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All Journal Manuju : Malahayati Nursing Journal JURNAL ANALIS LABORATORIUM MEDIK Jurnal Ilmiah Manusia dan Kesehatan TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Jurnal Ilmiah Kesehatan Masyarakat Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Farida Noor Irfani
Universitas ‘Aisyiyah Yogyakarta
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Gambaran Pemeriksaan Imunologi terhadap Pasien Tirotoksikosis di Rumah Sakit PKU Muhammadiyah Yogyakarta Periode 2020 – 2025 Muthi’ah Fadhilah Aliffani; Farida Noor Irfani; Dhiah Novalina
Malahayati Nursing Journal Vol 7, No 12 (2025): Volume 7 Nomor 12 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i12.23494

Abstract

ABSTRACT Thyroid disorders are one of the most common endocrine health problems after diabetes and affect the body's metabolism and hormonal function. This study aims to describe the immunological examination results of Thyroid Stimulating Hormone (TSH) and Free Thyroxine (FT4) levels in patients with thyrotoxicosis- type thyroid disorders atPKU Muhammadiyah Hospital, Yogyakarta, from 2020– 2025. The study employed a descriptive method with a cross-sectional approach based on secondary data from medical records and laboratories. The study sample consisted of 34 thyrotoxicosis patients selected using consecutive sampling. Data analysis was performed using univariate and bivariate methods using Spearman's correlation test. The results showed that the majority of patients were female(82.4%), with the majority aged 30–59 years (70.6%). Most patients had low TSH levels (58.8%), and all patients hadhigh FT4 levels (100%). The correlation test showed no significant association between age or gender and TSH and FT4 levels (p0.05). This study concluded that the majority of thyrotoxicosis patients were women of reproductive age,with low TSH and high FT4 levels, without any significant association with age or gender. Keywords: Thyroid disorders, Thyrotoxicosis, TSH, FT4, Imunology  ABSTRAK Gangguan tiroid merupakan salah satu masalah kesehatan endokrin terbanyak setelah diabetes dan memengaruhi metabolisme serta fungsi hormonal tubuh. Penelitian ini bertujuan untuk mengetahui gambaran hasil pemeriksaan imunologi kadar Thyroid Stimulating Hormone (TSH) dan Free Thyroxine (FT4) pada pasien gangguan tiroid jenis tirotoksikosis di RS PKU Muhammadiyah Yogyakarta periode 2020–2025. Penelitian menggunakan metode deskriptif dengan pendekatan cross-sectional berdasarkan data sekunder dari rekam medis dan laboratorium. Sampel penelitian sebanyak 34 pasien tirotoksikosis yang dipilih dengan metode consecutive sampling. Analisis data dilakukan secara univariat dan bivariat menggunakan uji korelasi Spearman’s. Hasil penelitian menunjukkan bahwa sebagian besarpasien berjenis kelamin perempuan (82,4%) dengan usia terbanyak 30–59 tahun (70,6%). Sebagian besar pasien memilikikadar. TSH rendah (58,8%) dan seluruh pasien memiliki kadar FT4 tinggi (100%). Uji korelasi menunjukkan tidak terdapat hubungan signifikan antara usia maupun jenis kelamin dengan kadar TSH dan FT4 (p0,05). Penelitian ini menyimpulkan bahwa mayoritas pasien tirotoksikosis adalah perempuan usia produktif dengan gambaran TSH rendah dan FT4 tinggi tanpa adanya hubungan bermakna dengan faktor usia dan jenis kelamin. Kata Kunci: Gangguan Tiroid, Tirotoksikosis, TSH, FT4, Imunologi
Gambaran Infertilitas Pada Wanita Berdasarkan Status Follicle Stimulating Hormone (FSH) dan Luteinizing Hormone (LH) Rskia Sadewa Salzabilla Poha; Farida Noor Irfani; Arif Bimantara
Malahayati Nursing Journal Vol 7, No 10 (2025): Volume 7 Nomor 10 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i10.22588

Abstract

ABSTRACT Infertility is a complex condition that can be caused by various factors, including imbalances in reproductive hormones such as Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH). To describe infertility in women based on FSH and LH hormone levels at RSKIA Sadewa. This study used a descriptive quantitative method with secondary data obtained from the medical records of infertile female patients at RSKIA Sadewa during the period of July 2024 to June 2025. Data were analyzed univariately and Chi-square using SPSS. Examinations for infertility were most commonly performed in women aged 26–35 years. Abnormal levels of FSH and LH were more frequently observed in age groups 25 years and 35 years. Chi-square test showed no significant association between age and FSH levels (p=0.371) or LH levels (p=0.377). There is no significant association between FSH and LH levels and age in infertile women. Infertility is multifactorial, influenced not only by hormonal levels but also by other factors beyond the reproductive hormonal system. Keywords: Infertility, FSH Hormone, LH Hormone, Female Reproduction  ABSTRAK Infertilitas merupakan permasalahan kompleks yang dapat disebabkan oleh berbagai faktor, termasuk ketidakseimbangan hormon reproduksi seperti Folliclestimulating Hormone (FSH) dan Luteinizing Hormone (LH).Mengetahui gambaran infertilitas pada wanita berdasarkan kadar hormon FSH dan LH di RSKIA Sadewa. Penelitian ini menggunakan metode deskriptif kuantitatif dengan data sekunder dari rekam medis pasien wanita infertil di RSKIA Sadewa periode Juli 2024–Juni 2025. Data dianalisis secara univariat dan uji Chi-square menggunakan SPSS.Pemeriksaan infertilitas paling banyak ditemukan pada wanita usia 26–35 tahun. Abnormalitas kadar FSH dan LH lebih sering terjadi pada kelompok usia 25 tahun dan 35 tahun. Uji Chi-square menunjukkan tidak ada hubungan signifikan antara usia dengan kadar FSH (p=0,371) maupun LH (p=0,377). Tidak terdapat hubungan signifikan antara kadar FSH dan LH dengan usia pada wanita infertil. Infertilitas bersifat multifaktorial, tidak hanya dipengaruhi kadar hormon, tetapi juga faktor lain di luar sistem hormonal. Kata kunci: Infertilitas, Hormon FSH, Hormon LH, Reproduksi Wanita
HUBUNGAN TEKANAN DARAH DAN KADAR GULA DARAH PASIEN DIABETES MELITUS TIPE 2 DI RSUD NYI AGENG SERANG TAHUN 2024 Wahyuni Fanlai; Arif Bimantara; Farida Noor Irfani
Jurnal Analis Laboratorium Medik Vol 11 No 1 (2026): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jalm.v11i1.5994

Abstract

Latar Belakang: Diabetes melitus tipe 2 bisa dikatakan penyakit serius yang ditandai dengan hiperglikemia akibat masalah sekresi atau fungsi insulin dan berpotensi menyebabkan komplikasi, salah satunya hipertensi atau dikenal dengan tekanan darah tinggi. Tujuan: untuk mengetahui hubungan antara jumlah glukosa darah dan tekanan darah pada pasien diabetes melitus tipe 2 di Rumah Sakit Umum Daerah Nyi Ageng Serang Yogyakarta Tahun 2024. Metode: metode kuantitatif dengan desain cross sectional. Sampel diperoleh dengan purposive sampling dan total sampel sebanyak 94 responden. Data sekunder diperoleh dari data periode tahun 2024 di Rumah Sakit Umum Daerah Nyi Ageng Serang Yogyakarta. Data penelitian dianalisis dengan metode univariat untuk karakteristik responden dan bivariat untuk hubungan antara diabetes melitus dengan hipertensi menggunakan SPSS versi 26. Hasil: menunjukkan bahwa berdasarkan usia dan jenis kelamin dari 94 total sampel pasien, paling banyak adalah pasien perempuan pada kelompok usia lanjut yaitu >65 tahun sebanyak 20 orang (21,3%). Kesimpulan: Terdapat hubungan antara hipertensi dengan tingkat glukosa darah dimana mayoritas sampel pasien memiliki kadar glukosa darah tidak terkontrol dengan tekanan darah tinggi (hipertensi) sebanyak 61 orang (64,9%). Disarankan agar rumah sakit meningkatkan pemantauan rutin kadar glukosa darah dan tekanan darah pada pasien diabetes melitus tipe 2 serta memperkuat edukasi terkait pengendalian gaya hidup. Penelitian selanjutnya dapat menambahkan variabel pola makan, aktivitas fisik, dan durasi penyakit untuk memperoleh hasil yang lebih komprehensif.
Gambaran Kadar TSH, FT3 dan FT4 pada Pasien Gangguan Tiroid di RSUD Anutaloko Parigi Khafifa Usnul Mar’iyah Dg Tompo; Nazula Rahma Shafriani; Farida Noor Irfani
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6023

Abstract

Thyroid disorders are a problematic condition in individuals due to dysfunction of the thyroid gland, such as changes in its form and function. The most common thyroid disorders include hyperthyroidism and hypothyroidism. This study aims to identify and analyze TSH, FT3, and FT4 levels in individuals diagnosed with thyroid disorders. This research uses a cross-sectional method by collecting secondary data. Secondary data for this research was obtained from records of TSH, FT3 and FT4 hormone examinations in the laboratory at Anutaloko Parigi Regional Hospital. This data covers the period January to December 2024, then processed and analyzed using descriptive statistical tests in SPSS, then presented in table format. Based on age characteristics, the majority of respondents with thyroid disorders were aged 25-59 years with a percentage of 25 people with hyperthyroidism and 11 people with hypothyroidism. Respondents with the most thyroid disorders were diagnosed with hyperthyroidism rather than hypothyroidism. The total number of patients who had TSH, FT3 and FT4 checked at Anutaloko Parigi Regional Hospital found that patients with hyperthyroidism were predominantly female and aged 25-59 years.
Pengaruh Hormon FSH Dan Testosteron Terhadap Infertilitas Laki-Laki Di RSKIA Sadewa Periode 2025 Moh.Firgiawan Dwiyanto; Farida Noor Irfani; Nazula Rahma Shafriani
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 9 No. 3 (2026): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v9i3.4555

Abstract

Infertilitas merupakan salah satu masalah kesehatan reproduksi yang masih menjadi perhatian di tingkat global maupun nasional, dengan faktor laki-laki berkontribusi terhadap sekitar 40–50% kasus infertilitas. Gangguan hormonal, khususnya yang melibatkan Follicle Stimulating Hormone (FSH) dan testosteron, berperan penting dalam proses spermatogenesis dan fungsi reproduksi pria. Penelitian ini bertujuan untuk mengetahui kadar hormon FSH dan testosteron serta hubungan antara kedua hormon tersebut pada pasien infertil laki-laki di RSKIA Sadewa Yogyakarta periode 2025. Penelitian ini menggunakan desain analitik observasional dan pendekatan cross-sectional berdasarkan data rekam medis pasien infertil laki-laki yang menjalani pemeriksaan kadar FSH dan testosteron. Sebanyak 245 pasien memenuhi kriteria penelitian. Hasil penelitian menunjukkan bahwa rata-rata kadar FSH sebesar 5,86 mIU/mL dan rata-rata kadar testosteron sebesar 5,19 ng/mL. Analisis hubungan antara kadar FSH dan testosteron menggunakan uji korelasi Spearman menunjukkan tidak terdapat hubungan yang signifikan antara kedua variabel (r = -0,030; p = 0,638). Analisis lebih lanjut juga menunjukkan bahwa usia dan lama infertilitas tidak berpengaruh secara signifikan terhadap kadar hormon FSH maupun testosteron pada pasien infertil laki-laki di RSKIA Sadewa periode 2025. Disimpulkan bahwa kadar FSH dan testosteron pada pasien infertil laki-laki memiliki distribusi yang beragam, namun tidak menunjukkan hubungan yang signifikan satu sama lain, serta tidak dipengaruhi secara bermakna oleh usia dan lama infertilitas. Temuan ini menunjukkan bahwa infertilitas pria merupakan kondisi multifaktorial yang tidak hanya dipengaruhi oleh kadar FSH dan testosteron
Analisis Hasil Pemeriksaan Viral Load Dan CD4 Pada Penderita HIV Di RSUD Pandan Arang Boyolali Periode Tahun 2022 Wirna Sari; Farida Noor Irfani
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 3 No. 3 (2024): September : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v3i1.2630

Abstract

Acquired Immunodeficiency Syndrome disease cause HIV. This disease damages the body's immune system known as CD4. CD4 lymphocyte count is associated with disease progression, increased opportunism, and mortality. Laboratory examination required to determine the CD4 count using this method flowcytometry, and test viralload PCR method. The of research is analyze results of viralload and CD4 in HIV sufferers at RSUD Boyolali . Quantitative research method with analytical descriptive design. Data univariate and bivariate with the chi-square test to see the magnitude of relationship between the independent variables and HIV infection. total of 94 patients in 2022 showed several normal and abnormal results, where values ​​were normal viralload <10,000copy/ml low, >100,000copy/ml high, and <40copy/ml not detected. Normal CD4 results 410 – 1,600 cells/ml and low <500 cells/ml. CD4 research results and viralload normal 43 (46%) patients, CD4 results and viralload abnormal in about 9 (9%), and 1% of patients with normal CD4 countsviral load abnormal patient has not received treatment. CD4 examination uses the method flowcytometry whereas viral load using the PCR method and blood plasma samples. There is relationship viralload method PCR dan CD4 method flowcytrometry with significance value of 0.013. Further research needs to be carried out using experimental methods.
Pemeriksaan Imunologi Terhadap Kadar Hormon Thyroid Stimulating Hormone (TSH) Pada Pasien Gangguan Tiroid Di RSUD Panembahan Senopati Periode 2020-2022 Rifka Aulia Astuti; Farida Noor Irfani
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 3 No. 3 (2024): September : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v3i1.2631

Abstract

Thyroid disorders are conditions of abnormalities in thyroid gland. According to function, thyroid disorders are divided into three, hyperthyroidism, hypothyroidism and euthyroidism. To detect thyroid disorders, can use laboratory test examination of TSH (Thyroid Stimulating Hormone) hormone. The aim is to determine the description of TSH levels checked periodically in patients with thyroid disorders using immunological methods. Research method is a case series method or case-by-case using secondary data from TSH hormone examination results in 2020-2022. The results were from 93 respondents based on age showed that 20-30 years old 11.8%, 31-40 years old 26.9%, 41-50 years old 26.9% and 51-60 years old 34.4%. Based on gender, 20.4% were male and 79.6% were female. Then we looked at changes in TSH hormone in patients with thyroid disorders by randomization 10 respondents. It was found that the changes were caused by consumption of anti-thyroid drugs, Thiamazole, Propranolol, Thyrozol, Propylthiouracil, Levothyroxine. Respondents with thyroid disorders were mostly found in 51-60 years and were female. There are changes in TSH hormone levels in patients with thyroid disorders were anti-thyroid drugs. The immunological method used ECLIA (Electrochemiluminescence Immunoassay) method. Factors that influence examination are the condition of sample and patient.
Gambaran Karakteristik Pasien Human Immunodeficiency Virus (HIV) dengan Hasil Pemeriksaan HCV di Puskesmas X Kota Yogyakarta Danda Fatkhurrochman; Nazula Rahma Shafriani; Farida Noor Irfani
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 7, No 3 (2026)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v7i3.16516

Abstract

The Human Immunodeficiency Virus (HIV) and the Hepatitis C Virus (HCV) share similar transmission routes, making coinfection with both a significant clinical problem, particularly in healthcare facilities such as community health centers, which play a crucial role in early detection. According to national epidemiological data from 2023, an estimated 6–10% of HIV patients are also infected with HCV, and this coinfection accelerates the progression of liver disease due to a decline in CD4+ lymphocyte function. This study aims to describe the characteristics of HIV patients based on HCV test results at Community Health Center X in Yogyakarta from April 2025 to April 2026. The study employed a descriptive quantitative design with a cross-sectional approach. The population included all HIV patients who underwent HCV testing at the facility; total sampling was used to select 84 respondents, and the data were then analyzed univariately using SPSS. The study results show that the majority of respondents were male (90.5%), aged 17–45 years, and belonged to the men who have sex with men (MSM) population group. All HIV infections occurred through sexual transmission, with no history of injection drug use or blood transfusions. Most patients (82.1%) had been on antiretroviral therapy for 1–5 years.
Co-Authors Arif Bimantara Danda Fatkhurrochman Dhiah Novalina Khafifa Usnul Mar’iyah Dg Tompo Moh.Firgiawan Dwiyanto Muthi’ah Fadhilah Aliffani Nazula Rahma Shafriani Rifka Aulia Astuti Salzabilla Poha Wahyuni Fanlai Wirna Sari