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All Journal International Journal of Health, Engineering and Technology
Malinda Apriliani
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Evaluation Of The Rationality Of Antibiotic Use In Hospitalized Adult Patients With UTI Diagnosis On Clinical Outcome At Dr. Moewardi Regional Hospital Malinda Apriliani; Kharisma Jayak Pratama; Niken Luthfiyanti
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.651

Abstract

Urinary Tract Infection (UTI) is a common infection with high antibiotic resistance due to irrational use.  To assess the rationality of antibiotics in adult inpatients with UTI at Dr. Moewardi Regional General Hospital using the Gyssens method, ATC/DDD patterns, and their relationship with clinical outcomes. A retrospective descriptive observational study of medical records of 50 acute pyelonephritis patients (population 270, Slovin sample e=10%, consecutive sampling), collected in December 2025. LPD medical records; analysis: Gyssens (qualitative Permenkes 28/2021), ATC/DDD (quantitative), Fisher's Exact (p<0.05). 64% female, 52% >60 years; ciprofloxacin 90%; rationality 46% (Gyssens category 0), 54% irrational (mainly short duration 44%); ATC/DDD: ciprofloxacin 47.2%, ceftriaxone 52.8%; outcome improved 94%; p=0.090 (not significant). Rationale was low, especially for duration, with no significant association with outcome; stewardship is recommended to prevent resistance.
Co-Authors Kharisma Jayak Pratama Niken Luthfiyanti