Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal JSMARTech : Journal of Smart Bioprospecting and Technology
Salsabila, Naurah Rana Khansa
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Subchronic Exposure of Tofu Processing Wastewater: Effects on Liver Function and Blood Parameters in Wistar Rats Pratamawari, Dyah Nawang Palupi; Permatasari, Nur; Widodorini, Trining; Kusteja, Jilan Namira; Salsabila, Naurah Rana Khansa; Kusumaningrum, Novia Ayu
JSMARTech: Journal of Smart Bioprospecting and Technology Vol. 7 No. 1 (2026): Vol. 7 No. 1 (2026): JSMARTech Volume 7, No 1, 2026
Publisher : JSMARTech

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jsmartech.2026.007.01.17

Abstract

Tofu is a major soybean-based food in Indonesia; however, the potentially harmful effects of tofu processing wastewater (TPW) in home-based tofu industries have not been elucidated. This study aimed to analyze the potential hazard components (heavy metals) in TPW and the subchronic toxicity effects on liver and blood parameters in rats. Thirty-six adult male Wistar rats were divided into 6 groups (n=6): control group, TPW 1.6 ml/day (A), TPW 3.2 ml/day (B), and TPW 4.8 ml/day (C) for 28 days, respectively. The remaining two groups were assigned to TPW 1.6 mL/day (D) and TPW 4.8 mL/day (E) for 28 days, and were sacrificed 14 days after the last day of TPW administration. Body weight, liver relative weight, serum SGPT and SGOT levels, and blood count analysis were measured using standard methods. Statistical analysis was performed using one-way analysis of variance (ANOVA) with P<0.05, following Tukey honestly significant difference as the post-hoc test. This study found acceptable levels of cadmium (Cd) and lead (Pb) in TPW samples. The administration of oral TPW induced elevation of serum SGPT and SGPT levels as well as alteration of blood count parameters. This study concluded that TPW had minimal toxic effects in rats; however, further investigation into its long-term safety applications is warranted.
Co-Authors Kusteja, Jilan Namira Kusumaningrum, Novia Ayu Nur Permatasari Pratamawari, Dyah Nawang Palupi Widodorini, Trining