JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Vol. 9 No. 2 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA

Assessment of Antibiotic Use in ICU Patients with Pneumonia Using ATC/DDD as a Quantitative Analysis Method

Mareta Rindang Andarsari (Department Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia)
Zedny Norachuriya (Department Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia)
Sarah Mahmudatun Nabila (Department Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia)
Toetik Aryani (Department Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia)
Alfian Nur Rosyid (Department of Pulmonary, Universitas Airlangga Hospital, Surabaya, Indonesia)



Article Info

Publish Date
31 Aug 2022

Abstract

Background: Pneumonia is an infection of the lung tissue which is mainly caused by bacteria. High utilization and inappropriate use of antibiotics increase resistant bacteria, morbidity, mortality, and treatment cost. Quantitative evaluation becomes one of the indicators to assess the use of antibiotics which is one indicator of the quality of the antimicrobial resistance control program. Objective: This study aimed to evaluate the use of antibiotics an effort to increase the rationality of the use of antibiotics. Methods: This study was a retrospective observational study with a sampling method of time-limited sampling in Universitas Airlangga hospital from January until December 2019. Quantitatively using Anatomical Therapeutic Chemical (ATC)/Defined Daily Dose (DDD). Result: The samples obtained were 68 severe pneumonia patients who met the inclusion criteria. From the result of the study, there were 13 types of antibiotics used for pneumonia therapy, and the three most used were Levofloxacin, Ceftriaxone, and Meropenem, with a total of all antibiotics 73.64 DDD/100 patients-days. Most useful is parenteral Levofloxacin at 21.92 DDD/100 patient-days, Ceftriaxone at 20.45 DDD/100 patient-days and Meropenem at 14.29 DDD/100 patient-days. Conclusion: The DDD value indicates high antibiotic usage, but high antibiotic use does not imply unreasonable drug use, so we must undertake a qualitative review of antibiotic use.

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Journal Info

Abbrev

JFIKI

Publisher

Subject

Chemistry Education Health Professions Medicine & Pharmacology Other

Description

Jurnal ini adalah jurnal peer-review nasional, yang diterbitkan dua kali dalam membahas tentang topik-topik hasil penelitian di bidang pelayanan dan praktik kefarmasian, konsultasi masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait dengan erat. Jurnal ini memfokuskan pada ...