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Faktor Gaya Hidup sebagai Prediktor Kualitas Hidup pada Pasien Luka Kaki Diabetik: Studi Cross-Sectional di Indonesia Restu Anisa Putri; Rani Sauriasari; Atika Wahyu Puspitasari
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.53487

Abstract

Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus (DM) that significantly impacts patients' quality of life. Lifestyle factors, particularly smoking status and physical activity, are important modifiable factors to support improvement of this condition. This study aims to analyze the relationship between these two factors and the quality of life of DFU patients in Indonesia. A predictive cross-sectional study was conducted on 70 patients undergoing treatment at six branches of the Diabetic Wound Care Home Clinic in the Greater Jakarta area during March–May 2025. Quality of life was measured using the Indonesian version of the Diabetic Foot Ulcer Scale-Short Form (DFS-SF). Analysis was performed using the chi-square test for bivariate associations and multivariate logistic regression, controlling for confounding variables. The results showed that most patients did not smoke (74.3%) and did not exercise regularly (70.0%). Smoking status was significantly associated with quality of life (p=0.042), while physical activity showed a trend towards significance (p=0.060). Multivariate analysis identified physical activity as a predictor of quality of life (OR=5.30; 95% CI: 0.96–29.14; p=0.055), with patients who did not exercise being 5.3 times more likely to experience low quality of life. Smoking status showed a paradoxical result (OR=0.12; 95% CI: 0.02–0.82; p=0.030), which requires cautious interpretation. Physical activity also significantly impacted the domains of dependency/activities of daily living (p=0.001) and physical health (p=0.002). These findings emphasize the importance of integrating physical activity promotion and healthy lifestyle interventions in the holistic management of patients with LKD to support improved quality of life.
Analysis of Predictors Associated with Acid Suppressant Drug Related Problems (DRPs) among Inpatients at Dr. Mintohardjo Naval Hospital Deki Yuliya Putra; Atika Wahyu Puspitasari; Siti Fauziyah
Eduvest - Journal of Universal Studies Vol. 6 No. 4 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i4.53073

Abstract

The use of gastric acid suppressants such as Proton Pump Inhibitors (PPI) and Histamine-2 Receptor Antagonists (H2RA) is very common in inpatient settings, but inappropriate use is often found, posing risks to patient safety and cost efficiency. This study aims to analyze the relationship of predictors (age, number of drugs, number of comorbidities, and length of stay) to the occurrence of Drug-Related Problems (DRPs) in inpatients using gastric acid suppressants. This study was an observational study with a cross-sectional design was conducted retrospectively using patient medical record data at Rumkital Dr. Mintohardjo from January to December 2024. A sample of 432 patients was taken using a simple random sampling technique based on inclusion criteria. DRPs were identified using the Pharmaceutical Care Network Europe (PCNE) V9.0 instrument. Data analysis used the chi-square test for bivariate analysis and binary logistic regression for multivariate analysis. DRP characteristics were dominated by treatment safety issues (49.1%), particularly adverse drug events, with the most frequent drug interaction being ranitidine and ketorolac. Bivariate analysis showed that length of stay (p=0.105), and number of drugs (p=0.001) significantly influenced the number of DRPs. Multivariate analysis identified the number of drugs as the most influential predictor; inpatients receiving ≥10 drugs had a 2.580 times higher risk of experiencing DRPs (p=0.003; OR 2,580; 95% CI 1.396-4.779)