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All Journal Unesa Journal of Chemistry
Pradikatama Prihantono, yafet
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology

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OPTIMASI VARIASI KONSENTRASI TWEEN 80 PADA FORMULASI NANOEMULSI KOMBINASI EKSTRAK DAUN PEGAGAN DAN DAUN KELOR lahardo, devanus; Pradikatama Prihantono, yafet
Unesa Journal of Chemistry Vol. 14 No. 3 (2025): Vol 14 No 3 (2025) (on progress)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, Surabaya State University, located at Jl Ketintang, Surabaya, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ujc.v14n3.p83-89

Abstract

Abstract. This study aims to optimize the nanoemulsion formulation of combined extracts of Centella asiatica and Moringa oleifera leaves using varying concentrations of Tween 80 as a surfactant. Three formulas were prepared with 8%, 10%, and 12% Tween 80. Physical evaluations included particle size, pH, and viscosity. Results showed that increasing Tween 80 concentration increased particle size and viscosity, while pH remained relatively stable. The 8% Tween 80 formula yielded the most optimal result with the smallest particle size and suitable viscosity for topical application. One-way ANOVA revealed significant differences in particle size and viscosity, but not in pH. These findings indicate that Tween 80 concentration affects the physical stability of the nanoemulsion Key words: kelor leaves, pegagan leaves, nanoemulsion, tween 80
Co-Authors Lahardo, Devanus