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Investigation of Total Tannin, Phenolic & Flavonoid Content of Araucaria Heterophylla for Antioxidant Source Ghosh, Ankita; Paul, Shimanta; Ghosh, Susmita; Akter, Sadia; Mahedi, Rezwan Ahmed; Afrin, Sadia; Hasan, Akayed; Hasan, Ali Mohamod Wasaf; Sayeed, Md Abu; Syrmos, Nikolaos
Journal of Tropical Pharmacy and Chemistry Vol. 8 No. 2 (2024): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v8i2.634

Abstract

Secondary metabolites, a type of bioactive molecule with many functions, are abundant in Araucaria Heterophylla. The secondary metabolites flavonoids, phanolic acid, and tannin have been found to have anti-inflammatory, antiviral, antibacterial, antioxidant, and anticancer properties. The present study was conducted to analyze the phytochemical and determine the total flavonoid, tannin, phenolic content of Araucaria Heterophylla leaves extract using two different solvents (methanol and dichloromethane) using UV-Vis spectrophotometric. The plant was identified by NHB (ID No: DACB 48435) and prepared the methanolic extract to estimate the total content of tannin, phenolic & flavonoid in Araucaria Heterophylla. Folin-ciocaltu method was used for the investigation of total phenolic and tannin content. The A. heterophylla leaf methanolic and dichloromethane extract had remarkable antioxidant effects due to its high flavonoid and phenolic content. This standardised bioactive ingredient could be used in many phytopharmaceutical preparations
Human Metapneumovirus: A Critical Review of Its Impact on the Immune System and Clinical Implications Shahidul Islam, Syed Mahmood; Laskar, Nourjahan; Reza, Md.Shajalal; Ahmed, MD. Faisal; Iqbal, Hrishik; De Guia, Lemar Cardenas; Syrmos, Nikolaos
Journal of Current Health Sciences Vol. 5 No. 2: 2025
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/jchs.2025111

Abstract

Human Metapneumovirus (HMPV) became known in 2001 as a major respiratory pathogen which triggers acute respiratory tract infections (ARTIs) in the population with particular impact on infants and elderly patients and individuals with impaired immunity. HMPV was recently identified but retrospective analyses show this virus has existed unnoticed throughout previous decades starting from the 1950s. The respiratory tract pathogen HMPV exists within the Pneumoviridae family with genomic and structural relationships to respiratory syncytial virus (RSV). The virus manifests differently from delicate upper respiratory conditions to dangerous bronchiolitis and pneumonia within the lower respiratory system. Medical practitioners discover it difficult to identify HMPV due to identical viral symptoms but RT-PCR now enhances testing precision. HMPV has a seasonal pattern which reaches its peak during late winter and spring through airborne respiratory droplet transmission. Most people acquire the virus before their fifth year but continued infections happen as natural protection weakens so there remains an urgent need to develop safe treatments and vaccines against HMPV. FDA-approved antiviral drugs along with vaccines do not exist for treatment so healthcare professionals must provide supportive care only. Studies of HMPV's spread have improved yet scientists have not resolved fundamental questions about lineage immunity protection and virus immune evasion behaviors and persistent immune responses. The prevention of HMPV transmission requires proper hand hygiene practice together with respiratory etiquette. Multidisciplinary research needs continuous investigation because it helps tackle the worldwide burden of HMPV while developing specific prevention methods for this enduring public health threat that affects vulnerable populations.
Situation Report of Clinical and Climatic Pattern Changes in Dengue Outbreaks in Bangladesh 2024–2025 Hossain, Tanvir; Chayan, Famous Uddin; Iqbal, Hrishik; Alam, Fahadul; Syrmos, Nikolaos
Journal of Current Health Sciences Vol. 5 No. 4: 2025
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/jchs.2025137

Abstract

Dengue is still a big public health problem in Bangladesh, and the number of cases has risen rapidly in the last several years.  This review integrates epidemiological, clinical, and environmental data to clarify the determinants contributing to the country's dengue crisis.  A systematic literature search from 2001 to 2025 was carried out using PubMed and the Cochrane Library, resulting in 50 pertinent papers regarding dengue epidemiology, transmission dynamics, and health effects in Bangladesh.  The first report of dengue was in 1960, and the first epidemic was in 2000.  Dengue has since become endemic, with huge outbreaks in 2019 (101,354 cases; 164 deaths) and a terrible peak in 2023 (321,179 hospitalizations; 1,705 deaths).  Aedes aegypti has had good reproduction conditions because of changing weather, rising temperatures, unpredictable rainfall, and fast, unplanned urbanization.  Epidemiological changes encompass ongoing year-round transmission, an increase in secondary infections attributable to several serotypes, and a geographical spread from urban Dhaka to semi-urban and rural areas, including the Cox’s Bazar refugee camps.  In clinical practice, patients are increasingly diagnosed with atypical or "expanded dengue syndrome," and mortality is closely linked to shock and subsequent infections.  The expenses to society for each incidence are high, averaging US$479 in urban Dhaka.  People who are more likely to get sick or have mental health problems are youngsters, pregnant women, and the elderly.  Evidence shows that climate change and urbanization are working together to lengthen the dengue season, make epidemics worse, and put a load on Bangladesh's healthcare system.  To lessen the growing threat, it is important to improve surveillance, vector management, and investment in healthcare resilience.  
Investigating The Awareness of Food Safety Among Buyers and Sellers in a Local Market - a Taste of Safety Mahmood Shahidul Islam, Syed; Laskar, Nourjahan; Afrin, RPh. Sadia; Ahmed Mahed, RPh. Md. Rezwan; Musarrat, Zahra; Syrmos, Nikolaos
Journal of World Science Vol. 2 No. 12 (2023): Journal Of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v2i12.512

Abstract

This research aims to assess the food safety knowledge among buyers and sellers in the city market, particularly in the post-pandemic context. The study focuses on understanding the extent to which individuals adhere to food safety and hygiene measures. The method used in this research is quantitative and conducted in the Mohammadpur city market, involving 101 buyers and 101 sellers selected for interviews. The research employed a structured questionnaire to gather information on participants' age, gender, level of education, and training on food safety. The results of the study indicate that a total of 202 participants, with an average age of 38.16 years, were involved. Gender distribution shows that the majority of buyers (72%) and sellers (87%) were male. The analysis demonstrates a significant relationship (p<0.001) between the level of education, training on food safety, and overall knowledge of food safety among buyers. This research implies the need for enhanced monitoring and regulation of activities conducted by food vendors to reduce potential risks and the transmission of foodborne illnesses. The implementation of regulations, promotion of hygienic practices, and food safety control measures are crucial steps to achieve this objective. Local authorities, with smooth execution of their duties, play a vital role in ensuring the effectiveness of these measures.