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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Manuju : Malahayati Nursing Journal Jurnal Ilmiah Kesehatan Masyarakat Joong-Ki
Dhiah Novalina
Universitas ‘Aisyiyah Yogyakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Gambaran Pemeriksaan Imunologi terhadap Pasien Tirotoksikosis di Rumah Sakit PKU Muhammadiyah Yogyakarta Periode 2020 – 2025 Muthi’ah Fadhilah Aliffani; Farida Noor Irfani; Dhiah Novalina
Malahayati Nursing Journal Vol 7, No 12 (2025): Volume 7 Nomor 12 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i12.23494

Abstract

ABSTRACT Thyroid disorders are one of the most common endocrine health problems after diabetes and affect the body's metabolism and hormonal function. This study aims to describe the immunological examination results of Thyroid Stimulating Hormone (TSH) and Free Thyroxine (FT4) levels in patients with thyrotoxicosis- type thyroid disorders atPKU Muhammadiyah Hospital, Yogyakarta, from 2020– 2025. The study employed a descriptive method with a cross-sectional approach based on secondary data from medical records and laboratories. The study sample consisted of 34 thyrotoxicosis patients selected using consecutive sampling. Data analysis was performed using univariate and bivariate methods using Spearman's correlation test. The results showed that the majority of patients were female(82.4%), with the majority aged 30–59 years (70.6%). Most patients had low TSH levels (58.8%), and all patients hadhigh FT4 levels (100%). The correlation test showed no significant association between age or gender and TSH and FT4 levels (p0.05). This study concluded that the majority of thyrotoxicosis patients were women of reproductive age,with low TSH and high FT4 levels, without any significant association with age or gender. Keywords: Thyroid disorders, Thyrotoxicosis, TSH, FT4, Imunology  ABSTRAK Gangguan tiroid merupakan salah satu masalah kesehatan endokrin terbanyak setelah diabetes dan memengaruhi metabolisme serta fungsi hormonal tubuh. Penelitian ini bertujuan untuk mengetahui gambaran hasil pemeriksaan imunologi kadar Thyroid Stimulating Hormone (TSH) dan Free Thyroxine (FT4) pada pasien gangguan tiroid jenis tirotoksikosis di RS PKU Muhammadiyah Yogyakarta periode 2020–2025. Penelitian menggunakan metode deskriptif dengan pendekatan cross-sectional berdasarkan data sekunder dari rekam medis dan laboratorium. Sampel penelitian sebanyak 34 pasien tirotoksikosis yang dipilih dengan metode consecutive sampling. Analisis data dilakukan secara univariat dan bivariat menggunakan uji korelasi Spearman’s. Hasil penelitian menunjukkan bahwa sebagian besarpasien berjenis kelamin perempuan (82,4%) dengan usia terbanyak 30–59 tahun (70,6%). Sebagian besar pasien memilikikadar. TSH rendah (58,8%) dan seluruh pasien memiliki kadar FT4 tinggi (100%). Uji korelasi menunjukkan tidak terdapat hubungan signifikan antara usia maupun jenis kelamin dengan kadar TSH dan FT4 (p0,05). Penelitian ini menyimpulkan bahwa mayoritas pasien tirotoksikosis adalah perempuan usia produktif dengan gambaran TSH rendah dan FT4 tinggi tanpa adanya hubungan bermakna dengan faktor usia dan jenis kelamin. Kata Kunci: Gangguan Tiroid, Tirotoksikosis, TSH, FT4, Imunologi
Gambaran Mikroskopis Bakteri Neisseria gonorrhoeae Pada Pasien Gonore dan Pemantapan Mutu Internalnya di Puskesmas Gedongtengen Yogyakarta: - Endita Widya Sari; Dhiah Novalina; Novita Eka Putri
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.7103

Abstract

Gonorrhea is a sexually transmitted infection with clinical symptoms of mucosal inflammation and pus formation in the genital area due to infection with the bacteria Neisseria gonorrhoeae. Transmission of gonorrhea infection can occur when the bacteria are transmitted through bodily fluids, sexual contact with sufferers, and deviant social behavior (MSM or FSW). Examination of patients diagnosed with gonorrhea requires accurate validation of results to improve internal quality, so that internal quality assurance of examinations is necessary. This study aims to determine the microscopic appearance of Neisseria gonorrhoeae bacteria in gonorrhea patients and to strengthen its internal quality assurance at the Puskesmas (Primary Health Center) Gedongtengen, Yogyakarta. The study used a descriptive study using a cross-sectional method. Data samples were taken from the medical records of patients who underwent gonorrhea examinations from January to May 2025 with a total of 35 patients, and positive results were dominated by female patients, with 8 patients. Gonorrhea examinations were carried out using the Gram staining method and then examined microscopically. The positive specimens showed clear morphology of DGNI (Gram-Negative Intracellular Diplococci) and PMN (Polymorphonuclear Cells), coffee bean-shaped, non-spore-forming, and non-motile bacteria. The entire examination process, including result validation and quality assessment, followed standard operating procedures (SOPs). The internal quality assurance assessment for gonorrhea examinations at Puskesmas Gedongtengen laboratory have met the standards with good qualifications, as stated in Puskesmas Gedongtengen SOP policy 43/UKPP/LAB/2023 concerning Internal Quality Assurance for Gonorrhea Examination.
Pelatihan Kontrol Kualitas Alat Poct (Point Of Care Testing) Glukosa Darah Bagi Warga Desa Argomulyo Di TK-PAUD Bintang-Bintang Titin Aryani; Dhiah Novalina
Joong-Ki : Jurnal Pengabdian Masyarakat Vol. 5 No. 4: Agustus 2026
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/joong-ki.v5i4.19573

Abstract

Penggunaan Point of Care Testing (POCT) glukosa darah semakin luas karena memberikan hasil pemeriksaan secara cepat dan mudah. Namun, keakuratan hasil sangat dipengaruhi oleh penerapan kontrol kualitas (quality control/QC) dan kompetensi pengguna. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan warga Desa Argomulyo di TK-PAUD Bintang-Bintang dalam melakukan kontrol kualitas alat POCT glukosa darah. Metode yang digunakan meliputi penyuluhan, demonstrasi, praktik langsung, serta evaluasi melalui pre-test dan post-test. Sebanyak 40 peserta mengikuti seluruh rangkaian kegiatan. Hasil evaluasi menunjukkan adanya peningkatan pengetahuan peserta dengan rata-rata nilai dari 61,20 menjadi 88,40 setelah pelatihan. Selain itu, sebagian besar peserta mampu melakukan prosedur kontrol kualitas sesuai standar operasional. Pelatihan ini efektif meningkatkan pemahaman dan keterampilan masyarakat dalam penggunaan alat POCT glukosa darah sehingga diharapkan dapat mendukung pemeriksaan kesehatan yang lebih akurat, aman, dan bermutu.
Analisis Hasil Uji Sensitivitas Bakteri pada Ulkus Penderita Diabetes Melitus Tipe 2 di Salah Satu Rumah Sakit Yogyakarta Fadhilah Zalfa Cahyaningrum; Dhiah Novalina; Monika Putri Solikah
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6153

Abstract

Diabetic ulcers are a condition that occurs in individuals suffering from diabetes mellitus due to damage to the nerves and peripheral arteries, leading to wound infections and damage to the skin tissue. The focus of this research is to determine the prevalence by gender, the types of bacteria that infect diabetic ulcers, and the patterns of antibiotic sensitivity at a hospital in Yogyakarta in 2024. This research employs a descriptive analytic design using a cross-sectional approach. The sampling technique uses total sampling, selecting all members of the population who meet inclusion and exclusion criteria. The data for this study were obtained from medical records during the period from January 1st to December 31st, 2024, with a total sample size of 86 diabetic ulcer patients. Of these patients, 53 are male and 33 are female who suffer from Type 2 Diabetes Mellitus with complications of diabetic ulcers. In addition, this research found 26 types of bacteria, where gram-negative bacteria are more dominant with 51 samples, while gram-positive bacteria amount to 35 samples. The most dominant type of gram-negative bacteria detected is Escherichia coli, while the most commonly identified gram-positive bacteria is Staphylococcus aureus. The antibiotics that are sensitive to gram-negative bacteria are meropenem, cefepime, and chloramphenicol. Meanwhile, the effective antibiotics against gram-positive bacteria are linezolid, gentamicin, and ciprofloxacin.
Co-Authors Endita Widya Sari Fadhilah Zalfa Cahyaningrum Farida Noor Irfani Monika Putri Solikah Muthi’ah Fadhilah Aliffani Novita Eka Putri Titin Aryani