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All Journal International Journal of Public Health Science (IJPHS) Journal of Current Health Sciences
Devi, Joti
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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A Systematic Review of Regional Practices and Nutraceutical Management Strategies in the treatment of Dengue Fever Sazu, MD. Hassan; Chowdhury, Atikah Islam; Iqbal, Hrishik; Hassan, Md Abul; Devi, Joti; Syrmos, Nikolaos
Journal of Current Health Sciences Vol. 6 No. 1: 2026
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/jchs.2026145

Abstract

Dengue fever (DF), one of the common mosquito-borne viral diseases in humans, is still a serious public health problem throughout the world with special emphasis on tropical and subtropical areas. Though there are significant morbidity and mortality, treatments are mainly supportive; thus, additional approaches that may decrease disease severity are warranted. There is accumulating evidence that micronutrient status may potentially affect immune responses and clinical outcome in DF, thus supporting more general observations of nutritional modulation of susceptibility to, disease progression or outcome from infectious diseases. To assess this possibility, we considered the literature on micronutrient supplementation for DF patients. Vitamin C, Vitamin D, vitamin E and zinc were reported in some studies to potentially reduce recovery time, improve platelet trends and decrease severity of illness. In contrast, folic acid did not have any significant effects on clinical end points. However, as the available literature is fraught with obvious weaknesses such as small sample size, differing results between studies and an inadequate assessment of patients' nutritional status at the outset, any clinical recommendations are weakened. Although vitamins D and E have shown promise in preliminary trials, the existing body of evidence is not clear and coherent. This review addresses the increasing attention on micronutrient interventions in DF as well as the necessity of good quality randomized controlled trials that provide better exposure about their therapeutic effects and evidence-based recommendations.
Nipah virus as an emerging threat: mutational dynamics, pathogenesis, and advances in vaccine development- a systematic review Afrin, Sadia; Mahedi, Md. Rezwan Ahmed; Radia, Asma Akhter; Devi, Joti
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.22365

Abstract

Nipah virus (NiV) is an emerging zoonotic pathogen with significant pandemic potential. Large outbreaks, such as in Malaysia, required the culling of over one million pigs to control transmission. However, the epidemiology of NiV among animal hosts, including pigs, horses, and bats, remains incompletely understood. NiV infection primarily affects the respiratory and nervous systems, causing severe pneumonia, vasculitis, and meningitis, while encephalitis may be mild or infrequent in some cases. This systematic review summarizes current evidence on NiV mutational variation, pathogenesis, treatment strategies, and vaccine development up to 2022. Data were collected from major databases, including PubMed, PMC, and Cochrane Library. Due to limited therapeutic options, NiV management relies mainly on supportive care, as no approved vaccines or specific antiviral treatments are available for humans or livestock. Preventive strategies focus on reducing zoonotic transmission, particularly by minimizing contact between livestock and bat-contaminated food sources, and improving farm management practices. Early detection and continuous surveillance of high-risk populations and animal reservoirs are essential for outbreak control. Current vaccine research targets viral antigens using subunit and vector-based approaches. Overall, further studies are urgently needed to develop effective vaccines and antiviral therapies for NiV infection.
Co-Authors Afrin, Sadia Chowdhury, Atikah Islam Hassan, Md Abul Iqbal, Hrishik Mahedi, Md. Rezwan Ahmed Radia, Asma Akhter Sazu, MD. Hassan Syrmos, Nikolaos