Nyoman Sadra Dharmawan
Laboratorium Patologi Klinik Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia

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HISTOLOGIC FEATURES OF GRANULOCYTE WHITE BLOOD CELLS AND PLATELET DISTRIBUTION WIDTH VALUES IN DOGS WITH DERMATITIS Patricia Amelia Debianti Wagut; Ni Ketut Suwiti; Sri Kayati Widyastuti; Nyoman Sadra Dharmawan; Ni Luh Eka Setiasih; I Made Kardena
Buletin Veteriner Udayana Bul. Vet. Udayana. June 2025 Vol. 17 No. 3
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i03.p35

Abstract

Dermatitis in dogs is an inflammation of the skin caused by parasites, bacteria, fungi and metabolic disorders, with severity varying from mild to severe. This condition triggers inflammation that affects granulocyte leukocytes, namely neutrophils, eosinophils and basophils, which can undergo necrosis. Necrosis is characterized by changes in nuclear morphology, such as pycnosis, karyorexis, and karyolysis due to irreversible cell injury. In addition, Platelet Distribution Width (PDW) values reflect variations in platelet size and are often associated with inflammatory activity. This study analyzed the histological features and differences in necrotizing leukocyte counts and PDW values in dogs with mild and severe dermatitis. The results showed that necrotizing neutrophils in mild dermatitis (4.9 ± 5.2) were lower than those in severe dermatitis (5.4 ± 3.3), but the results of the independent t-test showed that the difference was not significant (P > 0.05). The opposite situation in eosinophils and basophils, where eosinophils that experienced necrosis in mild dermatitis (2.5 ± 11) were higher than those in severe dermatitis (0 ± 0), while basophils that experienced necrosis were higher in mild dermatitis (9.6 ± 17) than in severe dermatitis (0 ± 0), but the results of the independent t-test showed that the difference was significant (P < 0.05). The PDW value in mild dermatitis (15 ± 2.4) was greater than that in severe dermatitis (14.5 ± 2), but not significantly different (P > 0.05), it can be concluded that the severity of dermatitis does not affect platelet size. Further research needs to be done on health status by looking at other indicators such as the presence of lymphocytes and monocytes in dogs with mild derrmatitis and severe dermatitis.
STUDY OF ANTIBIOTIC USAGE IN PIG FARMING IN SEBATU VILLAGE, GIANYAR REGENCY, BALI Emia Pepa Yosa Br Ginting; Kadek Karang Agustina; Tjok Gde Oka Pemayun; Romy Muhammad Dary mufa; I Wayan Masa Tenaya; I Made Sukada; Nyoman Sadra Dharmawan
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2025 Vol. 17 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i01.p12

Abstract

The main cause of antibiotic resistance is the misuse and excess of antibiotics. Other factors are misunderstanding of antibiotic use, inappropriate antibiotic dosage, the use of broad-spectrum antibiotics and antibiotics sold freely without a doctor's prescription. The purpose of this study was to determine the percentage of antibiotic use among pig farms, the types of antibiotics used and the status of antibiotic use by pig farmers in Sebatu Village, Tegallalang District, Gianyar Regency, Bali. The study used observational and interview methods in the form of questionnaires distributed to pig farmers. Data were analyzed descriptively and then displayed in tables and figures. The percentage of respondents who used antibiotics under the supervision of a veterinarian was 56.67% (17/30 respondents) and 43.33% (13/30 respondents) of pig farmers provided independent treatment for livestock without supervision from a veterinarian. (33.33%) pig farmers obtained antibiotics from drug stores, (10%) from other farmers. The types of antibiotics used were the Tetracycline group (92.3%); Penicillin (30.7%); Sulfonamides (38.4%); Aminoglycosides (23.0%). Selecting antibiotics based on the needs of sick animals (26.67%); Selected by drug sellers (16.67%); dosage determined by drug brochures (30%); Previous experience (13.33%); Farmers' knowledge of antibiotics and their functions (63.33%); do not know (36.67%) and farmers already know that using antibiotics must be under the supervision of a veterinarian (60%); do not know (40%). The percentage of pig farmers who use antibiotics in Sebatu Village, Tegallalang District, Gianyar Regency, Bali reached 43.33% (13 farmers) independently without the supervision of a veterinarian with various types of antibiotic groups.
EPIDEMIOLOGY AND HEMATOLOGICAL IMPACT OF TICK INFESTATION IN BALI CATTLE: A CROSS-SECTIONAL STUDY IN BONE REGENCY, INDONESIA Nurul Fajriani Makkawaru Shaifuddin; Ida Ayu Pasti Apsari; Nyoman Sadra Dharmawan
Buletin Veteriner Udayana Bul. Vet. Udayana. October 2025 Vol. 17 No. 5
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i05.p22

Abstract

A cross-sectional study was conducted to determine the prevalence, associated risk factors, and hematological impact of tick infestation on Bali cattle in Bone Regency, South Sulawesi, Indonesia. A total of 296 cattle from 10 districts were examined using purposive sampling. Data on risk factors (sex, age, management system, control methods) were collected via farmer questionnaires. Hematological profiles were assessed from infested animals. The overall prevalence of tick infestation was high at 60.13%, with significant variation between districts, ranging from 34.61% (Tanete Riattang Barat) to 89.66% (Palakka). Multivariate analysis identified sex, management system, and tick control practices as significant risk factors (p < 0.05) associated with infestation, whereas age was not a significant predictor. Despite the high infestation rate, all measured hematological parameters in infested cattle fell within normal physiological ranges. These findings highlight a high burden of tick infestation in the region and underscore the critical need for targeted control strategies focused on the identified risk factors to improve animal health and productivity.