Adiponectin: Potential Protein Hormone as a Candidate Biomarker for Male Fertility

H Hafizuddin (Laboratory of Reproduction, Faculty of Veterinary Medicine Universitas Syiah Kuala)
Ni Wayan Kurniani Karja (Division of Reproduction and Obstetrics, Department of Veterinary Clinic, Reproduction and Pathology, Faculty of Veterinary Medicine IPB University)
Lisa Praharani (Indonesian Research Institute for Animal Production)
Mohamad Agus Setiadi (Division of Reproduction and Obstetrics, Department of Veterinary Clinic, Reproduction and Pathology, Faculty of Veterinary Medicine IPB University)

WARTAZOA Indonesian Bulletin of Animal and Veterinary Sciences
Vol 29, No 4 (2019): December 2019

Reproduction is an important factor that requires attention to increase livestock production. The application of artificial insemination (AI) technology has been developed rapidly in the world, so that availability of fertile superior male is a determinant factor of successful AI. Several recent studies have been aimed to discover male fertility biomarker, by intense research on fertility-associated proteins contained in seminal plasma. This paper describes the role of adiponectin as a biomarker candidate of male fertility. Adiponectin has a positive effect on spermatozoa functionality and steroidogenesis. This has been proven by several studies that found its expression in Sertoli cells and Leydig cells in the reproductive tract. Based on the specific role on spermatozoa functionality and steroidogenesis in supporting male fertility parameter, it is strongly suggested that adiponectin is an excellent candidate biomarker for male fertility.