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All Journal Jurnal Klinik dan Riset Kesehatan
Trisnawati, Lydia
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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KORELASI ANTARA RESISTENSI ANTIMIKROBA DENGAN KEMAMPUAN MEMBENTUK BIOFILM PADA ISOLAT PSEUDOMONAS AERUGINOSA DARI SAMPEL SPUTUM ETT DI RUANG RAWAT INTENSIF RSUD DR. SAIFUL ANWAR Ruliatna, Etty Fitria; Ruliatna, Fitria; Trisnawati, Lydia; Kusumaningrum, Yuyun
Jurnal Klinik dan Riset Kesehatan Vol 5 No 2 (2026): Volume 5 No 2, Edisi Februari 2026
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.2.3

Abstract

Background: Pseudomonas aeruginosa is a prominent pathogen responsible for hospital-acquired infections. Its pathogenic potential is primarily driven by antimicrobial resistance and the ability to form biofilms. Aim: To examine the correlation between antimicrobial resistance patterns and the biofilm-forming ability of Pseudomonas aeruginosa isolated from endotracheal tube (ETT) sputum specimens. Methods: This analytic cross-sectional study used sputum samples from ICU patients with ETT. Biofilm detection was done using the microtiter plate method, and antimicrobial susceptibility was tested using Vitek. Results: Of the 23 multidrug-resistant (MDR) isolates identified, 45.5% demonstrated biofilm-forming ability, while 54.5% did not. Statistical analysis using the Chi-square test revealed no significant association between antimicrobial resistance and biofilm formation. Conclusion: There was no significant correlation between multidrug resistance and biofilm production in Pseudomonas aeruginosa isolates from ETT sputum samples.
Co-Authors Kusumaningrum, Yuyun Ruliatna, Etty Fitria Ruliatna, Fitria