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Emotional Intelligence and Creative Problem Solving in Business Leaders: A Structural Equation Modeling Approach Prawira, Anggun Wida; Nazarov, Azamat; Khamraev, Javlonbek
Journal of Loomingulisus ja Innovatsioon Vol. 2 No. 4 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/innovatsioon.v2i4.2362

Abstract

Emotional intelligence has increasingly been recognized as a critical factor influencing leadership effectiveness and the capacity for creative problem solving in complex business environments. This study aims to examine the relationship between emotional intelligence and creative problem-solving skills among business leaders by developing and testing a structural equation model. Data were collected from 362 senior managers across diverse industries through standardized instruments measuring emotional intelligence dimensions and creative problem-solving abilities. Structural Equation Modeling (SEM) was applied to analyze direct and indirect relationships between these constructs. The results revealed that emotional intelligence significantly and positively influences creative problem solving, with self-awareness and emotional regulation emerging as the strongest predictors. Indirect effects were also found, indicating that social awareness and relationship management enhance problem-solving outcomes through their influence on decision-making flexibility. The study concludes that leadership development programs emphasizing emotional intelligence can enhance creative capacities, supporting organizational adaptability and long-term competitiveness.
Role of the Gut Microbiome in the Pathogenesis of Crohn’s Disease Demir, Ahmet; Kara, Sevda; Khamraev, Javlonbek
Journal of Biomedical and Techno Nanomaterials Vol. 2 No. 2 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v2i2.2022

Abstract

Crohn's disease is one of the inflammatory bowel diseases (IBD) whose pathogenesis is still not fully understood. Many studies have shown a link between dysbiosis of the gut microbiome and the development of the disease. However, the specific mechanism linking the microbiota to inflammation in Crohn's disease is still open to further exploration. This study aims to investigate the role of the gut microbiome in the pathogenesis of Crohn's disease, specifically in differentiating the composition of the microbiota in patients with active disease and in remission. This study used a cross-sectional design with a sample of 100 patients diagnosed with Crohn's disease. Fecal samples were collected and analyzed using metagenomic techniques (16S rRNA sequencing) to identify the composition of the microbiota. Analysis of inflammatory biomarkers such as C-reactive protein (CRP) is also performed to assess disease status. The results showed that patients with active disease had a decrease in the number of anti-inflammatory bacteria such as Faecalibacterium prausnitzii and an increase in pathogenic bacteria such as Escherichia coli. In addition, there was a correlation between microbiome dysbiosis and increased CRP levels in patients with active disease. Microbiome dysbiosis has an important role in exacerbating the symptoms of Crohn's disease. This study provides evidence that the management of the gut microbiota can be a new therapeutic approach in the treatment of Crohn's disease.