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All Journal Biomedical Journal of Indonesia PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Kesehatan Tambusai Jurnal Pengabdian Masyarakat: Humanity and Medicine Jurnal Jeumpa Indonesian Community Empowerment Journal
Inggarsih, Rara
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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Pengembangan Pelet Berbasis Nabati sebagai Pakan Alternatif untuk Intervensi Diet Vegetarian pada Tikus Putih (Rattus norvegicus) Laeto, Arwan Bin; Diba, Masayu Farah; Inggarsih, Rara; Purnamasari, Septi
Jurnal Jeumpa Vol 10 No 1 (2023): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v10i1.7411

Abstract

Penelitian eksperimen yang menggunakan intervensi diet pada tikus putih (Rattus norvegicus) terus mengalami peningkatan. Bentuk penelitian intervensi diet yang saat ini sering dilakukan adalah diet vegetarian. Penggunaan pelet standar dalam penelitian yang menerapkan diet telah banyak dilakukan, namun pengembangan pelet berbasis nabati masih belum dilakukan di Indonesia. Tujuan penelitian ini adalah untuk menganalisis efektivitas pelet nabati yang dikembangkan melalui pengukuran bobot tubuh tikus putih. Metode yang diterapkan dalam penelitian ini adalah deskriptif dengan desain eksperimen laboratorium. Jumlah pelet nabati yang dikembangkan adalah tiga, yaitu pelet untuk diet vegetarian tipe quasi, lacto-ovo dan vegan. Hasil penelitian menunjukkan bahwa pada kandungan proksimat pelet yang dianalisis, persentase karbohidrat tertinggi ditemukan pada pelet diet vegetarian tipe quasi. Kandungan persentase protein dan lemak tertinggi masing-masing ditemukan pada pelet diet vegan dan quasi. Sedangkan pelet diet lacto-ovo menunjukkan persentase kandungan air yang paling tinggi. Hasil intervensi ketiga bentuk pelet yang diberikan pada tikus putih menunjukkan penambahan bobot tubuh setiap minggu penelitian. Hasil juga menunjukkan bahwa pelet untuk tipe diet lacto-ovo memberi pengaruh yang paling tinggi terhadap peningkatan bobot tubuh tikus putih dibandingkan pelet diet lainnya. Pelet berbasis nabati efektif digunakan sebagai pakan alternatif dalam penelitian intervensi diet vegetarian pada tikus putih.
Upaya peningkatan kesadaran preventif terhadap penyakit insomnia pada generasi milenial selama masa pandemi Covid-19 Purnamasari, Septi; Laeto, Arwan Bin; Inggarsih, Rara; Diba, Masayu Farah
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I1.45

Abstract

Insomnia is a complaint in terms of difficulty initiating or maintaining or restorative sleep that lasts at least one month and causes impairment in individual functioning. Adolescent poor sleep patterns can also be caused by the use of electronic media (television, laptop, gadgets, computers, etc.) for a long duration, migraine, and smoking. The impact of sleep deprivation on adolescents can lead to decreased school academic performance, increased absenteeism, depression and traffic accidents. This community service activity is in the form of counseling and education about the cause of insomnia, the adverse effects that can occur, and efforts to prevent insomnia, promotive actions that can be taken, and assistance for independent sleep analysis and early detection so that insomnia disorders do not develop into worse types and cause other diseases through material presentation and discussion session. About 30 students of SMP IT Bina Ilmi Palembang have received benefits and solutions in the form of educational information about the cause, impact and preventive measures that can be taken to reduce the risk of insomnia which increases during the Covid-19 epidemic.
Pengayaan pembelajaran dalam upaya peningkatan pengetahuan mengenai ambigus genitalia pada mahasiswi Sekolah Tinggi Ilmu Kesehatan Abdurrahman Palembang Maritska, Ziske; Alkaf, Syifa; Inggarsih, Rara; Hafy, Zen; Purnamasari, Septi; Nindela, Rini
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 1 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I1.163

Abstract

Learning Enrichment to increase knowledge about ambiguous genitalia in students at STIKES Abdurrahman Palembang. Disorders of Sex Development (DSD) is a rare disease in which atypical gonads, chromosomes, and sex anatomy are found. Although it has a significant impact on both the physical and mental health of individuals with DSD, DSD cases are often undetected and underdiagnosed. Efforts to enrich material and learning to training on DSD for prospective midwife health workers are one of the real actions that can be taken to increase knowledge and awareness of DSD which is then expected to increase early identification efforts to improve the quality of life and patient outcomes. This community service activity was carried out for one semester through a series of activities in the form of guest lectures for enrichment of learning which were carried out in stages three times online for 55 students of STIKES Abdurrahman Palembang. Measurement of the level of knowledge of STIKES Abdurrahman students was carried out twice, namely before the series of activities began (pre-test) and after the activities were completed (post-test). From the results of the pre- and post-test, an increase in knowledge was obtained, which was originally only 36.4% with a sufficient level of knowledge at the time of the pre-test, to 69.1% with a sufficient level of knowledge at the time of the post-test. It is hoped that with the enrichment of learning, prospective midwives can know and understand DSD so that in the future they can improve early screening for ambiguous genitalia cases which can lead to improving the quality of life of sufferers.
Help-seeking Behavior of Disorders of Sex Development Patients in Palembang, Indonesia Khairunnisa, Tyas Citra; Maritska, Ziske; Purnamasari, Septi; Zulissetiana, Eka Febri; Inggarsih, Rara
Biomedical Journal of Indonesia Vol. 11 No. 2 (2025): Vol 11, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i2.220

Abstract

Introduction. Disorders of Sex Development (DSD) is a congenital disorder in which there is atypical chromosomal, gonadal, or anatomical sex development. Children with DSD are often brought to the hospital too late for care due to limited knowledge about this condition among medical practitioners. Early diagnosis is important to improve prognosis and minimize complications and comorbidities of DSD patients. Methods. This study is a descriptive observational study with a cross-sectional approach through interviews and data collection from medical records of Dr. Mohammad Hoesin Palembang Hospital in 2020 - 2023. Results. In this study, it was found that the infancy age group (28 days - 1 year) was the most common age of arrival of patients to the hospital (29%) and the most common main complaint was clitoral enlargement (19.4%). Conclusion. This study found a wide variation in patients’ chief complaints, which makes the age of arrival of DSD patients to the hospital still quite late.
Increasing Production of Freedia Herbal SME Hippocrates Medika Palembang with the Application of Extraction Machine Technology Hidayat, Rachmat; Hayati, Lusia; Parisa, Nita; Inggarsih, Rara
Indonesian Community Empowerment Journal Vol. 2 No. 1 (2022): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v2i1.17

Abstract

Indonesia is the second largest biodiversity-rich country in the world. Abundant biodiversity makes Indonesia rich in the potential of plants to be used as a variety of flavorful vegetables, dried fruit, medicine, and medicinal plants packaged in the form of herbs. Freedia is the flagship product of this SME, which is downstream from the innovative products of Rachmat Hidayat and the team. Freedia is an herb that is processed as a brewed drink to overcome diabetes mellitus disorder. The implementation of this activity uses methods of observation, interview, design, manufacturing, trial, application, and monitoring. Based on the results of the application of extraction machines in SME Hippocrates Medika, it can be concluded that the existence of these machines greatly supports the production process of freedia herbs three times more than before.
Improving the Quality of Freedia Herbal Products SME Hippocrates Medika Palembang with the Application of Capsulation Technology Hidayat, Rachmat; Hayati, Lusia; Parisa, Nita; Purnamasari, Septi; Inggarsih, Rara
Indonesian Community Empowerment Journal Vol. 2 No. 1 (2022): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v2i1.19

Abstract

Spices have been widely developed for herbal products because people believe that the product is safe without any side effects that are harmful to the health of the body. Herbal products are made from natural ingredients of plants or plants without a mixture of chemicals. One of the herbal product businesses in Palembang is SME Hippocrates Medika. SME Hippocrates Medika was established in 2019 as a communal partnership. Freedia is the mainstay product of this SME, which is downstream from the innovative products of Rachmat Hidayat and the team. Freedia is an herb that is processed as a brewed drink to overcome diabetes mellitus disorder. In an effort to improve the quality of Freedia products, efforts are made to carry out a capsulation process for the extract so that the discomfort of freedia extract can be minimized to the maximum. The application of capsulation technology greatly helps improve the quality of freedia herbal products. Where consumers feel very comfortable in the consumption of freedia herbs because there is no need to bother boiling herbs, and do not need to feel bitter when consuming herbs.
POTENSI ANTIBAKTERI FRAKSI AKTIF DAUN ALPUKAT (PERSEA AMERICANA MILL) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI SHIGELLA DYSENTERIAE Purnamasari, Septi; Inggarsih, Rara; Diba, Masayu Farah; Laeto, Arwan Bin; Arneldi, Devina Firya Yasmin; Khairunnisa, Athira
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 2 (2024): AGUSTUS 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i2.29982

Abstract

Diare masih menjadi masalah utama terutama pada kelompok umur balita dan anak-anak. World Health Organization (WHO) mendefinisikan diare sebagai kejadian buang air besar dengan konsistensi lebih cair dari biasanya dengan frekuensi tiga kali atau lebih dalam rentang waktu 24 jam. Shigella dysenteriae adalah bakteri anaerob fakultatif, non-motil, dan gram negatif yang menyebabkan diare parah dan penyakit disentri yang disebut shigellosis atau disentri basiler. merekomendasikan golongan fluoroquinolone seperti ciprofloxacin dan levofloxacin sebagai lini pertama untuk mengobati bakteri patogen. Namun, penggunaan fluoroquinolone terbatas dalam pengobatan infeksi tertentu karena telah dilaporkan beberapa kasus resistensi mikroba pada bakteri salmonella dan shigella. Alpukat (Persea americana Mill.) dikenal sebagai salah satu tumbuhan obat yang memiliki sifat antibakteri karena mengandung senyawa antibakteri seperti saponin, alkaloid, dan flavonoid dalam buah, biji, dan daunnya. Selain itu, daun alpukat juga mengandung polifenol, sementara buahnya mengandung tannin. Penelitian ini bertujuan untuk melihat efektivitas fraksi daun alpukat terhadap bakteri S. dysenteriae. Metode yang digunakan adalah difusi agar (Kirby-Bauer) dengan variasi konsentrasi larutan uji. Hasil penelitian diperoleh jenis fraksi yang aktif dari duan alpukat (Persea americana Mill.) dalam menghambat pertumbuhan S.dysenteriae adalah fraksi etil asetat. Golongan senyawa antibakteri yang terdapat dalam fraksi etil asetat daun alpukat adalah golongan alkaloid, flavonoid, steroid, tannin dan saponin. Konsentrasi hambat minimum (KHM) fraksi etil asetat dari daun alpukat adalah 250µg/ml dalam menghambat bakteri S.dysenteriae.
MOLECULAR DOCKING ON BIOACTIVE COMPOUNDS OF GENISTEIN QUERCETIN AND RESVERATROL TO BRCA1, ERA, AND EGFR RECEPTORS IN BREAST CANCER Sari H. S., Maharani Puspita; Inggarsih, Rara; Hidayat, Rachmat; Maritska, Ziske; Triwani
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.30240

Abstract

Kanker payudara merupakan kanker yang paling banyak dijumpai dan menjadi penyebab utama kematian akibat kanker pada wanita. Berbagai fitokimia dari bahan alam berpotensi memberikan efek terapeutik terhadap kanker payudara, beberapa diantaranya adalah genistein, quercetin, dan resveratrol. Penelitian ini bertujuan untuk mengetahui interaksi senyawa bioaktif genistein, quercetin dan resveratrol terhadap reseptor brca1, era dan egfrpada kanker payudara secara in silico dengan molecular docking. Molecular docking dilakukan melalui beberapa tahapan mulai dari preparasi struktur 3D senyawa bioaktif, preparasi protein target, validasi metode molecular docking, dan docking senyawa bioaktif pada protein target. Semakin rendah nilai energi ikatan antara senyawa uji dengan protein target maka ikatan yang terbentuk akan semakin kuat dan stabil. Hasil docking menunjukkan nilai energi pengikatan kompleks genistein 
Co-Authors Arneldi, Devina Firya Yasmin Arwan Bin Laeto Diba, Masayu Farah Eka Febri Zulissetiana Khairunnisa, Athira Khairunnisa, Tyas Citra Lusia Hayati, Lusia Nita Parisa Purnamasari, Septi RACHMAT HIDAYAT Rini Nindela, Rini Sari H. S., Maharani Puspita Syifa Alkaf Triwani Zen Hafy Ziske Maritska