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All Journal MEDULA Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo
Amiruddin Eso
Halu Oleo University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Relationship Between Food Consumption Patterns and Nutritional Status in Nambo Sub-District Community Aisyah Az-Zahrah Mansur; Nina Indriyani Nasruddin; Amiruddin Eso
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 2 (2023): April
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

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Abstract

Background: Nutritional status is an individual's health condition, which is determined by the degree of physical need for energy and nutrients obtained from food. The most important behavior that can affect nutritional status is consumption pattern. This is because the quantity and quality of consumed food and drink will affect nutritional intake, which in turn it will affect the health of individuals and society. Purposes: The purpose of this study is to determine the relationship between consumption patterns of carbohydrate source foods and nutritional status in the people of Nambo District. Method: This research is an observational analytic study with a cross sectional approach. This study's population includes all residents of the Nambo District. The research sample consisted of 106 respondents, who were selected using the purposive sampling technique. Data collection included examining nutritional status by weighing and measuring height as well as conducting interviews using Food Recall 24 Hours for 2 days. Data were analyzed by Spearman's rank test. Results: The results of this study indicate that there is a significant relationship (p < 0.05) between the consumption patterns of carbohydrate source foods and nutritional status in the people of Nambo District, and the value of r = 0.493 indicates the strength of the correlation between consumption patterns of carbohydrate source foods and nutritional status in the people of Nambo District is moderate in nature with a positive correlation direction, which indicates a unidirectional correlation direction. Conclusion: There is a relationship between consumption patterns of carbohydrate source foods and nutritional status among the people of Nambo District.
The Impact of the Ethyl Acetate Fraction of Bitter Melon Fruit (Momordica charantia l.) on Insulin Hormone Levels of Diabetic Rats (Rattus norvegicus) Using the Enzyme-Linked Immunosorbent Assay Method Parawansah; Tien; Amiruddin Eso; Muhammad Junaid Azis; Nuralifah
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

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Background: The World Health Organization (WHO) has forecast a rise in the prevalence of diabetes mellitus from 2.8% in 2000 to 4.4% in 2030. Numerous investigations have been undertaken to identify alternate avenues for antidiabetic treatment. Momordica charantia, sometimes referred to as bitter melon, is recognized for its possession of mimic insulin components. The ethanol extracts derived from Momordica charantia have been found to exhibit favorable outcomes in the reduction of blood glucose levels and the stimulation of pancreatic beta cells for the secretion of insulin hormone. Purpose: The purpose of this research is to investigate the impact of bitter melon extract on insulin levels in rats induced with streptozotosin. Method: The present study employed various methodologies to investigate the research question. The present investigation comprised three distinct sets of tests, specifically streptozotosin-induced rats, streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract, and non-induced streptozotosin rats. The measurement of insulin levels is conducted using the enzyme-linked immunosorbent assay (ELISA) technique. If the p-value was more than 0.05, an unpaired T-test was employed for data analysis. Result: The research findings indicate that there is no statistically significant distinction in the insulin levels between streptozotosin-induced rats and streptozotosin-induced rats administered with the ethyl acetate fraction of the Momordica charantia extract group (p = 0.081). The insulin levels of streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract were found to be statistically similar to those of non-induced streptozotosin rats (p = 0.505). Conclusion: There is no discernible distinction in the insulin levels among streptozotosin-induced rats, streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract, and non-induced streptozotosin rats.
The Effect Of Isometric Handgrip Exercise In Reducing Blood Pressure Of Hypertension Patients In Bajoe Village, Soropia Subdistrict, Konawe Regency Wikal Sulistia Dwi Putra; Amiruddin Eso; Pranita Aritrina Syafri; Yenti Purnamasari
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 2 (2024)
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v11i2.35

Abstract

ABSTRACT Background. Hypertension is a condition where systolic blood pressure is ≥140 mmHg and diastolic pressure is ≥90 mmHg at rest. Isometric handgrip exercise is one type of exercise that is effective in reducing blood pressure in patients with hypertension. The purpose of this study was to determine the effect of isometric handgrip exercise in reducing blood pressure in hypertensive patients in Bajoe Village, Soropia Subdistrict, Konawe Regency. Methods. This study used a pre-experiment research design with a one group pretest posttest design approach with the independent variable being isometric handgrip exercise and the dependent variable being blood pressure. The sample in the study was the community of Bajoe Village, Soropia Subdistrict, Konawe Regency who suffered from hypertension as many as 30 people who were taken using Purposive Sampling technique and data analysis using Paired sample t test. Data obtained from blood pressure measurements measured before and after doing isometric handgrip exercise for 5 minutes in 5 consecutive days. Results. The results obtained from 30 samples showed that isometric handgrip exercise intervention reduced mean systolic blood pressure by 7.35 mmHg (p = 0.000) and mean diastolic blood pressure by 2.53 mmHg (p = 0.000). Conclusion. There is an effect of isometric handgrip exercise in reducing blood pressure of hypertensive patients in Bajoe Village, Soropia Subdistrict, Konawe Regency.
The Antibacterial Activity of Arabian Bidara Leave (Ziziphus spina-christi L.) against the growth of Escherichia coli Sufiah Asri Mulyawati; Amiruddin Eso; Yusni Nurul Hidayah
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 2 (2024)
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v11i2.38

Abstract

ABSTRACT Background: The primary cause of mortality for children, according to the World Health Organization, is infectious illnesses. Escherichia coli is one of the bacteria that may infect people. Infections caused by E. coli have historically been treated with antibiotics. Antibiotic resistance, however, can result from improper usage. Arabian Bidara is a plant that has been shown to possess antibacterial qualities, making it a viable alternative therapy. The antibacterial properties of this plant's leaves effectively combat a variety of dangerous germs and pathogens. Purposes: to determine the effectiveness of the ethanolic extract of bidara arabic leaves as an antibacterial against the growth of Escherichia coli bacteria. Methods: This research are an experimental study with a post test only control group design with the independent variable being the treatment of arabic bidara leaf extract, the dependent variable being the zone of inhibition against Escherichia coli . Positive control in the form of ciprofloxacin and negative control using distilled water. The concentrations used were 1500 ppm, 2000 ppm, 2500 ppm and 3000 ppm with three repetitions. Results: This study showed that the ethanolic extract of bidara arabic leaves could inhibit the growth of Escherichia coli bacteria with a strong zone of inhibition at concentrations of 2000 ppm, 2500 ppm, and 3000 ppm and an inhibition zone category classified as weak at a concentration of 1500 ppm. Conclusion: There is antibacterial effectiveness of the ethanolic extract of the leaves of the arabic bidara (Ziziphus spina-christi L.) against the growth of Escherichia coli bacteria. Keywords: Antibacterial; Escherichia coli ; Ziziphus spina-christi L
Effectivity Test of Ethanol Extract of Arabic Bidara Leaf (Ziziphus Spina-Christi L.) As Antibacterially Against Growt Bacteria Pseudomonas aeruginosa and Bacillus cereus Vira Adiningsi; Amiruddin Eso; Yenti Purnamasari
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 2 (2024)
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v11i2.40

Abstract

Background. Infection disease is one of the major health problems in developing countries including Indonesia, one of which is nosocomial infection caused by Pseudomonas aeruginosa bacteria. On the other hand, food poisoning is still a serious problem in Indonesia especially caused by pathogenic bacteria, one of which is Bacillus cereus bacteria. Indonesia is famous for its potential as home to medicinal plants. One plant that can potentially be used as an alternative in the treatment of this bacterial infection is arabic bidara leaves. This study aims to find out the effectiveness of arabic bidara leaf ethanol extract (Ziziphus spina-christi L.) as antibacterial against bacterial growth of Pseudomonas aeruginosa and Bacillus cereus. Methods. This study was an experimental study with a post test only control group design with a free variable in the form of treatment of arabic bidara leaf extract, a bound variable in the form of an inhibitory zone against Pseudomonas aeruginosa and Bacillus cereus. Positive control of ciprofloxacin and negative control using aquades. The concentrations used were 1500 ppm, 2000 ppm, 2500 ppm and 3000 ppm with three repetitions. Results. An ethanol extract of arabic bidara leaves has an inhibitory zone classified as strong at concentrations of 2000 ppm, 2500 ppm, and 3000 ppm. Conclusion. There is an antibacterial effectiveness of arabic bidara leaf ethanol extract against bacterial growth of Pseudomonas aeruginosa and Bacillus cereus. Keywords: Antibacterial, Bidara Arab Leaves, Pseudomonas aeruginosa, Bacillus cereus
Difference in Intraocular Pressure Before and After Cataract Surgery with Glaucoma Complications at Kendari Eye Clinic Amiruddin Eso; Deni Sastra Mandarin; Melvin Manuel Philips
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

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Abstract

Background: Cataracts and glaucoma are the leading causes of irreversible blindness worldwide and frequently coexist in elderly populations. Cataract-induced structural changes in the anterior segment may impair aqueous humor outflow, resulting in elevated intraocular pressure (IOP) and accelerated optic nerve damage in patients with glaucoma. Purpose(s): This study aimed to analyze differences in IOP before and after cataract surgery among patients with glaucoma complications at Kendari Eye Clinic. Methods: An observational analytic study with a pre–post cross-sectional design was conducted using medical record data from January to June 2024. A total of 100 patients with senile cataracts complicated by glaucoma who underwent phacoemulsification were included using purposive sampling. IOP measurements were obtained using a non-contact tonometer before surgery and at 3 days, 5 days, 12 days, and 1 month postoperatively. Data were analyzed using the Friedman test. Results: The results demonstrated a statistically significant difference in IOP before and after surgery (p < 0.001). Mean IOP increased transiently at 3 days postoperatively but decreased significantly at subsequent follow-up intervals. Conclusion: Phacoemulsification cataract surgery significantly reduces IOP in patients with glaucoma complications, emphasizing its role not only in visual rehabilitation but also in IOP control and glaucoma management.
Co-Authors Aisyah Az-Zahrah Mansur Deni Sastra Mandarin Melvin Manuel Philips Muhammad Junaid Azis Nina Indriyani Nasruddin Nuralifah Parawansah Pranita Aritrina Syafri Sufiah Asri Mulyawati Tien Vira Adiningsi Wikal Sulistia Dwi Putra Yenti Purnamasari Yusni Nurul Hidayah