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All Journal Indonesian Journal of Health Science Journal of Innovative and Creativity
Asriyani Abdullah
Universitas Khairun
Dentistry Education Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Giardiasis: Etiologi, Patofisiologi, Morfologi, Diagnosis, dan Pengobatan Asriyani Abdullah; Insani Fitrahulil Jannah
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.4706

Abstract

Giardiasis adalah penyakit infeksi yang disebabkan oleh Giardia lamblia (G. duodenalis atau G. intestinalis), dan masih menjadi masalah kesehatan masyarakat di negara berkembang dengan kondisi sanitasi yang buruk. Penularan terjadi melalui jalur fekal-oral, baik secara langsung maupun tidak langsung. Infeksi ini dapat bersifat asimtomatik hingga gejala kronis yang dapat menyebabkan malnutrisi, penurunan berat badan, dan dehidrasi. Diagnosis konvensional mengandalkan pemeriksaan mikroskopis tinja, meskipun teknik ini memiliki keterbatasan dalam sensitifitas dan spesifisitas. Maka metode imunologis atau molekuler seperti PCR diperlukan sebagai pelengkap, namun aksesnya masih terbatas. Pengobatan tergantung pada keadaan atau kondisi pasien, namun metronidazol dan tinidazole masih menjadi pilihan. Pencegahan jangka panjang melibatkan peningkatan sanitasi, edukasi masyarakat, dan pengembangan vaksin. Penelitian masa depan harus difokuskan pada pengembangan metode diagnosis yang lebih sensitif dan praktis, pemahaman terhadap mekanisme resistensi obat, serta eksplorasi target baru untuk terapi dan vaksin.
From environment to lung: A literature review on exposure risk factors and prevention of Aspergilosis Asriyani Abdullah; Insani Fitrahulil Jannah; Elfira Buamona
Indonesian Journal of Health Science Vol 6 No 2 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i2.2144

Abstract

Aspergillosis comprises a spectrum of pulmonary diseases caused by inhalation of Aspergillus spores from the environment in individuals with immunological vulnerability or structural lung damage. This review summarizes major environmental sources of exposure (soil, compost, hospital ventilation and water systems, and construction activities), key host and environmental risk factors, and environmental and clinical prevention strategies. Multiple studies report increased airborne spore counts and higher incidence of invasive aspergillosis among haematology patients during hospital construction when protective ventilation and HEPA filtration are insufficient. Principal host risk factors include prolonged neutropenia, haematological malignancies, transplantation, immunosuppressive therapy, post‑tuberculosis cavities, severe COPD, and other chronic lung diseases. Climate change and natural disasters are thought to enhance the distribution of airborne fungal spores, although quantitative data specifically linking these events to aspergillosis remain limited. Effective prevention requires an integrated approach combining environmental control, targeted antifungal prophylaxis, screening in patients with structural lung disease, patient education, and stewardship to address azole resistance within a One Health framework.
Co-Authors Elfira Buamona Insani Fitrahulil Jannah