, compared to patients < 68years old (OR 9,850, 95% CI, p = 0.009). ConclusionPlatelet parameters showed no significant correlation with the severity of POAG, meanwhile olderage is more at risk of developing moderate to severe POAG.

Congenital Orbital Teratoma of the Newborn: A Rare Case Report Yuliawati, Putu; Wetarini, Krisnhaliani; Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Utari, Ni Made Laksmi; Sunariasih, Ni Nyoman
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.19

Congenital orbital teratoma is a rare and complex congenital anomaly due to abnormal tissue growth within the orbit. This case report aims to highlight the significance of early prenatal screening in identifying congenital orbital teratoma and its potential complications. A 6-day-old male newborn presented with macrocephaly and a unilateral massive protrusion of the left eye. Prenatal ultrasonography performed at 36 weeks gestation showed a suspicion of fetal craniofacial mass. Further brain CT scan revealed an orbital heterogeneous mass, with calcified components dominantly in the anterior and middle cranial fossa into the left orbit, which was subsequently diagnosed as congenital orbital teratoma associated with non-communicating hydrocephalus. This finding prompted an urgent ventriculoperitoneal (VP) shunt. Unfortunately, despite prompt intervention, the patient passed away after the procedure. Pathological examination was compatible with an immature teratoma. Multidisciplinary management is warranted to improve diagnostic screening and refine management strategies for better outcomes in such cases.

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