Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Journal of Innovative and Creativity
Heldayani, Debby
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Physics Social Sciences Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Antibacterial Activity Test of Gotu Kola Leaf Extract (Centella asiatica) Against Staphylococcus aureus Bacteria Isolated from Wounds of Diabetes Mellitus Patients Fioni; Heldayani, Debby; Lister, Gilbert; Tambunan, Andika Zayani
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.6046

Abstract

Staphylococcus aureus, a gram-positive bacterium, is the causative agent of diabetic foot. Traditional medicine using plants needs much further research, especially for wound healing in diabetes mellitus patients. This study is an experimental laboratory investigation on the efficacy of Gotu kola (Centella asiatica) leaf extract against wound-isolated Staphylococcus aureus. Gotu kola leaf extract (12.5%, 25%, 50%, 75%, and 100%), cefixime suspension (positive control), and sterile distilled water were tested. The results of the research showed the formation of an inhibitory zone from testing Gotu kola leaf extract against Staphylococcus aureus bacteria, where the average inhibitory zone was at concentrations of 12.5% (7.2 mm), 25% (11 mm), 50% (13.7 mm), 75% (14 .3 mm), and 100% (19.5 mm). The higher the concentration used, the larger the inhibition zone formed. Research shows that Gotu kola leaves' active substances inhibit energy formation, nucleic acid formation, cell membrane permeability, structure and function, and membrane protein lysis and damage.
FORMULASI DAN UJI SUN PROTECTION FACTOR (SPF) SEDIAAN KRIM EKSTRAK ETANOL 96% DAGING BUAH LABU SIAM (Sechium edule (Jacq.) Sw.) SECARA IN VITRO Daskar, Annajim; Heldayani, Debby; Baity, Eva Nurul
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.4026

Abstract

Excessive exposure to ultraviolet (UV) rays can cause various damage to the skin, such as premature aging and skin cancer. The use of natural sunscreens is a safe and environmentally friendly alternative. Chayote (Sechium edule (Jacq.) Sw.) is known to contain active compounds such as flavonoids and phenolics that have the potential as photoprotective agents. This study aims to formulate a cream preparation of 96% ethanol extract of chayote flesh and evaluate its physical characteristics and Sun Protection Factor (SPF) value in vitro. This study used an experimental method. The flesh of chayote (Sechium edule (Jacq.) Sw.) was extracted using the maceration method, followed by the development of a topical cream formula and measurement of the Sun Protection Factor (SPF) value in vitro using. Based on the results of physical characteristic tests, all formulas showed compliance with the criteria for good cream quality, except in the protection power test, where reddish spots were observed in formula F2, and in the physical stability test, emulsion phase separation was found. The SPF value increased with increasing extract concentration. Formula F1 showed an SPF of 15.88; F2 16.68; and F3 18.52, categorized as moderate to high protection. Therefore, chayote pulp extract cream has the potential to be a safe and effective natural sunscreen. It can be concluded that the chayote pulp extract cream preparation has the potential to be used as a natural sunscreen.
Co-Authors Baity, Eva Nurul Daskar, Annajim Fioni Lister, Gilbert Tambunan, Andika Zayani