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All Journal Cendana Medical Journal
Dupe, Shita Anggenella
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Health Professions Medicine & Pharmacology Public Health

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ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT 70% OF FALOAK BARK (Sterculia quadrifida R.Br) ON Klebsiella Pneumoniae BACTERIA Dupe, Shita Anggenella; Nurina, Rr. Listyawati; Damanik, Efrisca M. Br; Pakan, Prisca Deviani
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.27147

Abstract

Introduction: Pneumonia is a common lower respiratory infection affecting all ages, caused by bacteria, viruses, fungi, or parasites. Klebsiella pneumoniae is a bacterial cause showing high antibiotic resistance, complicating treatment. As a result, alternative treatments using medicinal plants with antibacterial properties are needed. One promising plant is faloak (Sterculia quadrifida R.Br), traditionally used in herbal medicine and believed to have potential antibacterial effects worth further investigation. Methods: This study employed a true experimental method with a post-test only control group design. The treatment groups were given 70% ethanol extract of faloak bark at various concentrations (100%, 50%, 25%, 12.5%, 6.25%, and 3.12%). There were also a positive control group (meropenem antibiotic) and a negative control group (sterile distilled water). Data were analyzed using the Kruskal-Wallis test. Results: The 70% ethanol extract of faloak bark showed antibacterial activity against Klebsiella pneumoniae, with a significance value of p = 0.002 (< 0.05), indicating a significant difference in the inhibition zone diameters. Discussion: The extract demonstrated antibacterial properties and the ability to inhibit the growth of Klebsiella pneumoniae. Conclusion: The 70% ethanol extract of faloak bark (Sterculia quadrifida R.Br) exhibits antibacterial activity against Klebsiella pneumoniae.
Co-Authors Damanik, Efrisca M. Br Nurina, Rr. Listyawati PAKAN, PRISCA DEVIANI