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All Journal Unesa Journal of Chemistry Borneo Journal of Pharmacy
Lahardo, Devanus
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology Medicine & Pharmacology

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Ethnomedicine Study of Medicinal Plants for Therapy of Elderly Sleep Disorders in Tengger Tribe Lahardo, Devanus; Ekasari, Wiwied; Widyawaruyanti, Aty
Borneo Journal of Pharmacy Vol. 7 No. 3 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i3.7272

Abstract

Ethnomedicine offers valuable insights into plant-based therapies, potentially leading to the discovery of novel drugs. Sleep disturbances, including difficulty falling asleep, maintaining sleep, and early morning awakening, are prevalent among the elderly population and can significantly worsen Alzheimer's disease progression. This study explores the medicinal plants utilized by the Tengger tribe's elderly population for treating sleep disorders. Employing a mixed-methods approach, the study involved qualitative data collection through snowball sampling and in-depth interviews with 99 elderly participants and three traditional healers of the Tengger tribe. Quantitative data was obtained through questionnaires administered during field surveys. Participants were selected based on specific criteria: elderly individuals over 60 years of age, native Tengger tribe members with a history of using medicinal plants for sleep disorders; traditional healers were required to be native Tengger tribe members with knowledge passed down through generations. The study identified a total of 11 medicinal plants used for sleep disorders. Five plant species emerged as the most dominant based on the highest citation value (FC) analysis: kale (Ipomoea reptans), agarwood (Aquilaria malaccensis), sintok (Cinnamomum sintoc), Broadleaf plantain (Plantago major), and soursop (Annona muricata). The most commonly used plant parts were leaves, bark, and roots. Traditional preparation methods included boiling and burning the plant materials. Notably, knowledge of these medicinal plants is primarily transmitted orally within the community. Our findings highlight five medicinal plants employed by the Tengger elderly to manage sleep disorders, with limited documented evidence of their efficacy.
OPTIMASI VARIASI KONSENTRASI TWEEN 80 PADA FORMULASI NANOEMULSI KOMBINASI EKSTRAK DAUN PEGAGAN DAN DAUN KELOR lahardo, devanus; Pradikatama Prihantono, yafet
Unesa Journal of Chemistry Vol. 14 No. 3 (2025): Vol 14 No 3 (2025) (on progress)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, Surabaya State University, located at Jl Ketintang, Surabaya, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ujc.v14n3.p83-89

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Abstract. This study aims to optimize the nanoemulsion formulation of combined extracts of Centella asiatica and Moringa oleifera leaves using varying concentrations of Tween 80 as a surfactant. Three formulas were prepared with 8%, 10%, and 12% Tween 80. Physical evaluations included particle size, pH, and viscosity. Results showed that increasing Tween 80 concentration increased particle size and viscosity, while pH remained relatively stable. The 8% Tween 80 formula yielded the most optimal result with the smallest particle size and suitable viscosity for topical application. One-way ANOVA revealed significant differences in particle size and viscosity, but not in pH. These findings indicate that Tween 80 concentration affects the physical stability of the nanoemulsion Key words: kelor leaves, pegagan leaves, nanoemulsion, tween 80
Co-Authors Aty Widyawaruyanti Pradikatama Prihantono, yafet Wiwied Ekasari