Jurnal Ilmiah Biosaintropis (Bioscience-Tropic)
Vol 7 No 1 (2021): Agustus 2021

Uji Toksisitas Subkronik 28 Hari Kombinasi Ekstrak Metanolik Benalu Teh dan Benalu Mangga Terhadap Profil Protein pada Tikus Wistar (Rattus norvegicus) Betina

Umu Intan Kinasih (Unisma)
Nour Athiroh Abdoes Sjakoer (Unknown)
Nurul Jadid Mubarakati (Unknown)



Article Info

Publish Date
01 Aug 2021

Abstract

There are 3 indicators for indicating a protein breakdown in the blood through a total protein, albumin, and globulin stability. A compound capable of acting as antioxidants is needed to stabilize the protein's condition. This research is aimed at identifying the toxic effects of extract’s combination from tea parasite and mango parasite on the conditions of blood’s protein by giving EMBTBM constantly for 28 days. The data analysis used ANOVA one-way by SPSS version 17.0. As for the animal test used was a female Wistar rat of 20 with four treatments are control, treatment 1 with a dose of 250mg/Kg body weight (BW). Treatment 2 with a dose of 500mg/Kg body weight (BW) and treatment 3 with a dose of 1000mg/Kg body weight (BW). The result of this research shows that there is no difference between treatment and control over the results of a total protein and albumin. But, at the result of globulin, there is a difference between treatment and control. Therefore, EMBTBM is safe for profile protein and does not cause toxicity because protein is stable and not over-reducing. Keywords:Subchronic,Total Proteins, Albumine, Globuline, Toxicity

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Journal Info

Abbrev

biosaintropis

Publisher

Subject

Agriculture, Biological Sciences & Forestry Environmental Science

Description

Jurnal ini mengkaji fenomena dan temuan penelitian di bidang biologi dan ilmu-ilmu dasar (sains) lainnya serta bidang studi di wilayah tropis. Jurnal ini ditujukan untuk menemukan solusi alternatif dalam perkembangan ilmu biologi demi kesejahteraan masyarakat Indonesia dan ...