Majalah Obat Tradisional
Vol 26, No 2 (2021)

Antioxidants and Antityrosinase Activity of Ethanolic Basil Leaves Extract (Ocimum americanum L.) and Eygenol

Dio Damara Handoyo (Master in Biomedical Sciences, Faculty of Medicine, Universitas Prima Indonesia)
Ermi Girsang (Universitas Prima Indonesia)
Ali Napiah Nasution (Universitas Prima Indonesia)
I Nyoman Ehrich Lister (Universitas Prima Indonesia)



Article Info

Publish Date
31 Aug 2021

Abstract

Harm effect from UV light, both UV-A and UV-B is contributing as a disease trigger and has an impact on human health. To investigate the bioactive compound, antioxidant, and the potential of basil leaves as antiaging sources particularly as the tyrosinase inhibitor. This study used phytochemical screening for the bioactive compound, DPPH scavenging activity for antioxidant assay, and tyrosinase inhibition activity for the antiaging property. The phytochemical screening shows that the basil leaves extract has flavonoid, saponin, phenol, steroid, and alkaloid. The basil leaves extract has lower antioxidant activity (20.55 ± 0.04 μg/mL) compared with eugenol (2.44 ± 0.26 μg/mL) through DPPH scavenging activity. The basil leaves extract (35.59 ± 0.83 μg/mL) has lower antiaging activity particularly as antityrosinase activity compared with eugenol (10.87 ± 0.41 μg/mL). Our findings suggest that basil leaves can be used as an antioxidant and antiaging source, particularly as a tyrosinase inhibitor.

Copyrights © 2021






Journal Info

Abbrev

TradMedJ

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, ...