Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Vol 2, No 1 (2015)

Formulasi and Evaluasi Stabilitas Fisik Suspensi Ubi Cilembu (Ipomea batatas L.) dengan Suspending Agent CMC Na dan PGS Sebagai Antihiperkolesterol

Fitriani, Yeyen Nor (Unknown)
INHS, Cikra (Unknown)
Yuliati, Ninis (Unknown)
Aryantini, Dyah (Unknown)



Article Info

Publish Date
08 Jun 2016

Abstract

Drug which has small solubility in water is one of the problems that cause instability of pharmaceutical preparations. One drug practically insoluble in water is cilembu (Ipomoea batatas L.). So cilembu (Ipomoea batatas L.) made in form of suspension in order to produce stable preparations in liquid form. Making of the suspension cannot be separated from the suspending agent. CMC Na (Carboxymethylcellulose Sodium) and PGS (pulvis gummosus) is suspending agent which have been studied to produce a stable suspension. Accordingly, this study was conducted to know the suspension evaluation stability cilembu (Ipomoea batatas L.) with a suspending agent CMC Na and PGS as antihypercholesterol. Method of manufacture is dispersion method. Evaluation of physical stability test was conducted on the organoleptic, homogeneity, pH, density, viscosity, sedimentation volume, and redispersion. Data were analyzed with repeated measures and shelflife. Evaluation of physical stability the suspension cilembu with a suspending agent CMC Na and PGS on observations organoleptic, homogeneity, density and redispersion showed no difference, while the pH, viscosity and sedimentation volume were not significant differences (p< 0.05) during 30 days of storage.

Copyrights © 2015






Journal Info

Abbrev

JFST

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) is published twice a year, containing research articles, review, and short communication in pharmacy science field, including medicinal chemistry, analytical chemistry, biologjcal pharmacy, pharmaceutical sciences and ...