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All Journal African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology Kwaghe International Journal of Arts, Humanities and Religious Studies African Journal of Clinical Medicine and Pharmacy Research African Journal of Medicine, Surgery and Public Health Research
Jaouher Ben Ali
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Emerging Applications and Challenges of Nanotechnology in Medicine and Nutrition Muhammad Akram; Abid Mahmood; Mohammed Khudhair Hasan; Isaac John Umaru; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5484

Abstract

Emerging applications of nanotechnology in medicine and nutrition present both significant opportunities and challenges that warrant thorough investigation. This study aims to explore the intersection of nanotechnology and genomic nutrition, focusing on how these advancements can enhance preventive care and health outcomes. Employing a qualitative descriptive methodology, we conducted a comparative analysis of existing literature and case studies to assess the implications of these technologies on dietary customization and patient-provider relationships. Our findings reveal that nanotechnology facilitates the development of targeted nutritional interventions that align with individual genetic profiles, thereby improving adherence to dietary guidelines and mitigating disease risk. Furthermore, we identify that the integration of continuous health monitoring technologies fosters a collaborative partnership between patients and healthcare providers, enhancing communication and decision-making processes in treatment and preventive initiatives. The implications of this research underscore the necessity for healthcare systems to adopt technological advancements to address the complexities of modern medicine effectively. By embracing these innovations, the potential for precision medicine is significantly amplified, paving the way for improved health outcomes and personalized nutrition strategies in the future.
Evolution of DNA Technology in Treating Animal Diseases Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammad Al-Musawi
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5582

Abstract

A single gene mutation can result in aberrant cell activity and the production of a faulty protein. The cell will certainly operate very poorly or not at all as a result of this mutation. Given that the genetic material may be a therapeutic agent; this might be seen as qualitatively distinct from other conventional drugs. Gene therapy may be able to rectify or perhaps cure the pathophysiology of a disease by changing the genetic composition of cells. In veterinary medicine, genetic engineering has been used to xenografts, and detects, prevent, and treat illnesses. Among the challenges that gene therapy faces include transfection, intracellular vector stability, cellular and nuclear entrance, and ethical concerns. Deficits in gene transfer vectors and a lack of knowledge about the biological interactions between these vectors and the host are two examples of fundamental challenges.
Microbial Genetics: Foundations, Applications, and Future Directions in Science and Biotechnology Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammad Al-Musawi
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5652

Abstract

This field is essential to comprehending not just basic biological processes but also how they are used in biotechnology, agriculture, and medicine. Microbial genetics is the study of genetic material, which includes horizontal gene transfer, DNA replication, gene expression, and mutation. Many microorganisms, in contrast to larger species, have genomes that are small and relatively basic, enabling researchers to accurately examine the regulation and function of genes. Mechanisms like transformation, transduction, and conjugation, which speed up the acquisition and spread of genetic characteristics like antibiotic resistance, are primarily responsible for the genetic plasticity of microorganisms, especially bacteria. Given that existing treatment approaches are being challenged by the growth consequences. Additionally, using cutting-edge molecular methods like whole-genome sequencing, recombinant DNA technology, and CRISPR-Cas systems, microbial genetics aids in the creation of novel antibiotics, vaccines, and diagnostic instruments. The intricacies of microbial communities, or microbiomes, and their interactions with hosts and the environment have also been clarified by research in microbial genetics. Our knowledge of microbial ecology, pathogenicity, and symbiosis has increased as a result. The discipline is still developing in industrial settings, but the combination of systems genetics and computational biology holds promise for deciphering intricate regulatory networks and enabling predictive modeling of microbial behavior. As microbial genetics advances, ethical issues—especially those pertaining to gene editing and the discharge of genetically engineered organisms—become more significant. To sum up, microbial genetics is a fundamental component of contemporary biology and biotechnology, offering deep understanding of microbial life and laying the groundwork for advancement in a wide range of scientific and industrial domains. Addressing global health, sustainability, and environmental management concerns requires ongoing study in this area.
Cell Dynamics: Mechanisms, Technologies, and Applications in Health and Disease Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammad Al-Musawi
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.5653

Abstract

The intricate and well-coordinated activities of cells in response to both internal and external stimuli are referred to as cell dynamics. These behaviors help living things grow, differentiate, maintain, and adapt. Using a variety of interdisciplinary techniques from molecular biology, biophysics, computational modeling, and live-cell imaging, this field examines the dynamic processes that control cell morphology, intracellular transport, cytoskeletal reorganization, signal transduction, and cell motility. The capacity of cells to alter their structure and function in real time, allowing for quick reactions to changes in the environment, damage, or developmental signals, is a key component of cell dynamics. The complex coordination of cytoskeletal filaments, vesicle trafficking channels, and signaling networks that underpin activities including mitosis, migration, immunological surveillance, and synaptic plasticity has been made visible by developments in high-resolution imaging and single-cell analysis. Recent research has demonstrated that cellular activities incorporate stochastic fluctuations, spatial compartmentalization, and emergent features resulting from the combined actions of molecular complexes, in addition to deterministic biochemical routes. It has been demonstrated that the mechanical characteristics of the cellular microenvironment, such as the extracellular matrix composition and substrate stiffness, are essential for regulating dynamic cellular responses, especially during wound healing, tissue formation, and cancer progression. Additionally, the enormous datasets produced by live-cell imaging and omics technologies are being decoded more and more using computational models and artificial intelligence tools, which offer fresh perspectives on the temporal and spatial control of cellular activities. In addition to expanding our understanding of basic cell biology, an understanding of cellular dynamics may help develop therapeutic approaches that target dysregulated cellular activities in conditions including cancer, dementia, and immunological disorders. In order to anticipate cellular outcomes and manipulate cell destiny for applications in synthetic biology and regenerative medicine, it will be crucial to combine quantitative modeling with experimental data as we continue to clarify the fundamentals of cellular structure and adaptability.
Cloning in Plants and Animals: Divergent Pathways and Ethical Boundaries in Biotechnology Muhammad Akram; Isaac John Umaru; Nosheen Aslam; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi; Abid Mahmood
African Journal of Biochemistry and Molecular Biology Research Vol 2 No 2 (2025): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v2i2.6140

Abstract

The creation of genetically identical creatures by cloning is essential to contemporary biotechnology, agriculture, and medical research. Although the basic idea of cloning is the same in all kingdoms, there are substantial differences between plants and animals in terms of its use, effectiveness, and moral consequences. Cloning is a common, natural occurrence in plants and is frequently accomplished using asexual reproduction procedures such as tissue culture, grafting, and vegetative propagation. Because plant cells are highly totipotent, practically any somatic cell may grow again into a whole organism given the right circumstances. The production of genetically engineered plants with enhanced features, the preservation of uncommon species, and the large-scale multiplication of genetically uniform crops have all been made easier by this regenerative potential. Animal cloning, on the other hand, poses far more biological and technological difficulties. Due to developmental errors, aberrant gene expression, and insufficient reprogramming of the donor nucleus, this procedure usually has poor success rates and necessitates intricate management. It brings up important issues about biodiversity, animal care, and the ethical ramifications of cloning sentient creatures. Furthermore, animal cloning is more closely regulated and scrutinized by the public than plant cloning, which is generally recognized in agricultural operations and conservation initiatives. This is particularly true when it comes to food production and possible human cloning. The difference in the effectiveness and uses of cloning is mostly explained by the difference in totipotency between plant and animal cells. The accuracy of modification is becoming closer thanks to recent technological advancements like CRISPR-Cas9, yet the ethical and practical possibilities of cloning in these two domains are still not comparable. The intricate relationship between biological viability, technical development, and societal acceptability of interspecies cloning is shown by this comparative study. Guidance on the proper application and control of cloning technologies in biomedicine and agriculture depends on an understanding of these distinctions.
Peptic Ulcer Disease: A Comprehensive Review of Etiology, Diagnosis, and Modern Therapeutic Approaches Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5640

Abstract

Peptic ulcer disease (PUD) is an ailment of the gastrointestinal tract that is quite common and is marked by the development of open lesions known as ulcers in the stomach as well as in the proximal duodenum. It arises as a consequence of the imbalance between the protective enzymatic mechanisms of the mucosa, and the injurious agents like gastric acid, pepsin, Helicobacter pylori, and even non-steroidal anti-inflammatory drugs (NSAIDs). While many ulcers heal spontaneously, complications such as bleeding, perforation, and gastric outlet obstruction can lead to serious morbidity or mortality. With PUD, they can be treated and/or prevented if basic instruction is provided alongside a proper overview of the condition's etiological basis. In this case, pharmacological therapy and endoscopic procedures are heavily applicable.
IBS: Pathophysiology and Management Challenges Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Jehan Mohammed Al-Musawi
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5641

Abstract

Irritable Bowel Syndrome (IBS) is a widespread functional gastrointestinal ailment with chronic abdominal pain, change in bowel movements, and reduced quality of life as hallmarks. Unlike organic diseases, IBS is idiopathic—diagnosed in the absence of structural or biochemical disturbances, which makes disease management more difficult. The causes of IBS are heterogeneous: dysregulation of gut-brain axis, visceral hypersensitivity, motility disorders, changes in microbiome, and psychosocial aspects contribute to it. This article explains causes of IBS, symptomatology, diagnostic criteria, and treatment options multidisciplinary with a focus on tailored dietary intervention, medication, psychotherapy, as well as alternative methods.
Preserving Biodiversity: The Vital Role of Flora and Fauna in Global Sustainability Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemi; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
African Journal of Sciences and Traditional Medicine Vol 2 No 2 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i2.5814

Abstract

The ecological balance of the planet, human well-being, and the vitality of natural systems are inextricably linked to the diversity of flora and fauna—biological resources that sustain life through myriad ecosystem services. Flora, comprising the world’s plant life, is fundamental to oxygen production, carbon sequestration, and photosynthetic energy transfer, forming the base of nearly all food webs. Fauna, encompassing animal life, plays critical roles in pollination, seed dispersal, pest regulation, and nutrient cycling. The vast biodiversity encapsulated in global flora and fauna represents the outcome of millions of years of evolution and adaptation. However, unprecedented anthropogenic pressures—including deforestation, habitat destruction, pollution, climate change, overexploitation, and biological invasions—have precipitated significant biodiversity loss in the twenty-first century. This decline jeopardizes not only ecological stability but also the essential services that underpin human health, agriculture, and economic development. In response, disciplines such as environmental science, conservation biology, and sustainable development have mobilized to advocate for the protection of biodiversity through international frameworks like the Convention on Biological Diversity (CBD), targeted species and habitat conservation programs, and enhanced biodiversity monitoring systems. This paper underscores both the intrinsic and utilitarian value of biodiversity, highlighting the urgent need for coordinated global action. Ensuring the persistence of biological diversity demands reinforced environmental governance, expanded protected area networks, ecological restoration, and the integration of sustainability principles into development agendas. The survival of flora and fauna is not only an environmental imperative but a foundation for human resilience and planetary sustainability.
Generalized Anxiety Disorder (GAD): Understanding Its Roots, Impact, and Modern Approaches to Treatment Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5668

Abstract

Chronic worry and anxiety about particular areas of functioning or life shifts Characterizes GAD. Generalized anxiety disorder GAD remains one among the most widespread and enduring forms of anxiety disorder. GAD doesn’t arise out of thin air, but is often associated with deeper, systematic issues at hand. Not only does GAD affect one neurologically, but it impacts their emotional, social, and occupational functionality. Globally, millions face GAD. Furthermore, unlike anxiety regarding day-to-day things, GAD has no identifiable ‘weakness’ that triggers it, making it chronic in nature and extremely hard to control without professional support. In this article, I will aims towards incorporating the important aspects of GAD exploring its headline causes, diagnostic rules, prominent face, and fusion of treatment including modern medicine alongside proactive methods like exercise, psychotherapy, and self-help programs. Primarily focus is laid on CBT alongside mindfulness approaches, innovation due to neurobiology in treatment, and neurobiology’s impact on understanding and eradicating illness.
Major Depressive Disorder (MDD): A Multifactorial Mental Health Crisis and Approaches to Holistic Management Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5670

Abstract

MDD, also known as Major Depressive Disorder, or clinical depression, is one of the most common and debilitating mental illnesses worldwide since it affects a person’s emotional, cognitive, and physiological functioning balance. Sufferers typically experience unrelenting low mood, anhedonia or lack of interest in activities, extreme tiredness, and numerous loopy mental and physical symptoms that negatively affect normal functioning. It’s worth emphasizing that a complex disorder, not solely an emotional state, depression arises as a result of the interplay of genetics, predisposition to the illness, neurobiological underpinnings, psychosocial and environmental stressors, as well as their myriad factors. This paper analyzes the causes, symptoms, diagnostic guidelines, and the most recent methods of treatment available for MDD. Special focus is given to psychotherapy, pharmacologic approaches, lifestyle changes, and the necessity for a holistic approach that integrates all dimensions of patient care.
Co-Authors Abid Mahmood Fahad Said Khan Fethi Ahmet Ozdemi Fethi Ahmet Ozdemir Gaweł Sołowski Hind A. Abdulghafoor Isaac John Umaru Jehan Mohammad Al-Musawi Jehan Mohammed Al-Musawi Jehan Mohammed Jehan Mohammed Al-Musawi Mohammed Khudhair Hasan Muhammad Akram Nosheen Aslam