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All Journal International Journal of Health, Engineering and Technology
Mei Vita Rachma Pertiwi
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Evaluation Of The Antioxidant Activity Of Lotion Containing Ethanolic Extract Of Matoa Leaves (Pometia Pinnata J.R.Forst, & G.Forst.) Mei Vita Rachma Pertiwi; Anna Fitriawati; Annie Rahmatillah
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.672

Abstract

Skin exposure to environmental stress produces free radicals and ROS that accelerate aging and skin damage, while antioxidant Lotions from natural extracts such as Matoa leaves (Pometia pinnata) offer protection. This experimental study aimed to evaluate the antioxidant activity of ethanol extracts, the effect of concentration (0.5-6%) on the physical quality of Lotions, and the DPPH scavenging ability of the final Lotion. The population of all Matoa leaf extract Lotion formulations; a sample of 2 kg of fresh leaves from Matesih, Karanganyar was purposively selected. Instruments included a UV-Vis spectrophotometer (517 nm), a Brookfield viscometer, a pH meter; SPSS 28.0 was analyzed by ANOVA, regression for IC50. The extract was very potent (IC50 43.07 ppm) containing flavonoids, alkaloids, saponins, tannins; All Lotions met the standards (homogeneous, pH 5.22-6.34, viscosity 10,100-12,740 cP, spreadability 5-6.5 cm), FV (6%) was optimal (IC50 66.30 ppm, strong). High concentrations increased inhibition but increased viscosity, decreased spreadability (p<0.05). The findings confirm that Matoa Lotion is effective for herbal skin care; further in vivo and stability testing is recommended.
Co-Authors Anna Fitriawati Rahmatillah, Annie