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All Journal Pharmaciana: Jurnal Kefarmasian Journal of Biomedicine and Translational Research Majalah Obat Tradisional Jurnal Maternitas Kebidanan Jurnal Keperawatan Priority PRIMER (Prima Medical Journal)
I Nyoman Ehrich Lister
Universitas Prima Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PENGARUH PROMOSI KESEHATAN DENGAN MEDIA POSTER TERHADAP PENGETAHUAN IBU TENTANG KANKER PAYUDARA I Nyoman Ehrich Lister
Jurnal Maternitas Kebidanan Vol. 5 No. 2 (2020): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v5i2.1309

Abstract

According to the World Health Organization (WHO) in 2013 in Depkes RI (2015), the incidence of cancer in the year 2008 to 2012 has increased from 12.7 million cases increased to 14.2 million cases. The purpose of this study is to determine the Influence of Health Promotion By method of posters against the knowledge of mothers about breast cancer. The method in this research is queasy experimental with pre-test and post-test group design. This study was conducted in Environment II the Village of Tanjung Gusta Medan which was held in June 2019. The population of the study was 322 people, the sampling technique using random sampling with the solving formula. Methods collection data in this research use the primary data i.e. the pre-test and post-test. Data analysis was used in univariate and bivariate with the Chi-Square test. The results of this study indicate the pre-test some mothers are knowledgeable both as much as 4 people (17.4%), and post-test as many as 15 people (65.2%), knowledgeable enough at the time of the pre-test as many as 18 people (78.3%), and post-test as many as 6 people (26.1%), and less knowledgeable at the time of the pre-test as many as 1 person (4.3%), post-test as much as 2 people(8.7%). Based on this research concluded that a good knowledgeable in knowing the definition of breast cancer, the factors that cause breast cancer, how to prevent breast cancer, and how to perform a breast cancer screening
PERBANDINGAN UJI EFEKTIVITAS EKSTRAK BENGKUANG (PACHYRIZUS AROSUS) DAN DAUN SIRIH HIJAU (PIPER BETLE L.) TERHADAP BAKTERI PROPIONIBACTERIUM ACNES I Nyoman Ehrich Lister
Jurnal Keperawatan Priority Vol. 4 No. 1 (2021)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v4i1.1434

Abstract

Propionibacterium acnes is a gram-positive bacteria and consists of the Propionibacteriaceae family. Propionibacterium acnes is a bacteria that causes acne or acne vulgaris, a disease that is quite disturbing and gets the attention that occurs in adolescents and young adults. This research aimed to compare and determine the effectiveness of the extract of yam (Pachyrizus arosus) and green betel leaf (Piper betle L.) in inhibiting the growth of Propionibacterium acnes bacteria. The research variables were concentrations of yam extract (Pachyrizus arosus) 5%, 10%, 15%, 20% and green betel leaf (Piper betle L.) 1,5%, 3%, 5%, 7,5%. The results showed that there was an inhibiting zone against the growth of Propionibacterium acnes bacteria.
The protective effect of Phyllanthus emblica Linn. extract against doxorubicin-induced hepatotoxicity in rats Eka Susilawati; I Nyoman Ehrich Lister; Edy Fachrial
Pharmaciana Vol 11, No 1 (2021): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.178 KB) | DOI: 10.12928/pharmaciana.v11i1.18888

Abstract

Recently many researches have been carried out on Malacca fruit extract and its potential protective effect on in vivo organ toxicity. However, there is still no research on the protective effect of Malacca (Phyllanthus emblica L.) fruit extract on induced hepatotoxicity of anticancer drugs, especially doxorubicin in rats. The objective of this study is to determine the potential protective effect of ethanol extract of Malacca fruit (P. emblica L.) against doxorubicin-induced hepatotoxicity in rats. A preliminary phytochemical test was done followed by administration extract into doxorubicin-induced rats. Histological studies were carried out to observe the effect of the extract on liver tissue. Phytochemical test results show that the ethanol extract of Malacca fruit contains flavonoids, phenols, tannins, triterpenoids, terpenoids, and alkaloids. The increasing value of ALT and ALP of doxorubicin-induced liver tissue proved the toxicity in liver tissue caused by doxorubicin. The ethanol extract of P. emblica L. at dosage 200 mg/kg BW and dosage 400 mg/kg BW on doxorubicin-induced rats were successfully played as an antioxidant to decrease the ALT and ALPvalues and improve liver tissue doxorubicin-induced by normal hepatocytes more dominant than lysis and less mark of bleeding and congestion of blood vessels.
Antioxidants and Antityrosinase Activity of Ethanolic Basil Leaves Extract (Ocimum americanum L.) and Eygenol Dio Damara Handoyo; Ermi Girsang; Ali Napiah Nasution; I Nyoman Ehrich Lister
Majalah Obat Tradisional Vol 26, No 2 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.56081

Abstract

Harm effect from UV light, both UV-A and UV-B is contributing as a disease trigger and has an impact on human health. To investigate the bioactive compound, antioxidant, and the potential of basil leaves as antiaging sources particularly as the tyrosinase inhibitor. This study used phytochemical screening for the bioactive compound, DPPH scavenging activity for antioxidant assay, and tyrosinase inhibition activity for the antiaging property. The phytochemical screening shows that the basil leaves extract has flavonoid, saponin, phenol, steroid, and alkaloid. The basil leaves extract has lower antioxidant activity (20.55 ± 0.04 μg/mL) compared with eugenol (2.44 ± 0.26 μg/mL) through DPPH scavenging activity. The basil leaves extract (35.59 ± 0.83 μg/mL) has lower antiaging activity particularly as antityrosinase activity compared with eugenol (10.87 ± 0.41 μg/mL). Our findings suggest that basil leaves can be used as an antioxidant and antiaging source, particularly as a tyrosinase inhibitor.
Antioxidant and Elastase Inhibitor from Black Soybean (Glycine max L.) and Its Compound (Daidzein) Cendy Juliana; I Nyoman Ehrich Lister; Ermi Girsang; Ali Napiah Nasution; Wahyu Widowati
Journal of Biomedicine and Translational Research Vol 6, No 1 (2020): April 2020
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v6i1.5540

Abstract

Background: Skin aging occurs along with age. Genetic, nutrients, hormones, and sun exposure can affect directly and indirectly the structure of the skin. These things will induce an increase in free radicals which disrupts one of the most important enzymes in the extracellular matrix which is elastase enzyme. High enzyme synthesis will cause skin wrinkle. Free radicals can be inhibited by the presence of antioxidants. The plant contains natural phytochemical compounds which act as antioxidants and anti aging. Black soybeans are rich in daidzein compound, which protect against free radicals and prevent premature aging.Objective: This research evaluates the antioxidant and antiaging potential of Black Soybean (Glycine max L.) extract and its compound, daidzein.Methods: Analysis of antioxidants from black soybean extract and daidzein were carried out using ABTS scavenging activity assay. The antiaging assay was carried out through inhibition of elastase enzyme.Results: Black soybean extract had lower IC50 value of ABTS scavenging activity around 77.39±4.05 μg/ml better than daidzein with IC50 of 83.34±3.89 μg/ml. The results of elastase inhibition activity assay showed that daidzein compound has a lower IC50 value, 57.35±5.64 μg/ml compared to black soybean extract with IC50 value, 93.36±6.39 μg/ml.Conclusion: Black soybean extract had higher antioxidant. Daidzein had better elastase inhibition activity compared to black soybean extract.
GAMBARAN DIAGNOSTIK DAN PENATALAKSANAAN PASIEN OSTEOARTRITIS DI RUMAH SAKIT ROYAL PRIMA MEDAN TAHUN 2015 Kristian Yanuar Lase; I Nyoman Ehrich Lister
PRIMER (Prima Medical Journal) Vol. 4 No. 1 (2019): Edisi April
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/pmj.v4i1.3120

Abstract

Latar belakang: Osteoarthritis adalah penyakit sendi yang paling umum. Berdasarkan studi WHO tahun 2004, OA diketahui mempengaruhi 151 juta orang di seluruh dunia, mencapai 24 juta di Asia Tenggara. Jumlah ini meningkat dari tahun ke tahun. Umur, jenis kelamin, obesitas, pekerjaan dan aktivitas fisik kerap dikaitkan sebagai faktor risiko terjadinya osteoartritis.Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui gambaran diagnostik dan penatalaksanaan pasien osteoartritis di RS Royal Prima Medan tahun 2015. Metode: Penelitian ini bersifat retrospektif dan deskriptif dengan desain studi kasus. Populasi data rekam medis pasien osteoartritis tahun 2015 dengan sampel sebanyak 100 data yang diambil dengan purposive, yaitu menggunakan data lengkap. Hasil: Pada penelitian ini, kelompok umur tertinggi yang mengalami osteoartritis adalah kelompok umur 66-71 tahun sebanyak 26 orang (26%) dan paling sedikit pada kelompok umur 84-89 tahun sebanyak 1 orang (1%). Jenis kelamin terbanyak yaitu perempuan sebanyak 72 orang (72%). Lokasi sendi yang paling banyak terkena yaitu OA lutut sebanyak 71 orang (71%). Keluhan utama yaitu nyeri sendi 100%. Keluhan tambahan terbanyak adalah kaku sendi 78%. Pemeriksaan penunjang yang dilakukan adalah pemeriksaan radiologi 100%. Untuk penatalaksanaan, dokter memberikan kombinasi beberapa golongan obat. Kombinasi golongan obat yang paling banyak diberikan yaitu golongan obat OAINS + Chondrotive agent sebanyak 57 orang (57%).
Co-Authors Cendy Juliana Dio Damara Handoyo Edy Fachrial Eka Susilawati Ermi Girsang Kristian Yanuar Lase Nasution, Ali Napiah Wahyu Widowati