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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology Kwaghe International Journal of Arts, Humanities and Religious Studies African Journal of Clinical Medicine and Pharmacy Research African Journal of Medicine, Surgery and Public Health Research
Hind A. Abdulghafoor
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Major Depressive Disorder (MDD): A Multifactorial Mental Health Crisis and Approaches to Holistic Management Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5670

Abstract

MDD, also known as Major Depressive Disorder, or clinical depression, is one of the most common and debilitating mental illnesses worldwide since it affects a person’s emotional, cognitive, and physiological functioning balance. Sufferers typically experience unrelenting low mood, anhedonia or lack of interest in activities, extreme tiredness, and numerous loopy mental and physical symptoms that negatively affect normal functioning. It’s worth emphasizing that a complex disorder, not solely an emotional state, depression arises as a result of the interplay of genetics, predisposition to the illness, neurobiological underpinnings, psychosocial and environmental stressors, as well as their myriad factors. This paper analyzes the causes, symptoms, diagnostic guidelines, and the most recent methods of treatment available for MDD. Special focus is given to psychotherapy, pharmacologic approaches, lifestyle changes, and the necessity for a holistic approach that integrates all dimensions of patient care.
Modern Microbiology: Exploring Microbial Frontiers in Health, Environment, and Biotechnology Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; , Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5818

Abstract

Microbiology, the study of microscopic organisms including bacteria, viruses, fungi, archaea, and protozoa, remains one of the most dynamic and transformative disciplines in modern science. It is foundational to understanding diverse biological systems, from molecular genetics to ecosystem function, and is integral to advancements in biotechnology, medicine, and environmental science. The field has expanded significantly with the advent of molecular biology and omics technologies, enabling precise exploration of microbial genetics, physiology, and metabolic networks. Microorganisms, while recognized as agents of disease, are also vital for global biogeochemical cycles, nutrient turnover, and ecological resilience. Recent decades have seen a surge in interest driven by the emergence of antibiotic resistance, the global burden of infectious diseases, and the need to decode host microbe interactions. Innovations such as next generation sequencing, metagenomics, and single cell analysis have redefined microbial ecology by revealing the complexity and ubiquity of unculturable microbial communities across environments—from the human gut microbiota to extreme ecosystems like deep sea hydrothermal vents. Simultaneously, the rise of synthetic biology and microbial bioengineering has paved the way for novel applications in sustainable energy, environmental remediation, and industrial biotechnology. Particularly, the human microbiome has emerged as a frontier linking microbial diversity to immunity, metabolic health, and neurodevelopmental outcomes. As microbiology increasingly converges with computational biology, nanotechnology, and systems medicine, it is poised to offer transformative solutions to global challenges in health, food security, and environmental sustainability. This overview synthesizes the current landscape of microbiological research, spotlighting core concepts and emerging directions that define the field’s evolution.
The Effects of Sleep Deprivation on Mental and Physical Health Muhammad Akram; Isaac John Umaru; Nosheen Aslam; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Abid Rashid; Jehan Mohammed Al-Musawi; Abid Mahmood
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.6248

Abstract

Sleep is a complex, restorative, and multi-stage process essential for maintaining physical health, emotional regulation, and cognitive functioning. Beyond mere rest, sleep supports vital biological functions that sustain overall well-being. However, in today’s fast-paced society, social interactions, work demands, and excessive screen time frequently take precedence over adequate sleep, leading to widespread sleep deficiency. This phenomenon, commonly referred to as sleep deprivation, is increasingly prevalent, particularly in developing countries where technological advancement, occupational pressures, and lifestyle factors disrupt natural sleep-wake cycles. This article examines the causes and consequences of insufficient sleep, exploring the underlying biological mechanisms and their impact on cardiovascular health, immune system function, mental health, memory, and quality of life. Additionally, it underscores the importance of proper sleep hygiene and presents strategies to improve sleep patterns across all age groups, aiming to mitigate the adverse effects of sleep loss and promote holistic health.
The Effect of Social Media on Mental Wellbeing: The Good and the Bad Muhammad Akram; Isaac John Umaru; Nosheen Aslam; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi; Abid Mahmood
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 2 No 2 (2025): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v2i2.6246

Abstract

Social media has evolved into a central platform for interpersonal communication and a powerful source of information within contemporary culture. While earlier generations were less accustomed to integrating technology and social media into daily life, current users actively embrace these platforms. Beyond facilitating social connections and networking opportunities, social media also serves as a tool for raising awareness and promoting various causes. However, these benefits are counterbalanced by potential negative effects on users’ emotional well-being. This paper critically examines the impact of social media on mental health, focusing on issues such as social media addiction, anxiety, depression, and self-esteem. It explores how excessive media use and social comparison contribute to psychological distress, highlighting the importance of user responsibility. Ultimately, the discussion advocates for a balanced approach to social media engagement that safeguards mental health while leveraging its positive potentials.
Managing Diabetes Mellitus in Chronic Kidney Disease: Approaches Muhammad Akram; Tahmina Maqbool; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Gaweł Sołowski; Isaac John Umaru
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 2 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i2.5222

Abstract

The main objective of this article is to review the medical management of the disease known as “diabetes mellitus” and its general consequences. To assess the risks and benefits of intensive glycemic control in patients with diabetic kidney disease, the search was refined using the following specific terms: “diabetic nephropathy” and “kidney disease”, as well as “diabetes management” and “antidiabetic agents” or “oral hypoglycemic agents”. A unique challenge. Due to changes in insulin production, glucose transport and metabolism, impaired renal function is associated with hyperglycemia and hypoglycemia. Management of hyperglycemia is more difficult in patients with diabetic nephropathy, which often requires a change in the treatment regimen. When changing diabetes medications and insulin regimens, healthcare teams responsible for the care of these patients must be vigilant and organized to make such changes.
Transforming Healthcare Through Telemedicine: A Post-Pandemic Perspective Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 2 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i2.5454

Abstract

The global chaos caused by COVID-19 gave birth to emerging telemedicine innovations throughout the world. Telemedicine automates the diagnosis and therapy processes as well as provides care to aid in such physically demanding tasks. In today's world, telemedicine is becoming one of the most effective methods of assisting patients directly due to its easily accessible reach and practicality. This paper concentrates on the epidemiology of telemedicine, along with the diverse services prescribed by the doctors through telecommunication, as well as the prevailing global communications and access problems.
Tuberculosis in the 21st Century: Challenges in Diagnosis, Treatment, and Global Control Muhammad Akram; Abid Mahmood; Mohammed Khudhair Hasan; Isaac John Umaru; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 2 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i2.5455

Abstract

With an estimated 10 million cases and over one million fatalities annually, TB is still one of the most significant infectious illnesses affecting worldwide public health, mostly in low- and middle-income nations. Mainly affecting the lungs (pulmonary TB), Mycobacterium tuberculosis is a slow-growing, acid-fast bacillus that causes tuberculosis. However, it may also affect other organs, such as the lymph nodes, bones, central nervous system, and genitourinary tract. Due to a number of variables, including delayed diagnosis, poor treatment adherence, the emergence of drug-resistant strains, and socioeconomic determinants including poverty, malnutrition, and HIV co-infection, tuberculosis (TB) continues to be a major cause of morbidity and death even though it is preventable and treatable. Bacterial evasion mechanisms and the host immune response interact intricately in the pathophysiology of tuberculosis. Latent tuberculosis infection (LTBI) can result from M. tuberculosis remaining dormant in macrophages for years after inhalation. Unless they are immunocompromised, only 5–10% of infected people experience active illness at some point in their lives. Serious obstacles to tuberculosis control and eradication have arisen as a result of the development of extensively drug-resistant tuberculosis (XDR-TB) and multidrug-resistant tuberculosis (MDR-TB), which have further complicated treatment procedures. Although recent developments include nucleic acid amplification tests (NAATs), such as GeneXpert, and interferon gamma release assays (IGRAs) for the identification of latent infections, the diagnosis of tuberculosis still mostly depends on sputum smear microscopy, chest X-rays, and culture techniques. The necessity for novel, shorter, and more efficient medication regimens is highlighted by the fact that drug-resistant TB necessitates lengthy and sometimes hazardous second-line treatment. The BCG vaccine, early case diagnosis and treatment, and public health initiatives aimed at high-risk groups are the main components of prevention programs. Because of ongoing inequalities in health care, delayed diagnosis, and poor access to and adherence to treatment, tuberculosis eradication is still a long way off, despite international efforts through programs like the WHO's End TB Strategy.
Ebola Virus Disease: A Deadly Hemorrhagic Fever Muhammad Akram; Abid Mahmood; Isaac John Umaru; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali
African Journal of Clinical Medicine and Pharmacy Research Vol 2 No 2 (2025): African Journal of Clinical Medicine and Pharmacy Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajcmpr.v2i2.5481

Abstract

The West African pandemic of 2014–2016 exposed the catastrophic effects of inadequate health systems and delayed responses, serving as a wake-up call for the international community. The Zaire virus is the most virulent of the six known Ebolavirus types and has caused the majority of human outbreaks, including the historic West African epidemic that lasted from 2014 to 2016. Depending on the virus type, host characteristics, and the availability of palliative care, Ebola can have high case fatality rates of over 50%. The potential for quick transmission, high mortality, and severe social and economic disruptions makes EVD a serious public health concern. It is believed that the Ebola virus starts in a zoonotic reservoir, most likely animals. Once in the human population, the virus is disseminated via direct contact with contaminated fomites and people. If proper infection prevention and control procedures are not implemented, family members, caregivers, and healthcare personnel are especially vulnerable. EVD manifests as a generic febrile disease that includes abrupt onset of fever, tiredness, headache, sore throat, and muscular discomfort after This is frequently followed by rash, diarrhea, vomiting, and worsening renal and liver function. Viral RNA can be found using RT-PCR, antigen capture assays, or virus isolation from blood or other clinical specimens to confirm the diagnosis. Early case identification and isolation, contact tracking, and quarantining exposed persons are essential for outbreak containment because of its high contagiousness and quick spread. The main goals of supportive treatment are electrolyte balance, fluid replenishment, and problem-solving. With the discovery of vaccinations, EVD prevention has greatly improved. Due to its excellent effectiveness, the rVSV-ZEBOV vaccine (Ervebo), a recombinant live attenuated vaccine based on the vesicular stomatitis virus, is being utilized in ring vaccination techniques during epidemics. One of the main pillars of responses to recent outbreaks is the vaccination of frontline staff and high-risk contacts.
Restoring, Repairing, and Regenerating Tissues through Biomaterials, Cells, Scaffolds, and Innovative Technologies Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5578

Abstract

Tissue engineering and regenerative medicine (TERM) is an innovative area of research and development that includes biomaterials, cells, scaffolds, scaffolding structures, and even bioactive substances to restore, repair or regenerate damaged tissues along with organs. The scope of synthetic skin expansion has now progressed to engineering kidneys, hearts, and lungs. Use of stem cell therapies or extracellular matrices for organ healing and regeneration are other; notable shifts toward tissue engineering paradigm are towards healing adn regeneration rather than the development of reconstructive surgery. While research has shown promise, there are still concerns regarding its clinical use citing complications such as immune system rejection of newly implanted tissues, ethical issues and the economical creation of engineered tissues. The efforts being made in Asia demonstrate emerging potential in TERM. Enhanced collaboration across disciplines is essential to pave new ways towards realizing current restrictions and bold influencing ideas alongside breakthroughs.
Understanding Gastritis: Causes, Symptoms, Diagnosis, and Management Muhammad Akram; Abid Mahmood; Isaac John Umaru; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammad Al-Musawi
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5580

Abstract

One such common disorder is gastritis, that is bound to cause acute or chronic inflammation of the stomach lining. It is primarily caused due to the long duration use of NSAIDs, Helicobacter pylori infection or many other reasons. Alcohol consumption, stress, bile reflux and some immunological processes also play a role in causing gastritis. While some relatives remain asymptomatic, most relatives experience symptoms such as epigastric discomfort, vomiting, and, in some cases, gastrointestinal bleeding. H. Pylori detection, endoscopic examination, and histopathology are the primary techniques for diagnosing gastritis. Another method of treatment is the use of proton pump inhibitors along with lifestyle changes, or antibiotics. Gastritis and its symptoms can be mitigated by employing primary prevention strategies like proactively treating H. Pylori infections or reducing NSAIDs consumption.
Co-Authors , Jaouher Ben Ali Abid Mahmood Abid Rashid Fahad Said Khan Fethi Ahmet Ozdemi Fethi Ahmet Ozdemir Gaweł Sołowski Isaac John Umaru Jaouher Ben Ali Jehan Mohammad Al-Musawi Jehan Mohammed Al-Musawi Jehan Mohammed Jehan Mohammed Al-Musawi Mohammed Khudhair Hasan Muhammad Akram Nosheen Aslam Tahmina Maqbool