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All Journal Biology, Medicine, & Natural Product Chemistry
Oyewusi, Adekilekun Habeebat
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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GC-MS Determination of Bioactive Components with Their Biological Activities of Olax subscorpioidea (Olacaceae) Odoma, Saidi; Adekilekun, Ajibola Habeebulahi; Onohuean, Hope; Funso, Funso-Babarimisa; Oyewusi, Adekilekun Habeebat; Hamid, Abdulmumeen Amao
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1437-1449

Abstract

Medicinal plants have been an integral part of healthcare, particularly in Africa, where over 80% of the population relies on traditional herbal medicine. This research focuses on Olax subscorpioidea, a plant recognized for its extensive pharmacological activities, including anti-inflammatory, antioxidant, antidiabetic, and analgesic properties. The study aimed to identify the bioactive compounds present in the leaf extract of O. subscorpioidea using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. The plant was collected, dried, and extracted with methanol, leading to the identification of 199 compounds, including phenols, terpenoids, flavonoids, and fatty acids, some of which possess significant biological activities. Toxicological studies indicated a safe dosage with no adverse effects observed in mice. This research underscores the potential of O. subscorpioidea as a source of novel therapeutic agents, necessitating further isolation and characterization of its bioactive constituents to explore their pharmacological potentials comprehensively.
Co-Authors Adekilekun, Ajibola Habeebulahi Funso, Funso-Babarimisa Hamid, Abdulmumeen Amao Odoma, Saidi Onohuean, Hope