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All Journal Jurnal Kedokteran Brawijaya Journal of Anaesthesia and Pain
Auzan, Asyrafly
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Health Professions Medicine & Pharmacology

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Comparison of General Anesthesia vs Spinal Anesthesia on Post Operative Pain After Hysterectomy - A Systematic Review and Meta-analysis Lalchanzani, Jawaharlal Akbar; Faida, Nova Auliyatul; Auzan, Asyrafly
Journal of Anaesthesia and Pain Vol. 7 No. 1 (2026): January
Publisher : Faculty of Medicine, Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Hysterectomy is among the most frequently performed major surgical procedures. General anesthesia (GA) remains the most commonly used technique. The choice between GA and spinal anesthesia (SA) can significantly impact patient outcomes, particularly pain control and the incidence of postoperative nausea and vomiting. This systematic review and meta-analysis aims to compare the effects of GA versus SA on duration of operation, pain intensity, postoperative analgesic consumption, and the incidence of nausea and vomiting in patients undergoing hysterectomy. Methods: This systematic review and meta-analysis assessed operative duration, pain intensity, postoperative analgesic consumption, and the incidence of nausea and vomiting in GA versus SA for hysterectomy. Data were analyzed using random‑effects models.   Result: Eight studies, including a total of 1,054 patients, were analyzed. Postoperative pain intensity was significantly higher in the GA group based on the Visual Analogue Scale (VAS) score compared to the SA group (MD, 0.84; 95% CI, [0.11, 1.56]; p = 0.02, I² = 56%). No significant differences were found for other outcomes: operative time (MD, 1.95; 95% CI, [-1.30, 5.19]; p = 0.24, I² = 10%), analgesic consumption (MD, -7.48; 95% CI, [-20.38, 5.43]; p = 0.26, I² = 96%), and nausea/vomiting events (RR, 0.71; 95% CI, [0.48, 1.05]; p = 0.09, I² = 0%). Conclusion: SA showed significant reductions in pain scores compared with GA, suggesting potential benefits for pain relief. However, the choice of anesthesia should be guided by patient-specific factors, the complexity of the surgery, and clinical preferences.
Sagittal Knee Alignment Is Associated with Reduced Knee Flexion Range of Motion in Asymptomatic Elderly: A Cross-Sectional Study Mustamsir, Edi; Putra, Domy Pradana; Aji, Aulia Pandu; Firladi, Haidar Abror; Auzan, Asyrafly; Sasongko, Armabar Dwipantara; Tegar, Bintang Taqwa Nan
Jurnal Kedokteran Brawijaya Vol. 34 No. 2 (2026): Article in Press 2026
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Knee alignment affects lower limb biomechanics and functional knee movement. However, the relationship between knee alignment and knee flexion range of motion (ROM) in healthy populations, particularly across different age groups, remains unclear. To compare coronal and sagittal knee alignment and knee flexion ROM between healthy young adults and elderly individuals, and to examine the association between knee alignment and knee flexion ROM using clinical goniometric assessment. This cross-sectional study included 64 healthy participants (32 young adults aged 20–24 years and 32 elderly individuals aged ≥60 years). Coronal and sagittal knee alignment and active knee flexion ROM were measured using a goniometer. Group differences were analyzed using independent t-tests and Chi-square tests, and associations between alignment categories and knee flexion ROM were assessed using the Kruskal-Wallis test. Elderly participants showed a higher prevalence of coronal varus alignment and sagittal flexion contracture compared with young adults. Mean knee flexion range of motion was significantly lower in elderly participants than in young adults (127.4±4.7° vs 137.6±4.4°, p<0.001). Coronal knee alignment was not significantly associated with knee flexion ROM in either young adults (p=0.056) or elderly participants (p=0.476). In contrast, sagittal knee alignment demonstrated a significant association with knee flexion ROM in elderly participants (p=0.017), whereas no significant association was observed in the young adult group (p=0.922). Sagittal knee alignment, rather than coronal alignment, correlates with reduced knee flexion range of motion in healthy elderly individuals. A straightforward clinical evaluation of sagittal alignment may assist in detecting early functional deterioration in ageing populations.
Co-Authors Aji, Aulia Pandu Edi Mustamsir Faida, Nova Auliyatul Firladi, Haidar Abror Lalchanzani, Jawaharlal Akbar Putra, Domy Pradana Sasongko, Armabar Dwipantara Tegar, Bintang Taqwa Nan