Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Journal of General Procedural Dermatology and Venereology Indonesia
Menaldi, Sri Linuwih Susetyo Wardhani
Unknown Affiliation
Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
The spectrum of cutaneous manifestations in COVID-19 patients at Dr. Cipto Mangunkusumo Hospital Widaty, Sandra; Menaldi, Sri Linuwih Susetyo Wardhani; Miranda, Eliza; Marissa, Melani; Nilasari, Hanny; Melinda, Thong Felicia; Cornain, Emilina Faradila
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Cutaneous manifestations are identified in 0.2%–20% of COVID-19 cases, both in adult and pediatric patients. They can occur before, simultaneously with, or after the systemic symptoms of COVID-19. This study aims to analyze the association between cutaneous manifestations, severity, and outcomes of patients with COVID-19. Methods: This observational study was conducted from April 2020 to April 2021 in Dr. Cipto Mangunkusumo Hospital, a referral center for COVID-19 in Jakarta, Indonesia. Medical records were used to collect demographic, clinical, and laboratory data. Results: A total of 0.61% (31/5070) of COVID-19 cases showed cutaneous manifestations, consisting of maculopapular (80.6%), vesicular (16.1%), livedoid (6.4%), pseudo-chilblain (3.2%), and urticarial (3.2%) lesions, with three patients showing more than one cutaneous manifestation. In the present study, only 2,001 out of 5,070 patients were appropriately confirmed to suffer from COVID-19 infection. Multisystem inflammatory syndrome in children (MIS-C) was identified in one out of eleven patients under 21 years old. Laboratory examinations showed an increased neutrophil-to-lymphocyte ratio (NLR), C-reactive protein (CRP), procalcitonin, D-dimer, and creatinine alongside a decreased albumin level. Conclusion: We reported various cutaneous manifestations and diagnostic test results associated with COVID-19. More than one cutaneous manifestations are present in several COVID-19 patients in our study. Several contradictory findings relative to previous publications indicate the necessity of collecting more data regarding the cutaneous manifestation of COVID-19.
Difficulties in diagnosing primary cutaneous mucormycosis: Excluding mycobacterium other than tuberculosis Indah, Chinda Liaska; Menaldi, Sri Linuwih Susetyo Wardhani; Sirait, Sondang Pandjaitan; Widaty, Sandra
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Mucormycosis is a rare fungal infection caused by a group of opportunistic fungi from the class Zygomycetes. Primary cutaneous mucormycosis is the most common type of mucormycosis in immunocompetent patients. This study reported a case of primary cutaneous mucormycosis with nonspecific clinical characteristics and various supporting examinations. The patient was successfully treated with in toto excision and oral ketoconazole. Case Illustration: A 40-year-old female presented with purplish-red spots and painless lumps on the second finger of her right hand, which had been present for a year. She had a history of frequent fish tank cleaning and gardening but denied any known injury. Physical examination revealed multiple well-circumscribed and confluent erythematous-violaceous plaques and nodules. An in toto excisional biopsy was performed for histopathological examination, culture, and a rapid molecular test (RMT) using the Xpert MTB/RIF® test (Cepheid, USA). Histopathological examination revealed granulomatous suppurative inflammation, and fungal culture revealed growth of Mucor species. Discussion: Clinical findings in cutaneous mucormycosis are nonspecific. The diagnosis is confirmed by identifying the organism through biopsy and histopathological examination, as well as culture. Histopathology will reveal granulomas in the dermis and subcutis containing numerous macrophages and Langhans giant cells, often with phagocytosed fungal elements. Fungal culture yields positive results in 72–89% of cases of skin mucormycosis conducted on Sabouraud and potato dextrose agar media. Conclusion: This case emphasizes the need for broad differential consideration and thorough diagnostic workup in nonspecific cutaneous mucormycosis and supports surgical excision with systemic antifungal therapy for chronic, localized primary disease.
Co-Authors Cornain, Emilina Faradila Eliza Miranda Hanny Nilasari Indah, Chinda Liaska Marissa, Melani Melinda, Thong Felicia Sandra Widaty Sirait, Sondang Panjaitan