Article Per Year (5 Year)
p-Index From 2021 - 2026
0.778
P-Index
This Author published in this journals
All Journal International Journal of Health, Engineering and Technology
Anggita Dian Karera
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Inotrope Use and the Risk of Intraventricular Hemorrhage in Preterm Neonates: A Systematic Review and Meta Analysis Anggita Dian Karera; Delta Iswara; Amanah Sekar Kinasih; Dyah Ati Sayuka; Din Alfina
International Journal of Health Engineering and Technology Vol. 4 No. 4 (2025): IJHET NOVEMBER 2025
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

More than 40% of neonatal hypotension cases are managed with inotropes; however, recent evidence indicates that inotrope administration, rather than hypotension itself, is independently associated with an increased risk of intraventricular hemorrhage (IVH) after adjustment for confounding factors. This systematic review and meta-analysis aimed to evaluate the association between inotrope use and the occurrence of IVH among preterm neonates. The study followed PRISMA guidelines. A systematic literature search was conducted through PubMed, Scopus, ScienceDirect, and Google Scholar. The methodological quality of each study was assessed using the Newcastle-Ottawa Scale (NOS) for case-control and cohort designs. Relevant data were extracted for qualitative and quantitative synthesis. Meta-analysis was performed using a random-effects model based on adjusted odds ratios (aORs) reported in each study, and the results were presented as pooled aORs with 95% confidence intervals. Eight studies met the inclusion criteria. The meta-analysis showed that inotrope use was significantly associated with a higher risk of IVH in preterm neonates, including IVH of any grade (pooled OR 2.03, 95% CI 1.25-3.29) and severe IVH (pooled OR 2.00, 95% CI 1.33-3.02). Overall, inotrope use doubled the risk of IVH (pooled OR 2.00, 95% CI 1.48-2.70). These findings emphasize the need for cautious and strictly indicated inotrope administration along with standardized hemodynamic management.
Neonatal Dengue: A Case Series of Three Patients with a Wide Clinical Spectrum Anggita Dian Karera; Hana Amelia; Delta Iswara; Din Alfina
International Journal of Health Engineering and Technology Vol. 4 No. 4 (2025): IJHET NOVEMBER 2025
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Neonatal dengue is an uncommon but clinically important condition that can present with a wide range of symptoms. This report describes three neonatal dengue cases with distinct clinical manifestations and emphasizes the importance of early recognition. The objective of this case series is to outline the clinical features, laboratory findings, and treatment outcomes of the affected neonates. All three patients presented with fever accompanied by various symptoms, including seizures, jaundice, respiratory distress, and significant thrombocytopenia. Diagnostic evaluation consisted of serological testing, hematological assessment, and imaging studies when needed. The lowest platelet counts ranged from 10,000 to 14,000 per microliter, although none of the neonates experienced major bleeding or shock. All patients received supportive treatment, including fluid management, monitoring, and therapy tailored to presenting symptoms. Each neonate demonstrated gradual improvement and was discharged in stable condition following appropriate observation. These cases highlight that neonatal dengue may resemble sepsis and thus requires a high level of diagnostic vigilance, particularly in endemic areas or when maternal dengue is suspected. Early serological testing in both mother and infant is valuable for timely diagnosis. Supportive care and close monitoring contribute significantly to preventing complications and achieving favorable outcomes.
Lung Immune Prognostic Index (Lipi) As Prognostic Markers For Advanced Non-Small-Cell Lung Cancer (Nsclc) Treated With Immunotherapy: A Systematic Review And Meta-Analysis Delta Iswara; Anggita Dian Karera; Dyah Ati Sayuka; Rachmad Aji Saksana
International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v5i1.735

Abstract

The Lung Immune Prognostic Index (LIPI), based on the derived neutrophil-to-lymphocyte ratio (dNLR) and lactate dehydrogenase (LDH) levels, has been recognized as an important prognostic biomarker in lung cancer. However, its prognostic value in patients with non–small cell lung cancer (NSCLC) has not been extensively discussed. Objective: This systematic review and meta-analysis aimed to comprehensively evaluate the association between LIPI and survival outcomes in patients with advanced-stage NSCLC receiving immunotherapy. Systematic literature search was conducted across PubMed, ScienceDirect, Cochrane Library, SSRN, Epistemonikos, and Google Scholar databases up to January 10, 2025. Study quality was assessed using the Newcastle–Ottawa Scale (NOS). Data were extracted for qualitative and quantitative synthesis, including pooled analyses and subgroup analyses. Random-effects models were applied to pool hazard ratios (HRs) with 95% confidence intervals (CIs) to assess the association between LIPI and progression-free survival (PFS) and/or overall survival (OS) in patients with advanced NSCLC treated with immunotherapy. A total of 7,551 patients from 13 studies were included in the analysis. Pooled analysis demonstrated that patients with poor or intermediate LIPI scores, compared with those with good LIPI scores, had significantly shorter PFS (HR = 2.20, 95% CI: 1.83–2.63, P < 0.001; HR = 1.47, 95% CI: 1.31–1.65, P < 0.001) and worse OS (HR = 3.31, 95% CI: 2.70–4.06, P < 0.001; HR = 1.88, 95% CI: 1.58–2.23, P < 0.001). Subgroup analyses based on immunotherapy type (monotherapy versus combination therapy) yielded consistent results. This study demonstrates that poor and intermediate LIPI scores are significantly associated with worse prognosis in patients with advanced-stage NSCLC receiving immunotherapy. Therefore, LIPI may serve as a promising non-invasive prognostic biomarker for predicting survival outcomes in this patient population. Keywords: lung immune prognostic index, LIPI, non–small cell lung cancer, immunotherapy.
Moderate Hyperkalemia Presenting As Sinus Arrest With Junctional Escape Rhythm From A Hospital With Resources Limited Setting: A Case Report And Narrative Review Delta Iswara; Anggita Dian Karera; Satrya Yudha Dwi Putranto; Rois Hasyim
International Journal of Health Engineering and Technology Vol. 5 No. 2 (2026): Vol 5. No. 2 JULY 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v5i2.1073

Abstract

Hyperkalemia is a potentially life-threatening electrolyte disturbance that can cause severe cardiac conduction abnormalities, even at moderate serum potassium levels, particularly in elderly patients with underlying cardiovascular disease. Management of acute hyperkalemia remains challenging, especially in resource-limited healthcare settings where advanced therapies such as urgent dialysis may not be readily available. We report a 77-year-old woman who presented with generalized weakness and recurrent syncope. Electrocardiography revealed sinus arrest with a junctional escape rhythm, and laboratory evaluation showed moderate hyperkalemia (6.84 mmol/L) accompanied by acute kidney injury, anemia, and mild metabolic acidosis. The patient had a history of anterior ST-elevation myocardial infarction and was receiving potassium-retaining medications. She was admitted to the intensive care unit and treated with protocol-based glucose–insulin therapy, intravenous calcium gluconate, adjunctive β-adrenergic agonists, and supportive care, without immediate access to dialysis. Serial ECGs demonstrated recovery of sinus rhythm, and serum potassium levels gradually normalized. This case illustrates that moderate hyperkalemia can precipitate severe bradyarrhythmias such as sinus arrest. Early recognition of ECG changes and prompt, protocol-driven management can result in favorable outcomes, even in resource-limited settings without immediate dialysis availability.
Co-Authors Amanah Sekar Kinasih Delta Iswara Delta Iswara Din Alfina Dyah Ati Sayuka Dyah Ati Sayuka Hana Amelia Rachmad Aji Saksana Rois Hasyim Satrya Yudha Dwi Putranto