Journal of Fundamental and Applied Pharmaceutical Science
Vol 2, No 2 (2022): February

Antioxidant Activity Evaluation from Tomatoes’ N-Hexane, Ethyl Asetate, and Water Fraction with DPPH

Ratna Sari Dewi (Unknown)
Desy Ayu Irma Permatasari (Universitas Duta Bangsa)
Tatiana Siska Wardani (Universitas Duta Bangsa)
Muladi Putra Mahardika (Universitas Duta Bangsa)



Article Info

Publish Date
07 Mar 2022

Abstract

Antioxidants are compounds that can stabilize free radicals in the body. Free radicals are highly reactive molecules as they have unpaired electrons to interact with body cell molecules. Tomatoes contain flavonoids, saponins, solanine tannins, folic acid, malic acid, citric acid, protein, fat, vitamins, minerals, and histamine, which can be used as antioxidants. This study aims to evaluate the antioxidant activity of n-hexane, ethyl acetate, water fraction, and ethanol extracts of Tomatoes and to determine the greatest antioxidant activity between n-hexane, ethyl acetate, water and vitamin C. Tomatoes (Lycopersicum esculentum Mill.) was extracted using the maceration method with ethanol  followed by fractionation using n-hexane and ethyl acetate solvents. The test of antioxidant activity to DPPH radical was conducted on n-hexane, ethyl acetate, water, and vitamin C. The antioxidant activity results, expressed by IC50 value to the n-hexane, ethyl acetate, water fraction of Tomatoes fruit, were 4.4603 ppm; 4.0868 ppm; and 4.0527 ppm, respectively. Thus, the greatest antioxidant activity was the water fraction.

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Journal Info

Abbrev

jfap

Publisher

Subject

Medicine & Pharmacology

Description

JFAPS focuses on various aspects of pharmaceutical sciences such as: Pharmaceutical Technology Pharmacology & Toxicology Pharmaceutical Chemistry Drug Discovery Traditional Medicine and Medicinal Herb Pharmaceutical Microbiology and ...