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SOSIALISASI NANOEMULGEL ANTIBAKTERI KOMBINASI EKSTRAK TEMULAWAK DAN TEMUPUTIH UNTUK MENGATASI INFEKSI MRSA DI DESA PAYAMABAR Diding Pradita; Reza Destri Anggi; Azzura Ligo; Puspita Kusuma Wardani, Dea; Aminah, Nurul
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 5 No. 2 (2025): Desember 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v5i2.285

Abstract

Infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA) remain a major health concern due to their resistance to commonly used antibiotics, driving interest in safe and effective natural-based alternatives. This community service program introduced an antibacterial nanoemulgel formulated from combined extracts of Curcuma xanthorrhiza (temulawak) and Curcuma zedoaria (temu putih) to residents of Paya Mabar Village, Stabat District, Langkat Regency.  The activities included interactive education on the dangers of bacterial resistance, a demonstration of nanoemulgel preparation, and small group discussions to explore participants’ understanding of modern herbal-based treatments. Community members showed strong enthusiasm, reflected in active participation and improved awareness of antibiotic resistance and the potential of local medicinal plants. The outcomes indicated that a combined educational and hands-on approach effectively enhanced public knowledge of infection prevention and encouraged appreciation for natural ingredients as innovative health solutions. The community recognized nanoemulgel as a bridge between traditional wisdom and modern pharmaceutical technology.
Perbandingan Aktivitas Antioksidan Ekstrak Etanol,Etil Asetat, dan n-Heksan Daun Kayu Manis Hutan (Cinnamomum iners) Dengan Metode ABTS dan DPPH Hendri Faisal; Azzura Ligo; Rizka Hasmi Nasution
Jurnal Siti Rufaidah Vol. 3 No. 4 (2025): :Jurnal Siti Rufaidah
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jasira.v3i4.241

Abstract

. Indonesia possesses remarkable biodiversity, including numerous medicinal plant species traditionally employed as natural therapeutic agents. Among these, Cinnamomum iners is widely utilized and is known to contain diverse bioactive compounds with reported antimicrobial, anti-inflammatory, and free radical–scavenging activities. This research focuses onevaluate the antioxidant activity of ethanol, ethyl acetate, and n-hexane extracts of wild cinnamon leaves (Cinnamomum iners) using the ABTS and DPPH methods. Extraction was carried out using the maceration method. The antioxidant effectiveness was measured by analyzing the IC₅₀ values through free radical scavenging activity using the ABTS and DPPH methods with a UV-Vis spectrophotometer. The antioxidant activity of Cinnamomum iners leaves assessed using the ABTS method revealed that the ethanol extract exhibited very strong activity with an IC50 value of 7.56 ppm, followed by the ethyl acetate extract with moderate activity (IC50 103.59 ppm), and the n-hexane extract with weak activity (IC50 188.64 ppm). In contrast, the DPPH assay showed that the ethanol extract demonstrated moderate antioxidant activity with an IC50 value of 168.03 ppm, the ethyl acetate extract exhibited weak activity (IC50 400.5 ppm), and the n-hexane extract displayed no antioxidant activity (IC50 2373.2 ppm).