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Penetapan Kadar Total Fenol dan Total Flavonoid pada Lotion Berbahan Ekstrak Daun Sisrsak (Annona muricata) dan Kulit Buah Naga Merah (Hylocereus polyrhizus) Menggunakan Spektrofotometri UV–VIS Siregar, Suci Rahmadani; Suprianto; Chandra Pranata; Marbun, Intan Coni Caroline
Jurnal Indah Sains dan Klinis Vol 6 No 3 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i3.04

Abstract

Background: Phenolic and flavonoid compounds from soursop (Annona muricata) leaves and red dragon fruit (Hylocereus polyrhizus) peel have potential applications in lotion formulations; therefore, their quantification is important for quality evaluation. Objective: To determine total phenolic content (TPC) and total flavonoid content (TFC) in lotion formulations containing combined plant extracts and to assess the analytical method performance. Method; Four formulations were prepared: F0 (without extract), F1 (0.5% + 0.5%), F2 (1.0% + 1.0%), and F3 (1.5% + 1.5%). TPC was measured using the Folin–Ciocalteu method (mg GAE/g) and TFC using the AlCl₃ colorimetric method (mg QE/g). Method validation included repeatability (%RSD, n = 6) and spike-recovery accuracy at 80–120%. Results: The method showed good precision (%RSD 1.08% for TPC and 1.21% for TFC) and acceptable accuracy with recoveries of 98–102%. F0 showed non-detectable values, while increasing extract concentration resulted in higher TPC (3.82 ± 0.14 to 9.71 ± 0.33 mg GAE/g) and TFC (0.86 ± 0.05 to 2.35 ± 0.10 mg QE/g). Differences among formulations were statistically significant (p < 0.05). Conclusion: The UV–Vis method is suitable for determining TPC and TFC in lotion matrices, and higher levels of combined extracts significantly increase both parameters, supporting their use for quality standardization of herbal lotions.
Workload Analysis of Pharmacists at Tanjung Selamat General Hospital, Langkat, 2025 Nemas Adelina Lubis; Rahmad Gurusinga; Chandra Pranata
JURNAL KESMAS DAN GIZI (JKG) Vol. 8 No. 2 (2026): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/r470a461

Abstract

Pharmaceutical personnel play a crucial role in ensuring the quality of healthcare services in hospitals. A high workload, if not properly managed, can negatively affect performance, patient safety, and service quality. This study aims to analyze the workload of pharmacists at the Pharmacy Installation of Tanjung Selamat General Hospital, Langkat, focusing on four main variables: the type and number of tasks, limitations in human resources, duration and work shift patterns, and work adjustment strategies.This study employed a qualitative approach using a descriptive method. Data were collected through in-depth interviews with one key informant (Head of the Pharmacy Installation) and three triangulation informants (Pharmaceutical Technical Personnel and Pharmacy Assistants). Data analysis was conducted through data reduction, data presentation, and conclusion drawing.The results indicate that pharmacists and pharmaceutical personnel at Tanjung Selamat General Hospital handle various types of tasks, including administrative and non-clinical duties such as medical waste management. The limited number of staff leads to task overlap, uneven shift distribution, and an increased risk of work fatigue. The 24-hour shift system has not been optimally implemented due to the disproportionate distribution of personnel. Work adjustment strategies, such as task prioritization and teamwork, have been applied; however, they remain individual-based and are not yet supported by a structured managerial system.In conclusion, the workload of pharmaceutical personnel is considered high and complex. The hospital needs to increase staffing levels, evaluate the shift system, and strengthen supporting systems such as standard operating procedures (SOPs) and information technology. Adjustments in human resource management policies are essential to maintain work efficiency and the quality of pharmaceutical services