<![CDATA[HIGHLIGHTS The survival rate of cervical cancer patients at Dr. Mohammad Hoesin Hospital was significantly higher for those undergoing surgery combined with chemotherapy or chemoradiation, with a median survival of 87.5% at 36 months, compared to other treatments such as chemotherapy or radiation alone. The loss to follow-up rate among cervical cancer patients at Dr. Mohammad Hoesin Hospital decreased over three years but remained high at 62%, with patients over 51 years old and those living far from healthcare facilities being more likely to miss follow-up appointments. ABSTRACT Objective: To describe survival patterns and associated clinical factors among cervical cancer patients treated at a tertiary referral hospital in South Sumatra over a three-year period. Materials and Methods: This retrospective cohort study analyzed cervical cancer patients diagnosed and treated at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia, between January 2021 and December 2023. A total of 494 patients (59 in 2021, 156 in 2022, and 279 in 2023) meeting the inclusion criteria were selected through total sampling. Survival analysis was conducted using the Kaplan-Meier method, and outcomes were stratified by stage, histopathological type, and treatment modality. Results: The median age of patients was 51 years, with most classified as multiparous and presenting at stage III (68.2%). Squamous cell carcinoma was the most common histopathological type (75.3%). The overall 3-year survival rate was 70.8%, with stage-specific survival rates of 82.8% (stage I), 78.2% (stage II), 70.3% (stage III), and 48.8% (stage IV). Survival was higher in patients with squamous cell carcinoma (74.5%) compared to those with adenocarcinoma (57.3%). Combination therapies, particularly surgery with chemoradiation (87%), resulted in better outcomes than monotherapies such as radiotherapy alone (28.1%). However, the study also reported a high loss to follow-up rate (62%), which may impact long-term survival evaluation. Conclusion: Survival patterns among cervical cancer patients in South Sumatra are strongly influenced by cancer stage, histological subtype, and treatment approach. Multimodal treatments were associated with improved survival, emphasizing the need for early diagnosis and comprehensive care. Addressing the high rate of loss to follow-up is essential for improving long-term outcomes in this population.]]>
